Overview
- Complete and state-of-the-art coverage of systems biology and biotechnology of E. coli
- Coverage of all levels of omics and genome-scale computational studies in E. coli
- Comprehensive coverage of engineering E. coli, and biotechnological applications
- Contributions from world-leading experts in the fields
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About this book
Systems biology is changing the way biological systems are studied by allowing us to examine the cell and organism as a whole. Systems biotechnology allows optimal design and development of upstream to downstream bioprocesses by taking a systems-approach. E. coli has been a model organism for almost all biological and biotechnological studies. This book brings together for the first time the state-of-the-art reviews by the world-leading experts on systems biology and biotechnological applications of E. coli. The topics covered include genomics and functional genomics, resources for systems biology, network analysis, genome-scale metabolic reconstruction, modelling and simulation, dynamic modelling and simulation, systems-level analysis of evolution, plasmids and expression systems, protein synthesis, production and export, engineering the central metabolism, synthetic biology, and systems metabolic engineering of E. coli. This book provides readers with guidance on how a complex biological system can be studied using E. coli as a model organism. It also presents how to perform synthetic biology and systems metabolic engineering studies on E. coli with successful examples, the approaches of which can be extended to other organisms. This book will be a complete resource for anyone interested in systems biology and biotechnology.
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Keywords
Table of contents (20 chapters)
Reviews
"This is a very interesting and powerful collection of chapters covering a wide spectrum of systems biology frontiers in E. coli and written by recognized leaders in the field..... a must have publication for years to come"
Professor Eleftherios Terry Papoutsakis, University of Delaware, U.S.A.
Editors and Affiliations
Bibliographic Information
Book Title: Systems Biology and Biotechnology of Escherichia coli
Editors: Sang Yup Lee
DOI: https://doi.org/10.1007/978-1-4020-9394-4
Publisher: Springer Dordrecht
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Science+Business Media B.V. 2009
Hardcover ISBN: 978-1-4020-9393-7Published: 17 April 2009
Softcover ISBN: 978-90-481-8118-6Published: 21 October 2010
eBook ISBN: 978-1-4020-9394-4Published: 20 March 2009
Edition Number: 1
Number of Pages: XXI, 462
Topics: Biochemistry, general, Biotechnology, Microbiology, Microbial Genetics and Genomics, Applied Microbiology