Abstract
Dendritic cells (DCs) are professional antigen-presenting cells that can regulate both innate and adaptive immune responses. Programmed cell death of DCs plays an important role in maintaining the homeostasis of DCs and in the regulation of immune responses. Methods to measure the rate of spontaneous and T cell-mediated cell death of DCs are described here. These procedures can be adapted to study the induction of dendritic cell death in different settings of immune responses.
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Acknowledgements
This work was supported by NIH grants R01AI074949, R01AI056210 (J.W.), and R01DK083164 (M.C.).
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© 2013 Springer Science+Business Media New York
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Chen, M., Huang, L., Wang, J. (2013). Analyses of Programmed Cell Death in Dendritic Cells. In: Snow, A., Lenardo, M. (eds) Immune Homeostasis. Methods in Molecular Biology, vol 979. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-290-2_6
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DOI: https://doi.org/10.1007/978-1-62703-290-2_6
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Publisher Name: Humana Press, Totowa, NJ
Print ISBN: 978-1-62703-289-6
Online ISBN: 978-1-62703-290-2
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