Overview
- Provides a basic-science introduction and theory related to infection and antimicrobial studies
- Covers key topics in infection and advances in integration of both antimicrobial and osteoinductive properties
- Illustrates how current technologies can be used to better understand and develop advanced biomaterials with both osteoinductive and antimicrobial properties that address delayed bone regeneration and infection simultaneously
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About this book
This book covers the latest research in biofilm, infection, and antimicrobial strategies in reducing and treating musculoskeletal, skin, transfusion, implant-related infections, etc. Topics covered include biofilms, small colony variants, antimicrobial biomaterials (antibiotics, antimicrobial peptides, hydrogels, bioinspired interfaces, immunotherapeutic approaches, and more), antimicrobial coatings, engineering and 3D printing, antimicrobial delivery vehicles, and perspectives on clinical impacts. Antibiotic resistance, which shifts the race toward bacteria, and strategies to reduce antibiotic resistance, are also briefly touched on. Combined with its companion volume, Racing for the Surface: Pathogenesis of Implant Infection and Advanced Antimicrobial Strategies, this book bridges the gaps between infection and tissue engineering, and is an ideal book for academic researchers, clinicians, industrial engineers and scientists, governmental representatives in national laboratories, and advanced undergraduate students and post-doctoral fellows who are interested in infection, microbiology, and biomaterials and devices.
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Keywords
Table of contents (25 chapters)
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Clinical Significance of Infection
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Pathogenesis of Infection
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Advanced Antimicrobial Strategies to Treat Infection
Editors and Affiliations
About the editors
Thomas Webster is the Chemical Engineering Department Char and Art Zafiropoulo Endowed Chair at Northeastern University. Prof. Webster has graduated 144 students. His lab group published 9 textbooks, 48 book chapters, 403 articles, and 32 provisional/full patents. Prof. Webster has received numerous honors: 2012, Fellow, American Institute for Medical and Biological Engineering; 2013, Fellow, Biomedical Engineering Society; 2015, Wenzhou 580 Award; 2015, Zheijang 1000 Talent Program; 2016, IMRC Chinese Academy of Science Lee-Hsun Lecture Award; 2016, Fellow, Biomaterials Science and Engineering; and 2016, Acta Biomaterialia Silver Award. He also frequently appears on the BBC, NBC, ABC, Fox, National Geographic, Discovery Channel and many other news outlets talking about science.
Malcolm Xing is a professor of University of Manitoba. His research focuses on smart biomaterials for tissue engineering, nanomedicine, wearable biosensor, implantable bio-robot and 3D/4D bioprinting. He has obtained awards such as National Science & Engineering Research Council Discovery Accelerator Supplement Award, Canada Foundation for Innovation - Innovation Fund, CBA-BA Young Investigator Award in ACS 2017 and Dr. J.A. Moorhouse Fellowship of the Diabetes Foundation of Manitoba. Dr. Xing was the invited speaker of 2019 Society for Biomaterials Annual Conference and Keynote speaker of 2019 Canada Biomaterials Society (CBS) Conference, and the conference chair of CBS2017. His research has been covered in media including Time, Fortune, Discovery, Science, ACS headline news, RSC, CTV, CBC, etc.
Dr Fintan Moriarty isPrincipal Investigator and Leader of the Musculoskeletal Infection team at the AO Research Institute Davos in Switzerland. He has extensive expertise in the application of preclinical in vivo models to address clinically relevant questions on the problem of fracture-related infection (FRI). Particular interests have been the development of prophylactic and therapeutic strategies against FRI, including those caused by antibiotic resistant pathogens. He has published over 60 peer-reviewed articles and book chapters, and has served as editor of a book on biomaterial associated infection. He is a scientific editor of the eCM Journal, co-organiser of the eCM conference on orthopedic infection, and guest lecturer at the Department Health Science and Technology (D-HEST) of the ETH Zurich.
Bibliographic Information
Book Title: Racing for the Surface
Book Subtitle: Pathogenesis of Implant Infection and Advanced Antimicrobial Strategies
Editors: Bingyun Li, Thomas Fintan Moriarty, Thomas Webster, Malcolm Xing
DOI: https://doi.org/10.1007/978-3-030-34475-7
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Nature Switzerland AG 2020
Hardcover ISBN: 978-3-030-34474-0Published: 03 March 2020
Softcover ISBN: 978-3-030-34477-1Published: 03 March 2021
eBook ISBN: 978-3-030-34475-7Published: 02 March 2020
Edition Number: 1
Number of Pages: XI, 650
Number of Illustrations: 36 b/w illustrations, 122 illustrations in colour
Topics: Biomedical Engineering/Biotechnology, Biomaterials, Biomedical Engineering and Bioengineering