Overview
- Focuses on experimental techniques for measuring and analyzing immune cell dynamics
- Emphasizes lymphocyte programmed cell deaths in different contexts
- Features expert tips and key implementation advice to guarantee successful results
- Includes supplementary material: sn.pub/extras
Part of the book series: Methods in Molecular Biology (MIMB, volume 979)
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About this book
Many questions remain unresolved as researchers continue to characterize and define the nature of normal immune homeostasis and determine how these processes are dysregulated in immunodeficiency, as well as in autoimmune and lymphoproliferative disorders. Immune Homeostasis: Methods and Protocols focuses on experimental techniques for measuring and analyzing immune cell dynamics, with a particular emphasis on examining lymphocyte programmed cell death in different contexts. With contributions by leading experts in the field, the collection examines detailed protocols for studying various pathways of apoptosis and necrosis in different types of hematopoietic cells, both in vitro and in vivo, methods for studying the maintenance of lymphocyte populations in the steady-state or following infectious challenges in both mice and humans, and technical insights into state-of-the-art genomics tools, among other topics. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Valuable and easy to use, Immune Homeostasis: Methods and Protocols serves as an important toolkit for basic and clinical scientists interested in examining various aspects of immune homeostasis in both normal and disease-related contexts in order to further study the dynamic processes that contribute to homeostasis of the immune system.
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Keywords
Table of contents (16 protocols)
Editors and Affiliations
Bibliographic Information
Book Title: Immune Homeostasis
Book Subtitle: Methods and Protocols
Editors: Andrew L. Snow, Michael J. Lenardo
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-62703-290-2
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media New York 2013
Hardcover ISBN: 978-1-62703-289-6Published: 09 February 2013
Softcover ISBN: 978-1-4939-5968-6Published: 23 August 2016
eBook ISBN: 978-1-62703-290-2Published: 11 February 2013
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XI, 215
Topics: Immunology