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Advances in DNA Repair in Cancer Therapy

  • Book
  • © 2013

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Overview

  • Reveals the latest developments in DNA repair in cancer therapy and the latest progress in research
  • Discusses novel DNA repair enzymes such as PARP and DNA-PK
  • Appeals to cancer researchers as well as oncologists

Part of the book series: Cancer Drug Discovery and Development (CDD&D)

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About this book

​A comprehensive review of the recent developments in DNA repair research that have potential for translational applications. The book explains in detail the various biological mechanisms by which cancer cells can circumvent anticancer therapy and limits its usefulness in patients. They also review the impact of such novel inhibitors of DNA repair mechanisms as methylguanine-DNA-methyltransferase. Also examined are inhibitors of other DNA repair enzymes such as PARP and DNA-PK. The book captures-for both cancer researchers and oncologists dealing with hallmark "relapse" or "drug resistance" phenomena on a daily basis-the many exciting new uses of DNA repair inhibitors, either alone or in combination with anticancer therapies.​

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Keywords

Table of contents (12 chapters)

Editors and Affiliations

  • Jewish General Hospital, Montreal, Canada

    Lawrence Panasci

  • , Department of Oncology, McGill University, Montreal, Canada

    Raquel Aloyz

  • McGill University, Department of Medicine and Oncology, Faculty of Medicine, Montreal, Canada

    Moulay Alaoui-Jamali

Bibliographic Information

  • Book Title: Advances in DNA Repair in Cancer Therapy

  • Editors: Lawrence Panasci, Raquel Aloyz, Moulay Alaoui-Jamali

  • Series Title: Cancer Drug Discovery and Development

  • DOI: https://doi.org/10.1007/978-1-4614-4741-2

  • Publisher: Humana New York, NY

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Science+Business Media, LLC 2013

  • Hardcover ISBN: 978-1-4614-4740-5Published: 06 December 2012

  • Softcover ISBN: 978-1-4899-9308-3Published: 28 January 2015

  • eBook ISBN: 978-1-4614-4741-2Published: 09 December 2012

  • Series ISSN: 2196-9906

  • Series E-ISSN: 2196-9914

  • Edition Number: 1

  • Number of Pages: VIII, 312

  • Topics: Cancer Research, Molecular Medicine

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