Overview
- Offers guidance in how to optimize the pre-analytical handling of tissue and improve diagnostic quality
- Discusses the importance of cold ischemia time
- Examines the value of vacuum-based preservation and two-temperature fixation
- Includes supplementary material: sn.pub/extras
Part of the book series: Recent Results in Cancer Research (RECENTCANCER, volume 199)
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About this book
This book presents an overview of the most important current developments in the pre-analytical handling of tissue. It addresses in particular potential ways to improve the situation whereby methods employed in the pre-analytical phase – the period from surgical removal of tissue to the start of pathological processing – have remained essentially unchanged for decades with only modest standardization. It is examined how the pre-analytical period can be optimized, resulting not only in an increase in diagnostic quality but also in a reduction in processing time and costs. Among the key topics examined are the so-called cold ischemia time between tissue removal and fixation, the potential superiority of vacuum-based preservation over immediate formalin fixation, two-temperature fixation, molecular analysis methods, and the pre-analytics of specimens from particular tissues. Readers will find this book to be an important update that reveals the full importance of the pre-analytical phase for quality of pathological work-up.
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Table of contents (12 chapters)
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Front Matter
Editors and Affiliations
Bibliographic Information
Book Title: Pre-Analytics of Pathological Specimens in Oncology
Editors: Manfred Dietel, Christian Wittekind, Gianni Bussolati, Moritz Winterfeld
Series Title: Recent Results in Cancer Research
DOI: https://doi.org/10.1007/978-3-319-13957-9
Publisher: Springer Cham
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer International Publishing Switzerland 2015
Hardcover ISBN: 978-3-319-13956-2Published: 10 March 2015
Softcover ISBN: 978-3-319-34982-4Published: 06 October 2016
eBook ISBN: 978-3-319-13957-9Published: 30 January 2015
Series ISSN: 0080-0015
Series E-ISSN: 2197-6767
Edition Number: 1
Number of Pages: VI, 133
Number of Illustrations: 4 b/w illustrations, 61 illustrations in colour
Topics: Oncology, Pathology, Surgery, Laboratory Medicine