Overview
- Presents the available mixture models in a clear and simple way, allowing readers to apply tools to their own research
- Includes novel methods for prioritizing mixtures for study
- Surveys what is known about interactions between chemical and non-chemical stressors and discusses various approaches for including non-chemical stressors in cumulative risk assessments
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Keywords
Table of contents (18 chapters)
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Combined Exposures
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Prioritizing Mixtures for Study
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Toxicology
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Chemical Mixtures Risk Assessment
Editors and Affiliations
About the editors
Dr. Cynthia Rider is a toxicologist with the National Toxicology Program, National Institute of Environmental Health Sciences, where she has been actively involved in mixtures research including work with polycyclic aromatic hydrocarbons and herbal products. She received her B.S. from Tulane University and her Ph.D. from North Carolina State University in Environmental Toxicology. She completed post-doctoral training in the Reproductive Toxicology Branch of the National Health and Environmental Effects Research Laboratory, U. S. Environmental Protection Agency (EPA) and the Nicholas School of the Environment at Duke University. Dr. Rider has been an active member of the mixtures community through reviewing papers, serving on an EPA panel on cumulative risk assessment of phthalates, and developing mixtures-related scientific program proposals for Society of Toxicology annual meetings.
Jane Ellen Simmons is Chief of the Pharmacokinetics Branch, National Health and Environmental Effects Research Laboratory, US EPA. She received an MSPH in Environmental Management and Protection and a PhD in Toxicology from the Department of Environmental Sciences and Engineering, School of Public Health, University of North Carolina at Chapel Hill. Her research focus areas include: models, methods and approaches for both defined mixtures and environmentally realistic complex mixtures; integrating chemical and toxicological evaluations of chemical mixtures; and much more. She is a Diplomate of the American Board of Toxicology. She co-chaired the International Toxicology of Mixtures Conference and has served on the HiWate Science Advisory Board, on review panels for the Food and Drug Administration and North Carolina State University and Advisor to the US EPA RTP Chapter of the National Training Leadership Organization. Dr. Simmons has also authored more than 90 peer-reviewed journal articles and 15 book chapters and reports.
Bibliographic Information
Book Title: Chemical Mixtures and Combined Chemical and Nonchemical Stressors
Book Subtitle: Exposure, Toxicity, Analysis, and Risk
Editors: Cynthia V. Rider, Jane Ellen Simmons
DOI: https://doi.org/10.1007/978-3-319-56234-6
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer International Publishing AG 2018
Hardcover ISBN: 978-3-319-56232-2Published: 20 March 2018
Softcover ISBN: 978-3-030-09617-5Published: 15 December 2018
eBook ISBN: 978-3-319-56234-6Published: 16 February 2018
Edition Number: 1
Number of Pages: XIV, 556
Number of Illustrations: 23 b/w illustrations, 54 illustrations in colour
Topics: Pharmacology/Toxicology, Epidemiology, Environmental Health