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Muscarinic Receptor: From Structure to Animal Models

  • Book
  • © 2016

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Overview

  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts

Part of the book series: Neuromethods (NM, volume 107)

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About this book

This volume provides methods for characterization of muscarinic receptor in crystallography studies that advanced our understanding of structural properties and activation mechanism of muscarinic receptors and are cornerstone in molecular modeling and computer‑based approaches to study muscarinic receptors. Muscarinic Receptor: From Structure to Animal Models guides readers through binding techniques, protocols to investigate molecular properties of muscarinic receptors, protocols to study muscarinic receptors in the central nervous system using autoradiography and PET studies and protocols on animals with knock-out and knock-in muscarinic genes to study role of muscarinic receptors in physiology and behavior. Written in the popular Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your own laboratory.

Concise and easy-to-use, Muscarinic Receptor: From Structure to Animal Models aims to ensure successful results in the further study of this vital field.

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Keywords

Table of contents (14 protocols)

Editors and Affiliations

  • Institute of Physiology, Charles University, Prague, Czech Republic

    Jaromir Myslivecek

  • Department of Neurochemistry, Acad. of Sciences of the Czech Rep. Institute of Physiology, Prague, Czech Republic

    Jan Jakubik

Bibliographic Information

  • Book Title: Muscarinic Receptor: From Structure to Animal Models

  • Editors: Jaromir Myslivecek, Jan Jakubik

  • Series Title: Neuromethods

  • DOI: https://doi.org/10.1007/978-1-4939-2858-3

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media New York 2016

  • Hardcover ISBN: 978-1-4939-2857-6Published: 05 August 2015

  • Softcover ISBN: 978-1-4939-4971-7Published: 01 November 2016

  • eBook ISBN: 978-1-4939-2858-3Published: 31 July 2015

  • Series ISSN: 0893-2336

  • Series E-ISSN: 1940-6045

  • Edition Number: 1

  • Number of Pages: XII, 287

  • Number of Illustrations: 35 b/w illustrations, 42 illustrations in colour

  • Topics: Neurosciences

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