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Therapeutic Intranasal Delivery for Stroke and Neurological Disorders

  • Book
  • © 2019

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Overview

  • Comprehensive overview of studies of intranasal delivery
  • Expected to have great impact on the field of translational stroke research
  • Useful for researchers, physicians, and drug developers?

Part of the book series: Springer Series in Translational Stroke Research (SSTSR)

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About this book

The blood-brain-barrier serves to encapsulate and protect the central nervous system, but it also presents a major barricade to therapeutic drug delivery. Poor penetration is the most common hurdle to translating a promising experimental therapy that uses invasive delivery methods to a clinically useful application. In the last 10 years, intranasal delivery of various therapeutic compounds including small chemicals, large proteins, and even stem cells has proven to be very effective in bypassing the blood-brain-barrier and has led to some important advances in translational research for stroke and other neurological diseases. The proposed book will bring together reports from various labs around the world who have had successes in pre-clinical studies of intranasal therapies for various diseases including adult and perinatal stroke, Alzheimer's, Parkinson's, and others.​

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Keywords

Table of contents (11 chapters)

Editors and Affiliations

  • Department of Neurology, University of Pittsburgh, Pittsburgh, USA

    Jun Chen

  • Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University School of Medicine, Baltimore, USA

    Jian Wang

  • Departments of Anesthesiology and Neurology, Emory University School of Medicine, Atlanta, USA

    Ling Wei

  • Department of Physiology, Loma Linda University School of Medicine, Loma Linda, USA

    John H. Zhang

Bibliographic Information

  • Book Title: Therapeutic Intranasal Delivery for Stroke and Neurological Disorders

  • Editors: Jun Chen, Jian Wang, Ling Wei, John H. Zhang

  • Series Title: Springer Series in Translational Stroke Research

  • DOI: https://doi.org/10.1007/978-3-030-16715-8

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Nature Switzerland AG 2019

  • Hardcover ISBN: 978-3-030-16713-4Published: 17 June 2019

  • eBook ISBN: 978-3-030-16715-8Published: 03 June 2019

  • Series ISSN: 2363-958X

  • Series E-ISSN: 2363-9598

  • Edition Number: 1

  • Number of Pages: VI, 153

  • Number of Illustrations: 3 b/w illustrations, 8 illustrations in colour

  • Topics: Neurosciences, Neurology

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