Exosomes: from basic research to clinical diagnostic and therapeutic applications in cancer Salomé Araujo-AbadJosé Marcos BernaCamino de Juan Romero Review Open access 19 September 2024
Circadian system disorder induced by aberrantly activated EFNB2-EPHB2 axis leads to facilitated liver metastasis in gastric cancer Qing LiYuxuan LinChunchao Zhu Research 19 September 2024
Low-dose SAHA enhances CD8+ T cell-mediated antitumor immunity by boosting MHC I expression in non-small cell lung cancer Wenqian DongBing HeBaolong Wang Research Open access 16 September 2024
A review on the functional characteristics of the c-Myeloproliferative Leukaemia (c-MPL) gene and its isoforms Mohammad Amjad HussainShankar Prasad DasSuparna Laha Review 16 September 2024
BHLHE41, a transcriptional repressor involved in physiological processes and tumor development Caroline BretFabienne Desmots-LoyerThierry Fest Review Open access 10 September 2024
Targeting tumor associated macrophages (TAMs) reprograms tumor immune microenvironment to promote solid tumor immunotherapy Chunliu HuangXiumei WangJun Chen Comment 05 September 2024
Correction to: EMP2 induces cytostasis and apoptosis via the TGFβ/SMAD/SP1 axis and recruitment of P2RX7 in urinary bladder urothelial carcinoma Chien-Feng LiTi-Chun ChanYow-Ling Shiue Correction 03 September 2024
TRIM28 promotes tumor growth and metastasis in breast cancer by targeting the BRD7 protein for ubiquitination and degradation Changning XueHanbing MengMing Zhou Research 02 September 2024
Telomere transcripts act as tumor suppressor and are associated with favorable prognosis in colorectal cancer with low proliferating cell nuclear antigen expression Philip KienzlAbigail J. DeloriaKlaus Holzmann Brief Report Open access 02 September 2024
PSMD2 overexpression as a biomarker for resistance and prognosis in renal cell carcinoma treated with immune checkpoint and tyrosine kinase inhibitors Xianglai XuJiahao WangJianming Guo Research 02 September 2024
Next-generation BCMA-targeted chimeric antigen receptor CARTemis-1: the impact of manufacturing procedure on CAR T-cell features Belén Sierro-MartínezVirginia Escamilla-GómezEstefanía García-Guerrero Research Open access 27 August 2024
Single-cell RNA transcriptomic analyses of tumor microenvironment of ovarian metastasis in gastric cancer Guoyu ChenMingda ZhangHaizhong Feng Research 20 August 2024
Pre-existing cell subpopulations in primary prostate cancer tumors display surface fingerprints of docetaxel-resistant cells Stanislav DrápelaBarbora KvokačkováKarel Souček Research Open access 20 August 2024
Characterization and proteomic analysis of plasma-derived small extracellular vesicles in locally advanced rectal cancer patients Haiyan ChenYimin FangKefeng Ding Research 20 August 2024
Optimizing the spatial immune landscape of CD103+CD8+ tissue-resident memory T cells in non-small cell lung cancer by neoadjuvant chemotherapy Guanqun YangMengyu HuXiaorong Sun Research 19 August 2024
Loss of histone deubiquitinase Bap1 triggers anti-tumor immunity Hong ChangMingxia LiYong Yu Research Open access 14 August 2024
ZNF468-mediated epigenetic upregulation of VEGF-C facilitates lymphangiogenesis and lymphatic metastasis in ESCC via PI3K/Akt and ERK1/2 signaling pathways Jinrong ZhuXiangyu QiuRongxin Zhang Research 14 August 2024
Interferon Gamma Inducible Protein 30: from biological functions to potential therapeutic target in cancers Sen ZhangLiwen RenJinhua Wang Review 14 August 2024
Tertiary lymphoid structures and their therapeutic implications in cancer Xun ChenPan WuWei Xiong Review 12 August 2024
Disrupting YAP1-mediated glutamine metabolism induces synthetic lethality alongside ODC1 inhibition in osteosarcoma Hongsheng WangYining TaoWei Sun Research 08 August 2024
Marine derived macrolide bryostatin 4 inhibits the TGF-β signaling pathway against acute erythroleukemia Yan-Yu KouJie LiuFan Yang Research 31 July 2024
COLEC10 inhibits the stemness of hepatocellular carcinoma by suppressing the activity of β-catenin signaling Mei-Na CaiDong-Mei ChenYi-Fan Lian Research 30 July 2024
Acidity and hypoxia of tumor microenvironment, a positive interplay in extracellular vesicle release by tumor cells Silvia PeppicelliLido CaloriniElena Andreucci Review Open access 18 July 2024
Panoramic tumor microenvironment in pancreatic ductal adenocarcinoma Xiaoying LiWanting HouDan Cao Review 15 July 2024
A dual-targeting approach with anti-IL10R CAR-T cells engineered to release anti-CD33 bispecific antibody in enhancing killing effect on acute myeloid leukemia cells Zhifeng YanRunxia GuJianxiang Wang Research 15 July 2024
Fasting in combination with the cocktail Sorafenib:Metformin blunts cellular plasticity and promotes liver cancer cell death via poly-metabolic exhaustion Juan L. López-CánovasBeatriz Naranjo-MartínezAlberto Diaz-Ruiz Research Open access 11 July 2024
Comprehensive multiomics analysis of the signatures of gastric mucosal bacteria and plasma metabolites across different stomach microhabitats in the development of gastric cancer Bingsen WangJiahui LuanMei Shi Research Open access 04 July 2024
Suppressing SENP1 inhibits esophageal squamous carcinoma cell growth via SIRT6 SUMOylation Jianmin GuShaoyuan ZhangLijie Tan Research Open access 02 July 2024
The PPP2R1A cancer hotspot mutant p.R183W increases clofarabine resistance in uterine serous carcinoma cells by a gain-of-function mechanism Michiel RemmerieRüveyda DokVeerle Janssens Research 18 June 2024
IRE1α inhibitor enhances paclitaxel sensitivity of triple-negative breast cancer cells Min WuLin ZhangZhengfang Yi Research 18 June 2024
Deciphering the molecular landscape: evolutionary progression from gynecomastia to aggressive male breast cancer Chuang YangZhonglin WangHandong Sun Research 18 June 2024
Antitumor activity of afatinib in EGFR T790M-negative human oral cancer therapeutically targets mTOR/Mcl-1 signaling axis Jung-Min HanKyu-Young OhSung-Dae Cho Research Open access 18 June 2024
ONECUT2 is a druggable driver of luminal to basal breast cancer plasticity Irene ZamoraMirian GutiérrezMirja Rotinen Research Open access 31 May 2024
HVEM in acute lymphocytic leukemia facilitates tumour immune escape by inhibiting CD8+ T cell function Yujia LiuLixiang WangWei Yi Research 29 May 2024
OrganoIDNet: a deep learning tool for identification of therapeutic effects in PDAC organoid-PBMC co-cultures from time-resolved imaging data Nathalia FerreiraAjinkya KulkarniM. Andrea Markus Research Open access 28 May 2024
A systematic review on the culture methods and applications of 3D tumoroids for cancer research and personalized medicine Jessica KallaJanette PfneisslGerda Egger Review Open access 28 May 2024
Deciphering fatty acid biosynthesis-driven molecular subtypes in pancreatic ductal adenocarcinoma with prognostic insights Junyi XuMingzhu LiuPing Lu Research 16 May 2024 Pages: 1475 - 1491
Targeted gene delivery systems for T-cell engineering Fengling WangYong HuangWei Wang Review 16 May 2024
SPG21, a potential oncogene targeted by miR-128-3p, amplifies HBx-induced carcinogenesis and chemoresistance via activation of TRPM7-mediated JNK pathway in hepatocellular carcinoma Ping ZhouWei YaoFan Zhu Research 16 May 2024
Research advances in the molecular classification of gastric cancer Dike ShiZihan YangQingqu Guo Review Open access 08 May 2024
Correction to: 3D bioprinted tumor model: a prompt and convenient platform for overcoming immunotherapy resistance by recapitulating the tumor microenvironment Zhanyi ZhangXuebo ChenShengnan Ren Correction Open access 30 April 2024 Pages: 1127 - 1127
Targeting Dectin-1 and or VISTA enhances anti-tumor immunity in melanoma but not colorectal cancer model Siavash MashhouriAmirhossein RahmatiShokrollah Elahi Research Open access 26 April 2024
Rituximab potentially improves clinical outcomes of CAR-T therapy for r/r B-ALL via sensitizing leukemia cells to CAR-T-mediated cytotoxicity and reducing CAR-T exhaustion Yangzi LiQingya CuiXiaowen Tang Research Open access 25 April 2024
LILRB2 promotes immune escape in breast cancer cells via enhanced HLA-A degradation Zhiyuan JiangQianru HuangHui Zhao Research 24 April 2024
Chordoma cells possess bone-dissolving activity at the bone invasion front Katsuhiro KawaaiYumiko OishiKoichi Matsuo Research Open access 23 April 2024
Exploring the impact of PDGFD in osteosarcoma metastasis through single-cell sequencing analysis Yujing HuangDongyan CaoAina He Research Open access 23 April 2024
Correction to: Microbial metabolite trimethylamine-N-oxide induces intestinal carcinogenesis through inhibiting farnesoid X receptor signaling Wanru ZhangXiali QinHailong Cao Correction 16 April 2024 Pages: 1201 - 1204
Integrated analysis of single-cell RNA-seq and bulk RNA-seq reveals immune suppression subtypes and establishes a novel signature for determining the prognosis in lung adenocarcinoma Shengqiang MaoYilong WangLi Zhang Research 15 April 2024
Establishment, characterization, and biobanking of 36 pancreatic cancer organoids: prediction of metastasis in resectable pancreatic cancer Soon-Chan KimHa-Young SeoJa-Lok Ku Research Open access 15 April 2024