1 Introduction

Considerable attention has been paid to the role of universities in regional economic development and innovation. Regional knowledge networks and modes of engagement between universities and the business community have increasingly been encouraged by public policies. The most recent development in the field has also formally identified a new mission in addition to the two traditional roles of teaching and research. Researchers use the terms “third mission” (Laredo 2007) or “knowledge transfer” (Bekkers and Freitas 2008) to identify a new set of activities through which higher education institutions interact with their communities. The university-based knowledge spillovers over the local economy that have been paid considerable attention in the literature relate to the creation of new firms (Acosta et al. 2011; Bonaccorsi et al. 2014a) and to the university-firm collaboration, through the commercialisation of academic knowledge, involving patenting and licensing of inventions as well as academic entrepreneurship (Laursen et al. 2011; De Fuentes and Dutrénit 2016). Therefore, universities have become key elements in building regional innovation systems (Caniëls and van den Bosch 2010). For example, the establishment of new companies, based on technologies derived from university research, is a well recognized driver of regional economic development (Hayter et al. 2017). Incubators developed by higher education institutions are effective in supporting new entrepreneurial initiatives (Auricchio et al. 2014). Innovative start‐ups are also an effective way to facilitate technology transfer from universities to the economy (Boh et al. 2015). See Maietta (2015), for a description of the channels through which university-firm research and development (R&D) collaboration impacts firms’ product and process innovations. Among the several contributions that universities can make in order to speed up local economic development, education and knowledge creation through academic research play an important role (Leten et al. 2014). Although this knowledge can be easily transferred at low cost (i.e., downloaded from the Internet) and therefore is not tied to a firm’s location, proximity to high‐output universities may be important for accessing research networks (Audretsch and Lehmann 2005). Indeed, a conclusion has been reached especially by the literature dealing with technologically advanced sectors: the number of scientific publications in high-ranked journals is a relevant indicator of academic research quality to assist firms in their choice of R&D partners.

However, some authors have questioned whether the kind of new knowledge and technology produced by regional universities is helpful to local firms (Bonaccorsi 2017), particularly in the case of firms with low absorptive capacity in mature and low-tech sectors. Regional-level studies on the impact of academic knowledge spillovers do not always highlight positive effects of universities on regional innovation in Europe (Ghinamo 2012). This weak evidence could be explained by the absence in Europe of a specialised public research infrastructure. Indeed, there is a scarce match between the regional knowledge base and the needs of industry—i.e. problems with the orientation of public sector research to industry needs (Prokop and Stejskal 2018). Even though academic research quality is important when firms choose universities as R&D collaboration partners, a still open question in the literature is therefore whether only top-tier universities are relevant for regional development. From industry perspectives, academic research excellence may even present some comparative disadvantages, and second and third-tier universities may also be important for industry innovation (Mansfield and Lee 1996). Indeed, lower-tier universities can probably better solve the problem of firms not interested in cutting-edge research. In this case, firms might not look for star universities (Hong and Su 2013). In this direction, Barra et al. (2019) recently analysed whether academic excellence, recognized at international level-measured by indicators of top publications and citations-can enhance innovation of firms, showing that top-10 publications of second-tier universities exhibit the highest positive association with product innovation of science-based sectors, but negative associations with top-10 publications of first- and second-tier universities are evidenced for process innovation in this macro-sector.

Moreover, the indirect effect (e.g. due to formal university-firm interaction) of university-firm collaboration on firm innovativeness is well-documented (Lööf and Heshmati 2002; Belderbos et al. 2004; Baba et al. 2009; Eom and Lee 2010; Protogerou et al. 2017). However, part of the literature has also underlined the importance of informal activities, rather than patenting and academic entrepreneurship, which are even considered significantly more valuable by many companies and also involve more academics (Perkmann et al. 2013). Informal relationships between universities and firms are indeed alternative and important channels of technology transfer (Bönte and Keilback 2005). This direct impact of academic research on firm-level innovation has not been extensively investigated and the few existing papers suggest a trade-off between publications vs. informal collaborations with the industry (Maietta 2015; Maietta et al. 2017; Barra et al. 2019).

Furthermore, changes occurred over the last decades in the European higher education institutions are not of secondary importance. Indeed, as a result of the convergence process started by the Bologna Declaration (see the “Appendix” for a brief summary of the structural changes in higher education system in Europe), the European higher education system has been substantially reformed and the role that universities play in enhancing regional innovation systems has been potentially reinforced.Footnote 1 However, the amount of academic duties has been growing due to the new administrative work, linked to teaching and research quality requirements, to the increasing number of students (Viola 2014) and to the general advent of mass university education (Perotti 2007). The relationship between teaching and research has also loosened because of the reduction of tenured and tenure tracked positions. As a consequence, the Humboldtian tradition of a strong connection between research and teaching, which is widespread in continental Europe, might be weakened as an instrument of knowledge spillovers from academic research to firms.Footnote 2 European universities have also faced changing funding regimes with the introduction of national systems of funding conditional on evaluation of research output or national assessment exercises (see again the “Appendix” for a brief summary of the differences, in terms of the funding regimes, among the European countries for which the empirical analysis of the paper is done). The introduction of a performance-based research funding system increased university competition for prestige and enhanced research productivity, but run also into costs. Because of the reliance on the academic elite in their design and implementation, they may suppress scientific novelty, innovation and intellectual diversity. Teaching quality has decreased, because of a trade-off between teaching quality and grades given by the national assessment exercise (Barra and Zotti 2016). More importantly given the context examined in this paper, the interaction with industry and application of research activities, with economic benefits such as firm innovation, could be discouraged (Moscati et al. 2010; Maietta 2015). These unintended consequences might lead to an internationally approved ivory tower of scholarship, and damage societies over the long term (Hicks 2012, 2013).Footnote 3

The primary objective of the paper is to analyse how the “knowledge context” in which the firm operates-in terms of research and education activities at local universities-affect the university-firm relationship. More specifically, we investigate the impact of the volume of scientific publications at local universities on firm’s propensity to develop new product and processes. Furthermore, the second aim of the paper is to measure to what extent academic research has to be excellent in order to enhance local industrial innovation. We argue that although academic research is an important determinant of university-firm collaboration, however a still debated question in the literature is whether only top-tier universities are relevant for knowledge transfer from university to industry. Thirdly, the paper aims at disentangling and quantifying the direct channels through which academic research drives product and process innovation, once we control for the formal university-firm collaboration (mainly via contract and collaborative research). To conclude, the paper’s final objective is to explore whether education act as a channel of local university-based knowledge spillovers. The local university is represented by the higher education institutions located in the same province (NUTS3 level) where the firm is located. The volume of research is represented by the number of publications while education activities are proxied by the number of national and international students of the universities within the province where the university is located. Local first (second and third) tier universities are defined as the universities, located in the same province where the firm is located, with the highest (second and third highest) number of publications to explore whether the firm’s propensity to develop innovation depends only on star universities or whether also lower-tier institutions may play a role at local level. Importantly, this paper deviates from Barra et al. (2019) in two main specifications. Instead of focusing the whole discussion about research excellence, this paper put the emphasis on publication counts as a primarily measure of quantity. Moreover, while in Barra et al. (2019) a definition of what constitutes a “first tier university” based on an international comparison of reputation is used, this paper, instead, considers the largest (in term of publications) university in a province as “first tier”. The drawback of such definition of academic research volume is that a university that would be first tier in a rural province may be “lower tier” in an urban region, where there are several other universities. However, what makes important and worthwhile examining the impact of the volume of academic research at local universities on the capacity of local firms to develop new products and processes is the following idea. It is true that tying with partners of high academic production is generally preferred to close geographical location (Laursen et al. 2011). However, distant universities are generally not chosen as firm R&D partners in the earliest phase of the projects (Broström 2010).

The source of data on company innovation is the European Firms in a Global Economy (EFIGE) dataset from an extensive survey carried out in seven European countries in 2010. Information on universities is collected at the NUTS 3 level since this geographic unit enables to capture the spillover effects of public research (Bonaccorsi 2014). It is gathered from a range of sources: European University Data Collection (EUMIDA), European Tertiary Education Register (ETER), Scopus by Elsevier, and the Academic Ranking of World Universities (ARWU). We use a simultaneous multi-equation approach that addresses both the endogeneity of R&D decisions and the simultaneity of internal and external R&D investment. Since the dependent variables are ordinal, the simultaneous approach is a multivariate probit model. Our dependent variables reflect the choice of: investing in internal R&D; investing in external R&D in university/research labs and other firms/consultants; and innovating products and processes. The determinants of firm innovation are those that have been used successfully in preceding studies (e.g. Maietta 2015) alongside several specifications of variables reflecting the university scientific composition and output.

The remain of the article is organized as follows. Section 2 reviews the related literature and develops the study hypotheses. Section 3 describes the methodology and the sources of the data. Section 4 presents the results of our analysis. Robustness check is provided in Sect. 5, while Sect. 6 concludes with a discussion and implications.

2 Literature review and hypotheses

Knowledge spillovers from universities to firms is channelled through research published in scholarly journals. Scientific research results in knowledge that could lead to firms’ innovation activities (Bercovitz and Feldman 2007; Autant-Bernard 2001) and it could also be disseminated within the regional environment leading to an improvement of local economies (Goldstein and Renault 2004). Academic research has a positive impact on the regional distribution of innovation (Del Barrio-Castro and García-Quevedo 2005) through new product development, industry formation, job creation and access to advanced professional and management services (Walshok 1997). Indeed, a positive relationship between the scientific productivity of European universities and their entrepreneurial effectiveness such as contract research, patent activities, and spin-off creation has been found (Van Looy et al. 2011). Among the main channels through which university research impacts industrial R&D, there are published papers and reports, public conferences and meeting as well as informal information exchange and consulting (Cohen et al. 2002). Positive and significant effects of university scientific research are found indicating that firms benefit from scientific research of local universities.Footnote 4 The presence of a critical mass of academic research (such as the number of university publications in peer reviewed journals) creates opportunities for firms to link up to strong local scientific networks of university researchers, collaborate with university research groups and university spin-offs (Leten et al. 2014). Looking at publications as a source of ideas seems to be a particularly important element for the innovative process. Indeed, the probability of a firm to develop R&D project is positively affected by its willingness to acquire knowledge. This is the screening of publications such as reading scientific articles in order to identify competences in universities and select the right researchers (Fontana et al. 2006). However, if local collaboration may stimulate more innovation when involving a high-output partner (Nishimura and Okamura 2010), these externalities are not always widespread either because limited in the geographic space or in the scientific place (Autant-Bernard 2001). Indeed, knowledge codified in publications is more localized than knowledge codified in academic patents since its effect on knowledge-intensive firms is confined within the boundaries of the province where the universities are located (Bonaccorsi et al. 2014b). The first study hypothesis is the following:

H1

The volume of research affect the firm’s propensity to innovate at local level.

The relationship between the reputation of faculty and the contribution to industry is not as strong as expected in all industries, the impact of academic quality and geographical proximity not being homogeneous across disciplinary fields. Indeed, firms seem more likely to look for a high-quality faculty or department, paying less attention to where the university is located, when basic research is considered. On the other hand, when applied R&D research is considered, firms seem to prefer working with a lower ranked university located closer to firm R&D laboratories. This behaviour may be explained by the fact that more face-to-face interaction between academics and firm employees is needed for applied research, while this interaction is less binding for basic research. Moreover, the differences between top- and second-tier universities may be more evident for basic research than for applied R&D, and beyond a certain threshold of academic quality, firms may no longer consider the additional cost attached to this collaboration worthwhile, as some top tier universities may impose more stringent conditions than those imposed by less prestigious universities. Indeed, some firms could decide to invest in supporting research at leading universities also to obtain access to promising students and graduates.

In general, by building relationships with highly ranked universities, firms gain more credibility in the market for their products’ quality; therefore, improved reputation and legitimacy would mostly drive the decision to collaborate with prestigious universities. Firms make their decision to support R&D applied research according to the reputation of the university as well as to the presence of star scientists (Karlsson and Andersson 2006) based on the motivation that prestigious universities will make available the best technology to firms more cheaply and quickly (Mansfield 1991). Adams (2005) underlined that firms more interested in funding cutting-edge research will collaborate with top-tier universities regardless of the distance between them. Laursen et al. (2011) find that co-location with top tier universities promotes collaboration and that firms decide to collaborate with a university partner giving preference to its academic quality over the geographical location. Their findings show that firms first choose to collaborate with local top-tier universities and, second, with a non-local, but highly ranked, university rather than cooperating with a local second-tier institution. Szücs (2018) analyses the impact of university– firm collaboration on the number of granted patents, patent citations and indicators of patent novelty, considering the Webometrics university ranking. A positive impact, also increasing with the universities’ academic quality, has been found.

However, although it is true that top-tier departments were more often cited by firms, universities with adequate to good and marginal faculties, according to the US National Academy of Science rating, also obtained good citations (Mansfield and Lee 1996). The evidence of a localized effect of academic research is offered by Calcagnini et al. (2016). They analyse the distance of innovative new firms’ location from the closest university, measuring academic research according to the marks given by the national performance-based research funding system. A positive effect is evidenced only for the social science area, where knowledge is less codified and needs a direct interaction to be transmitted. Analogously, Maietta (2015) finds that firms which are closer to an academic institution develop more product innovation. However, bibliometric and research assessment indicators of the closest university exert a negative direct impact on firm product innovation. Barletta et al. (2017) also find evidence a negative association between the research groups’ scientific productivity, defined as the number of Scopus publications per researcher, and the research groups’ technology transfer activities. Maietta et al. (2017) find that the number of national Scopus publications presents a positive marginal effect on university-firm collaboration and product innovation but does not impact process innovation. Furthermore, the impact of national academic rankings on university spin-offs is not statistically significant (Fini et al. 2017). Based on these arguments, the following hypothesis may be formulated:

H2

Research production at local second and third tier universities has the same of even greater knowledge spillover than that at local top-tier universities.

Academic research production is recognised as an important determinant of university-firm interaction, mainly via contract and collaborative research (Laursen et al. 2011) and licensing (Mowery and Ziedonis 2015). Along this line, a few papers have underlined the effect of knowledge transfer from universities on firm product and process innovation and of university-firm collaboration on firm innovativeness (Lööf and Heshmati 2002; Belderbos et al. 2004; Baba et al. 2009; Eom and Lee 2010; Protogerou et al. 2017) and most of them focus on whether academic research indirectly affect firm’s innovative outputs through formal university-firm interaction. The direct impact of academic research on firm-level innovation, instead, has not been extensively investigatedFootnote 5 (Maietta 2015; Maietta et al. 2017; Barra et al. 2019). Nevertheless, informal types of cooperation for innovation, such as those which are not based on contractual agreements, like informal communication between employees from cooperating firms (Bönte and Keilbach 2005), may play an important role in the exchange of technical knowledge. For instance, a research team of one firm may ask researchers working in a R&D department of another firm for technical information and may provide in turn technical information to those researchers, although legally binding contracts do not exist and firms are not engaged in joint R&D (again, see Bönte and Keilbach 2005). We follow this definition regarding informality as it also coincides with previous definitions established in other studies related to university-firms collaboration that label as informal the lack of formalised agreements, as well as define informal activities those providing ad hoc advice and networking with practitioners (Bonaccorsi and Piccaluga 1994; Olmos-Peñuela et al. 2014).Footnote 6 Academic engagement that also involves informal relationships has a long tradition, particularly at universities with a technical orientation of education and third-mission activities. More importantly, informal participation in collaborative activities may be pursued as an alternative resource mobilisation by highly motivated and successful individuals who are, however, not necessarily affiliated to higher quality research institutions, where fewer resources are available (Perkmann et al. 2013). These considerations led to the formulation of the following hypothesis:

H3

Informal relationship between universities and firms is an alternative and important channel of technology transfer.

Finally, spillovers to local business via university links are present due to the local generation of a skilled workforce (Faggian and McCann 2006). Graduates are a critical mechanism through which the knowledge produced in the higher education system gets transferred into the labour market (Marinelli 2013), and employers seem increasingly to be demanding workers with a graduate qualification (Wößmann 2008). Graduates may also decide to start up new firms that boost the dynamics of the local economic environment (Florax 1992; Goldstein et al. 1995). Indeed, more skilled and educated workers have a higher chance of being involved in the implementation of new technologies (Wozniak 1987), and so the skill composition of the labour force affects the technology used by firms. High quality human capital, as measured by the number of university graduates, explains local entrepreneurship in high-tech industries (Acosta et al. 2011) and has a positive effect on the creation of knowledge-intensive firms (Bonaccorsi et al. 2014b).

It is also true, however, that the education role played by universities may conflict with research and third mission in the absence of adequate resources (to be devoted to this specific aim) and of indicators of this type of output, which need to be taken into account to evaluate the advancement of scholars’ careers. Achieving high-quality teaching by monitoring scholars’ teaching performance could be perceived as a potential future source of private funding to augment university budgets but could also decrease the probability of university-firm collaboration. Indeed, the possibility of a trade-off between university missions, particularly between academic excellence, as measured by the number of publications in high-ranked journals, versus local knowledge spillovers useful for economic growth, has been suggested in the literature (Moscati et al. 2010; Perotti 2010) and may also dumper the quality of the teaching. As academic jobs typically involve multiple tasks, incentives based on the performance in a specific task, such as research output, could reduce workers’ effort in another, such as teaching. These considerations led to the formulation of the following hypothesis:

H4

The role of education as a channel of university-based local knowledge spillovers may have been weakened due to a possible trade-off between university missions.

3 The empirical framework

3.1 The econometric approach

Our econometric model consists of five simultaneous equations related to dependent binary variables which are jointly described by a multivariate probit model. The model is based on a five-equation structure in which the estimation results of the second and third equations are used as regressors in the fourth and fifth equations, as follows:

$${{\text{y}}_{{{\text{1i}}}}^{*} = {\mathbf{x}}_{{{\text{1i}}}}^{^{\prime}} {{\varvec{\upbeta}}}_{{1}} { + }\varepsilon_{{{\text{1i}}}} }$$
(1)
$${{\text{y}}_{{{\text{2i}}}}^{*} = {\mathbf{x}}_{{{\text{2i}}}}^{^{\prime}} {{\varvec{\upbeta}}}_{{2}} { + }\varepsilon_{{{\text{2i}}}} } $$
(2)
$${{\text{y}}_{{{\text{3i}}}}^{*} = {\mathbf{x}}_{{{\text{3i}}}}^{^{\prime}} {{\varvec{\upbeta}}}_{{3}} { + }\varepsilon_{{{\text{3i}}}} }$$
(3)
$${{\text{y}}_{{{\text{4i}}}}^{*} = \gamma_{24} {\text{ y}}_{{{\text{2i}}}}^{*} + \gamma_{34} {\text{ y}}_{{{\text{3i}}}}^{*} + {\mathbf{x}}_{{{\text{4i}}}}^{^{\prime}} {{\varvec{\upbeta}}}_{{4}} { + }\varepsilon_{{{\text{4i}}}} }$$
(4)
$${{\text{y}}_{{{\text{5i}}}}^{*} = \gamma_{25} {\text{ y}}_{{{\text{2i}}}}^{*} + \gamma_{35} {\text{y}}_{{{\text{3i}}}}^{*} + {\mathbf{x}}_{{{\text{5i}}}}^{^{\prime}} {{\varvec{\upbeta}}}_{{5}} { + }\varepsilon_{{{\text{5i}}}} }$$
(5)

These are the five latent variables. \(y_{1}^{*}\) is intra muros R&D investment; \(y_{2}^{*}\) is R&D collaborations with universities and/or research labs; \(y_{3}^{*}\) is R&D collaborations with other firms and/or consultants; \(y_{4}^{*}\) is product innovations and \(y_{5}^{*}\) is process innovations. xki is vectors of exogenous variables, which influence those probabilities for firm i. \({{\varvec{\upbeta}}}_{{\text{k}}}\) is parameter vectors. γkl is scalar parameters which describe a structural relation between yk and yl and therefore allow for causal interpretations. Finally \(\upvarepsilon _{{{\text{ki}}}}\) are error terms, which are assumed to be jointly normal with the unknown correlation coefficient, ρkl. The latter measures how far the unobserved factors influence yk and yl, if ρlk = 0 cannot be rejected. This implies that the equations need not to be estimated as a system and can be estimated separately.

The latent variables \(y_{{{\text{ki}}}}^{*}\) are not observed. However, the binary variables, yki, are observed, and these are linked to the former according to the following rule:

$$\left\{ {\begin{array}{*{20}l} {y_{ki } = 1,\quad {\text{if}}\quad y_{ki}^{*} > 0_{;} } \hfill \\ { y_{ki }} = 0\quad {\text{otherwise;}}\quad k = 1, \ldots ,5 \hfill \\ \end{array} } \right.$$
(6)

Basically, our model includes three reasons why we might observe yk (where k = 2, 3) and y4 (or y5) to be correlated. First, a causal relation due to the influence from yk on y4 (or y5) through the parameter γk4 (or γk5). Second, yk and y4 (or y5) may depend on correlated observed variables (the xk’s. Third, yk and y4 (or y5) may depend on correlated unobserved variables (the εk’s) (Arendt and Holm 2006). The common latent factor structure of the multivariate probit framework makes possible both to correct the potential sample selection and to control for the potential endogeneity of the R&D investment decision. Indeed, the coefficient ρlk can be interpreted as the degree of endogeneity of yk to ul where k = 2, 3 and l = 3, 4 (Monfardini and Radice 2008). The resulting multivariate probit model can be described as an instrumental variable framework for categorical variables and can be estimated using the simulated maximum likelihood method.

This method uses the Geweke-Hajivassiliour-Keane smooth recursive conditioning simulator to evaluate the multivariate normal distribution. The simulated probabilities are unbiased and bound within the (0, 1) interval (Cappellari and Jenkins 2003). All the equations in (1) can be estimated separately as single probit models but the estimated coefficients are inefficient because the correlation between the error terms is neglected and the simultaneity is not taken into account (Maddala 1983).

The estimation of a multivariate probit model with endogenous binary regressors requires some consideration for the identification of the model parameters. Maddala (1983) proposes that the exogenous covariates in the reduced form equations should contain at least one regressor not included in the structural equations. However, Wilde (2000) shows that no exclusion restrictions on the exogenous variables are required for parameter identification, when there is sufficient variation in the data. This last condition is ensured by the assumption that each equation contains at least one varying exogenous regressor, an assumption which is rather weak in economic applications. Given the assumption of joint normality, the multivariate probit model is identified by functional form. Wilde’s contribution makes it clear that theoretical identification does not require availability of any additional instruments for the endogenous variables. However, the presence of equation-specific regressors in formally identified models may improve convergence and make the estimation results more robust to distributional misspecifications (Monfardini and Radice 2008).

3.2 The data and the descriptive statistics of the variables

The source of company information is the EFIGE database. The dataset consists of a representative sample for the manufacturing industry of surveyed firms with more than 10 employees in Austria, France, Germany, Hungary, Italy, Spain and the United Kingdom. The sampling design has been structured following a three dimension stratification: industry (NACE Rev. 2 codes), region (NUTS 1 level) and size class (10–19; 20–49; 50–99; 100–249 and more than 250 employees). The database contains quantitative and qualitative information on R&D and innovation. More specifically, firms are asked whether product and/or process innovation had been introduced during the years 2007–2009. The questionnaire also collects information regarding whether the R&D was intra muros or acquired from external sources such as universities/research labs and other firms/consultants. Other information used here includes the amount of R&D expenditure and whether the firm benefits from tax allowances and financial incentives for R&D investment or other activities. Size classes have been used with respect to the number of employees, along with other firm characteristics, such as the presence of skilled employees (that is graduates), age and gender of the current Chief Executive Officer (CEO) or company head. The age of the firm and its current legal form, firm NUTS3 location and whether the firm, in the three years, applied for a patent, registered an industrial design or a trademark and claimed a copyright have been also included.

The second source of data is represented by the EUMIDA and ETER databases. These projects aimed to build a complete census of European universities (Bonaccorsi 2014) and included a pilot data collection with particular emphasis on research-active universities. For each university, the data contain the number of national and international students, the presence of Ph.D. degrees, as well as information regarding the fields of education and the year in which the university was funded. Further information on the field of education is also sourced from the EU Agri Mapping project (Chartier 2007). All the information at the university level has been averaged out or summed up at the NUTS3 level and then matched with firm-level characteristics.

Thirdly, the main indicator of academic research used in this study is sourced from Scopus, one of the largest database of peer-reviewed literature. We specifically hand collected, for each university, the overall number of publications in scientific journals, book and conference proceeding in the field of science, technology, medicine, social sciences, and art and humanities in the year 2007.Footnote 7 Scopus has been chosen among other sources of information. Indeed, it provides good tools to track, analyse and visualize research output of an institution using both the institution name and its English translation. Furthermore, Scopus publications may well represent the internationalization degree of the national academic research output. The number of publications associated with each university has been then summed up at the NUTS3 level and matched with company-level characteristics. This allow us to assign to each firm in the dataset the indicator of academic research corresponding to the sum of publications of all the universities by the NUTS3 where the firm is located.

Fourthly, we use the ARWU database, also known as the Shanghai academic ranking of the universities, which ranks universities according to research output criteria. Among them, there is the number of papers published in Nature and Science and papers indexed in Science Citation Index-Expanded and Social Science Citation Index. It has been used in this paper to obtain an indicator of academic research output normalized by the output level of the university reaching the highest research output in the world in 2008, the intermediate year of the period under study.

Finally, information on total patents, which are used as proxy of technology level, by NUTS3 and by selected technology fields, is sourced from the Organisation for Economic Co-operation and Development (OECD) Patent Database.

Table 1, identifies and defines the variables used in our analysis, the characteristics of the sample and provides their descriptive statistics.

Table 1 Variables and descriptive statistics

3.3 The empirical specification

The empirical specification of the five equations is as follows:

Intra muros R&D = f1 (R&D subsidies, Skilled employees, CEO age, CEO gender, Firm age, firm size dummies, firm legal form dummies, intellectual property dummies, Rurality of the province, country dummies or university characteristics and output).

R&D collaboration with partnerm = fk (Intra muros R&D intensity, extra muros R&D intensity with partner ≠ m, R&D acquired abroad, R&D subsidies, Skilled employees, CEO age, CEO gender, Firm age, firm size dummies, firm legal form dummies, intellectual property dummies, Rurality of the province, country dummies or university characteristics), where m = universities/research labs or other firms/consultants and k = 2, 3.

Innovation j = fj (R&D collaboration with universities/research labs, R&D collaboration with private firms/consultants, R&D intensity, Subsidies, Skilled employees, CEO age, CEO gender, Firm age, firm size dummies, firm legal form dummies, intellectual property dummies, Rurality of the province, industrial sector dummies, country dummies or university characteristics), where j = product or process.

As Table 1 shows, almost 5% of our firms have R&D collaborations with a university or research lab. Among all firms in the sample, 49% have introduced product innovation, and 44% have introduced process innovation. R&D intensity, measured as the percentage of the total turnover that the firm has invested in R&D on average in the three years is around 3.6%. Over the same time span, 48% of the firms undertook intra muros R&D activities.

Several specifications of variables reflecting university characteristics and output have been tested alternately. The baseline specification is Model 1, which includes only national dummies. Model 2 tests the role of average university composition (proxied by the average age of the universities, the presence of medical schools, the type of faculties in the university, and the presence of Ph.D. programmes). Model 3 and Model 4 analyse the university outputs in terms, respectively, of the number of national and international students, the academic research indicator and the number of total patents also split in different sectors (biotechnology, informatics and commercial technology, nanotechnology, medical and pharmaceutical). Model 5 tests the effect of scientific composition and academic output through the age of the universities, the presence of medical schools, the type of faculties, the presence of Ph.D. programmes, the number of national and international students, the academic research indicator and the number of total patents. Model 6, as explained in Sect. 4.2, analyses the academic research indicator of the first-tier university vs that of all the other universities in the province. Finally, Model 7 analyses the academic research indicator of the first- and second-tier universities vs that of all the remaining universities in the province.

Industrial sectors vary in terms of sources, paces and rates of technological change which modulate firm requirement to be engaged in innovation networks and the extent and character of such networking. As a consequence, we grouped firms in the four Pavitt classes (Pavitt 1984) to analyse the academic research indicator of the first-tier university vs that of all the other universities in the province also by Pavitt macro-sector.

Multicollinearity among the regressors is assessed by computing the variance inflation factor (VIF). The empirical specification is based on a sample of 14,744 observations.

4 The empirical evidence

4.1 The drivers of innovation and of firm R&D collaboration

The marginal effects of the multivariate probit regressions are reported for various specifications in Tables 37 (Models 1 to 7). The standard errors of the coefficients have been clustered around the country in which the firm is located. The likelihood ratio test, which was conducted on the hypothesis that the \(\rho\) s are jointly null, is highly significant and supports the multivariate five-equation framework. The correlation coefficients (see Table 2) are significant for the internal R&D investment in that the presence of intra muros R&D is correlated with product and process innovation. The two equations related to external collaborations are also correlated and the two equations related to product and process innovation.

Table 2 Significance and value of the correlation coefficients among the errors of the Eqs. (1)–(5)

Table 3 reports the marginal effects for Eq. (1), for intra muros R&D investment. The dummy for R&D subsidies is positive and highly statistically significant. The dummies for very small and small firm size and sole proprietorship are negatively correlated with in-house R&D. As expected, skilled employees are positively correlated with in-house R&D.

Table 3 Multiprobit regression. Marginal effects for the dependent variable (existence of) intra muros R&D investment

Among the university characteristics, the age of the universities is not conducive to intra muros R&D investment. The type of faculties becomes significant after that the education variables and the academic research indicator are added. Both the academic research indicator and the number of total patents are conducive to intra muros R&D investment.

Table 4 reports the marginal effects for Eq. (2) (R&D collaboration with universities/research labs). The intra-muros R&D intensity has a negative and significant effect on the probability of building a collaboration with universities/research labs. This suggests substitution between intra-muros R&D investment and extra-muros R&D investment with universities. The extra-muros R&D intensity with other firms/consultants has a positive but weakly significant effect. The R&D subsidy dummy is positive and highly significant. Foreign universities/research labs may be chosen as company R&D partners because the dummy for R&D acquired abroad is positive and significant. The dummy for very small firm size is highly significant and negative. Applying for a patent and registering a trademark are positive and highly significant determinants. They, indeed, guarantee appropriability of jointly developed innovation taking into account that competitors may even collaborate with the same local research institution.

Table 4 Multiprobit regression. Marginal effects for the dependent variable R&D collaboration with universities/research labs

With regards to the university characteristics, age is positive and statistically significant suggesting that older universities are more involved in R&D collaboration with firms because of longstanding established networks between firms and universities. The number of total patents is negative and statistically significant probably because of rivalry between university-firm co-patents and the patents produced by other firms in the province. The number of international students seems to be detrimental to university-firm collaboration (even though not robust). It could be due to the fact that universities with international students are relatively more involved in codified knowledge teaching and research, and less focused on applied industrial research. The academic research indicator is not significant underlining no effect of the average academic research output on university-firm collaboration. It might happen that local firms, using cutting-edge technology, prefer to collaborate with more distant universities. While local and more productive universities prefer to collaborate with distant large firms on richly supported cutting-edge research projects. Alternatively, for more applied research, it could be that firms prefer to collaborate with close universities even if they produce less Scopus publications.

Table 5 reports the marginal effects for Eq. (3) (R&D collaboration with other firms/consultants). The intra-muros R&D intensity has a negative effect on the probability of building a collaboration with other firms/consultants. This suggests substitution (and not complementarity) between intra-muros R&D and extra-muros R&D investments with other firms. Whereas the extra-muros R&D intensity with universities or research labs has a positive effect. The dummy for R&D subsidies is still positive and highly statistically significant and in addition the dummy for R&D acquired abroad is positive and significant with a high marginal effect. The dummy for sole proprietorship is negative and significant. The presence of medical schools and of agriculture faculties is not conducive to R&D collaboration with other firms or consultants.

Table 5 Multiprobit regression. Marginal effects for the dependent variable R&D collaboration with other firms/consultants

Table 6 reports the marginal effects for Eq. (4) (product innovation). R&D intensity is positive and statistically significant. R&D collaborations with universities/research labs and with other firms/consultants are also positive and highly significant. The age of a firm has a positive and statistically significant effect on product innovation. CEO age appears to be significantly detrimental to product innovation, whereas being a male CEO is conducive to product innovation. The dummy for very small firm size is highly significant and negative. Cooperatives are less likely to innovate their products.

Table 6 Multiprobit regression. Marginal effects for the dependent variable product innovation

The university age is negative and statistically significant suggesting higher knowledge spilllovers of younger universities. The presence of a medical school favours product innovation. The number of national students is detrimental to product innovation, probably due to the fact that as more national students are enrolled, academics have to deal with additional teaching hours, leaving little time for third mission activities. More specifically, most local national students are enrolled in 3-year general degrees, but generally the connection between academic research and teaching at first-level degrees is weak. On the other hand, the connection between academic research and teaching at 2-year specialization degrees is higher but the mobility of these graduates is not locally confined. Finally, the pressure to publish on international journals to reach a good research assessment may have decreased the quality of teaching up to the point of weakening the role of education as a channel of local knowledge spillovers.

The academic research indicator is always positive and statistically significant meaning an important direct effect on product innovation. This variable may catch the effect of academic knowledge spillovers through informal relationships and doctors employed by firms.

Finally, Table 7 reports the marginal effects for Eq. (5) (process innovation). Process innovation is strongly determined by R&D collaboration both with universities/research labs and with other firms/consultants. R&D intensity and skilled employees are positive and highly significant. Process innovation is also favoured by public incentives. Very small and small firms are less likely to innovate their processes as well as proprietorship. Regarding the university characteristics, the presence of the faculty of humanities is detrimental to process innovation whereas the presence of the faculty of business and law is beneficial. The academic research indicator is not statistically significant.

Table 7 Multiprobit regression. Marginal effects for the dependent variable process innovation

4.2 Academic research and local knowledge spillovers

So far, the empirical evidence suggests that academic research has an important direct effect on the firm’s propensity to develop product innovation. In order to explore whether this result is mainly driven by the local first-tier university or whether also lower-tier universities play a role, we disaggregate the total number of publications. First of all, we differentiate local universities according to their research output. The local first-tier university is defined as the university with the highest number of Scopus publications. The local second-tier university is defined as the university with the second highest number of Scopus publications. Finally, local third-tier universities are all the other universities co-located in the firm NUTS3. The first-tier university is assigned the sum of its Scopus publications, and second-tier university is assigned the sum of its Scopus publications. Third-tier universities are assigned the sum of all Scopus publications of the other universities co-located in the firm NUTS3. We also grouped the publications of all the other universities apart from the first-tier one naming them Lower-tier universities (1) and the publications of all the other universities apart from the first- and second-tier (Lower-tier universities (2)).

This give us the possibility to explore whether the firm’s propensity to develop innovation depends only on the activities of first-tier universities or whether also lower-tier institutions in the province where the firm is located play an important role. It is important to underline that we construct a measure of academic research that is based on a local rather than an international comparison. This is to capture the possibility that local universities, where a more face-to-face interaction between academics and firms is possible, can probably better solve the problem of firms not interested in cutting-edge research.

The main results are generally confirmed, therefore we report only the models with countries dummies and all the university characteristics (Tables 3 to 7, Model 6). When a first-tier university is present in the same province where the firm is located, then the firm is more likely to invest in intra-muros R&D (Table 3, Model 6) and to develop product innovation (Table 6, Model 6). Interestingly, the publications of the first-tier university are negative and statistically significant, having a detrimental effect on the development of process innovation (Table 7, Model 6). The explanation may be that first-tier universities prefer to interact with firms on product innovation activities which may generate valuable economic benefits, like patents, whereas this is not the case for process innovation (Duguet and Lelarge 2012). Lower-tier universities also positively contribute to increase the investment in intra-muros R&D (Table 3, Model 6).

Results in presence of first-, second- and third-tier universities (again for the main specifications) are summarised in Tables 37, Model 7. The empirical evidence shows that the academic production of both first-tier and lower-tier universities increases the likelihood that the firm invest in intra-muros R&D (Table 3, Model 7). The publications of the first two-tier universities have a positive marginal effect on firm’s propensity to develop product innovation (Table 6, Model 7). This evidence underlines that benefits from high output departments are especially associated with downstream related activities—i.e. successful market introduction of new products (Bishop et al. 2011). The publications of third- and further-tier universities increases firm’s propensity to develop process innovation (Table 7, Model 7). The publications of the first-tier university are again negative and statistically significant, having a detrimental effect on the development of process innovation (Table 7, Model 7).

5 Robustness check

In order to make our results more reliable and to further examine whether academic research may enhance firms innovation, several robustness checks are performed.

Firstly, we broaden the approach followed in the paper by considering the relationship between local economy and academic entrepreneurship. More specifically, one important aspect that has been taken into account in the literature on technology transfer is the role played by local conditions such as the unemployment rate. For instance, Horta et al. (2016) show that the rate of academic spin-off creation is positively associated with the skilled unemployment rate supporting the so-called recession push effect according to which when paid skilled jobs are less available, skilled entrepreneurs may be pushed toward self-employment. Although we do not have information on academic spin-off, we follow the Horta et al. (2016) intuition and consider the effect of the regional (NUTS 2 level) rate of unemployment of individuals between 15 and 74 years old collected from the European Statistical Office (EUROSTAST) in 2008 (the intermediate year of the period under study) on the firm’s propensity to develop innovations. Results (only the main specifications and the main variables proxing the research output of universities are reportedFootnote 8), summarized in Table 8, Models 3–7, are confirmed. Interestingly, the empirical evidence shows that the level of unemployment is negatively related to the firm’s propensity to develop new product and processes.

Table 8 Multiprobit regression. Marginal effects for all the dependent variables

We also examine the effect of the regional rate of unemployment on the firm’s probability of having as affiliates firms of which they own a share or at least 10% (as proxy of non-academic spin-offs).Footnote 9 Results (again only the main specifications and the main variables proxing the research output of universities are reportedFootnote 10) are summarized in Table 9, Models 3–7,Footnote 11 and show that the academic research indicator is not significant indicating the presence of no direct effects of the average research output on the firm’s propensity to establish spin-offs (Table 9, Models 3–5). However, when we differentiate local universities according to their research output (Table 9, Models 6–7), interestingly, the empirical evidence shows that especially the publications of the first-tier university are positive and statistically significant related to the likelihood of firms to create spin-offs. The rate of unemployment is confirmed to be negative and statistically significant, suggesting that a higher unemployment rate at the regional level will reduce the probability of spin-off creation. This result could be read in line with the idea that individuals are not incentivated to be pushed towards self-employment due to the risks brought by the lack of market demand and purchasing power of economies in which a substantial part of the population is unemployed.

Table 9 Multiprobit regression. Marginal effects for all the dependent variables

Secondly, with regard to the definition of local first-tier universities, the total number of Scopus publications may not be the best measure to take into consideration and a different result could be reached if the focus is only on publications that are strongly relevant to the manufacturing industry. An additional research output with industrial relevance could be, for instance, the number of patents owned by the university. Unfortunately, we do not have information on university patents for all the European countries included in our analysis. However, data on patents owned by Italian universities are instead available. Therefore, we repeat the analysis using the sub-sample of Italian firms in the dataset and use the number of patents owned by Italian universities, collected from the Italian Public Research Institutes (PATIRIS), as a proxy of research excellence. More specifically, we collect, for each university, the number of patents owned by the universities in the years 2007–2009. Then, the number of patents have been summed up at the NUTS3 level and matched with company-level data. Results, summarized in Table 10, Models 3–7, (again only the main specifications and the main variables proxing the research output of universities are reportedFootnote 12) show that academic patents have a direct impact on the firm’s propensity to develop product innovation (Table 10, Models 3–4). More specifically, when disentangling the contribution of the first-tier university from lower-tier institutions in term of patent production, the empirical evidence shows that academic patents at the first-tier university impacts product innovation more than that at lower-tier one (Table 10, Model 7) even though the result is only slightly statistically significant.

Table 10 Multiprobit regression. Marginal effects for all the dependent variables

Thirdly, we are aware that industrial sectors vary in terms of sources, paces and rates of technological change, which modulate firm requirements to be engaged in innovation networks, and the extent and character of such networking, university-based knowledge spillovers may be industry-specific (Bonaccorsi et al. 2013). Therefore, we also analyse the academic research indicator of the first-tier university vs that of all the other universities in the province by Pavitt macro-sector. Results (only for the main specification and the main variables proxing the research output of universitiesFootnote 13) are confirmed and presented, for all the dependent variables of the multiprobit regression and for each Pavitt macro-sector in Table 11, Models 6–7. More specifically, publications of both first- and lower-tier universities positively affect the university-firm collaboration when science-based firms are taken into account. Academic research at first-tier universities influences product innovation only of supplier-dominated industries. Furthermore, almost independently from the specific Pavitt classification, results confirm that publications has a detrimental effect on process innovation.

Table 11 Multiprobit regression. Marginal effects for all the dependent variables—Pavitt macro-sectors

Fourthly, concerning the proxies of academic productivity, it could be argued that the volume of publications does not properly account for the quality of the research. Although including quality indicators of academic research is not the aim of the paper, in order to take into account this issue we consider a further source of data such as the Global Research Benchmarking System (GRBS) data set, which is based on Scopus publications in 251 subject categories covering all science and technology fields. The data set includes universities that have published at least 50 papers in at least one subject category in the period 2007–2010 (Bonaccorsi et al. 2017).Footnote 14 From this data set, we sourced the total number of publications found in titles that are within the top 25 of that subject area based on the source-normalized impact per paper (SNIP) in 2010. This is a proxy of a selected volume of scientific publications (see Barra et al. 2019 where several indicators of academic quality have been considered among the contextual drivers of innovation). The number of publications associated with each university has been again summed up at the NUTS3 level and matched with company-level characteristics. The main results (again only the main specifications and the main variables proxing the research output of universities are reportedFootnote 15), summarized in Table 12 (Models 3–7), are confirmed. Indeed, the empirical evidence shows again that the academic research indicator is positive and statistically significant representing an important direct effect on product innovation (Table 12, Model 3–5). The publications of third-and further-tier universities increase firm’s propensity to develop product innovation while the publications of the first-tier universities are again negative and statistically significant having a detrimental effect on the development of process innovation (Table 12, Models 6–7).

Table 12 Multiprobit regression. Marginal effects for all the dependent variables

Finally, as previously discussed, in order to measure the research output of the academic institutions, we have used the number of publications, at the university level, collected from Scopus. However, to obtain an indicator of academic research output normalized by the output level of the university reaching the highest research output in the world, we also use the ARWU ranking. It is the first developed indicator of university world ranking and, among its components, it is possible to select one specifically referring to research output. Indeed, universities are ranked by several indicators of academic or research performance, including alumni winning Nobel Prizes and Fields Medals (proxy of the quality of education), staff winning Nobel Prizes and Fields Medals and highly cited researchers (proxies of the quality of the Faculty), papers published in Nature and Science and papers indexed in Science Citation Index-Expanded and Social Science Citation Index (proxies of the research output), and the per capita academic performance of an institution (proxy of the per capita performance). We focus on the ranking based on the research output criteria. According to this indicator, the highest scoring institution is assigned a score of 100, and other institutions are calculated as a percentage of the top score.Footnote 16 However, the Shanghai index ranks the universities up to the 500th position and we do not have any information on the specific ranking of institutions ranked above. Therefore, we have imputed the corresponding number of publications, previously collected from Scopus, to each university which is ranked above the 500th position. Then, we calculate the normalized output for each of these universities as the ratio of its Scopus publications to those of the university with the ARWU world highest score for research output criteria assigned in 2008. Again, all the information at university level have been summed up at the NUTS3 level and then matched with company-level characteristics.

Results (as the main findings are confirmed, we report only the main specification and the main variables proxing the research output of the universitiesFootnote 17) are summarised, for all the dependent variables of the multiprobit regression in Table 13, Models 3–7. The empirical evidence shows that the Shanghai index enhances the firm’s propensity to invest in intra muros R&D, to invest in R&D collaboration with universities or research labs as well as to develop product innovation (Table 13, Models 3–5). These results highlight that the number of Scopus publications is not the indicator of academic research firms use in their choice of R&D partners since the Shanghai index is significant.

Table 13 Multiprobit regression. Marginal effects for all the dependent variables

When we disaggregate the contribution of the first- and lower-tier universities, the empirical evidence confirms that academic research, as measured by the Shanghai index, of the third- and lower-tier universities is significant in the equation related to R&D university-firm collaboration (Table 13, Model 6 and 7). This result could be explained by the fact that lower-tier institutions might better meet firm’s needs. Especially when cutting-edge research is not involved, they are more likely to solve firm problems guaranteeing a more productive interaction between academics and the firm’s research teams. Further results are that academic research of the first-tier university, as measured by the Shanghai index, exerts a positive effect on firm’s propensity to develop product innovation whereas it is detrimental to the development of process innovation.

6 Concluding remarks

6.1 Conclusion

The aim of the paper is to empirically test the validity of four hypotheses. More specifically, we firstly examine whether the volume of academic research may enhance firm innovation differentiating local universities by research output level (H1). Secondly, we investigate whether research production at local second and third tier universities has the same of even greater knowledge spillover than that at local top-tier universities (H2). Thirdly, we explore if academic research may represent an alternative and important direct channel of technology transfer via informal relationship (H3). Finally, we also examine whether the role of education as a channel of university-based local knowledge spillovers may have been weakened due to a possible trade-off between university missions (H4).

In support of H1, results show that academic research has a direct impact on the firm’s propensity to develop innovation. When disentangling the contribution of the first-tier university from lower-tier institutions, the empirical evidence also shows that research at the second-tier university impacts product innovation more than that at first-tier one. Furthermore, the research output of the first-tier university exerts a detrimental effect on the development of process innovation whereas the research output of third- and lower-tier universities is beneficial. In favour of H2, this confirms that second-and third-tier universities may generate more knowledge spillovers than first-tier universities since their publications are associated with more innovation of local firms (Barra et al. 2019), being in line with the literature that suggests the possibility of a trade-off between university academic production and local knowledge spillovers useful for economic growth (Moscati et al. 2010; Perotti 2010). Results hold also when publications within the top 25 of that subject area as well as a different indicator of academic research output based on an international university ranking have been used. The empirical evidence validates the idea that beyond a certain threshold, firms may no longer consider the additional cost attached to collaboration with the local first-tier university worthwhile, as some first-tier universities may impose more stringent conditions than those imposed by lower-tier universities (see also Hong and Su 2013). This is also consistent with the idea that a trade-off exists between publications and informal collaboration with the industry (as previously suggested by Maietta 2015 and Maietta et al. 2017). More specifically, supporting H3, results show that the academic research indicator is positive and statistically significant meaning an important direct effect on product innovation, catching the effect of academic knowledge spillovers through informal relationships, informal contacts or direct interactions between academics and firms. Furthermore, informal participation in collaborative activities may be lower in first-tier universities since academics working in lower-tier universities have higher incentive to build these collaborations with firms to fund their own research activities (see Perkmann et al. 2013). Finally, in favour of H4, education does not seem to act as a channel of local knowledge spillovers suggesting that the pressure to publish on international journals to reach a good research assessment may have decreased the quality of teaching up to the point of weakening the role of education as a channel of local knowledge spillovers.

6.2 Discussion and implications

Several limitations as well as future lines of research can be derived from our analyses.

A first limitation of the analysis is related to data constraints. Indeed, the empirical evidence is based on data that exclude micro-sized firms (with less than 10 workers). Secondly, as argued in the theoretical background highlighted in Sects. 1 and 2, the role of education as a channel of university-based local knowledge spillovers may have been weakened as a consequence of the changes occurred over the last decades in the European universities. We proxy the education activities with the number of national and international students of the universities within the province where the university is located. We are aware that the number of students does not fully and perfectly represent the amount of teaching workload of universities. Indeed, knowledge spillovers from universities to firms may also operate through an upgrading of human capital stock in the area where the university is located. Incorporating in the empirical model the university graduates for all the European higher education institutions may help in disentangling education as a channel of local university-based knowledge spillovers. An additional limitation is related to the definition of local first-tier universities as the total number of publications are not the only measure of the volume of a university’s research production. More work is needed to consider different proxies in terms of research output with industrial relevance. Finally, the use of Scopus publications has also potential limitations. It could indeed be possible that some papers that are particularly important for local firms could have been published in regional or national academic journals, which are not necessarily included in Scopus. And given that an important goal of the paper is to examine the role of publications on local innovation, this could be an important shortcoming, being particularly relevant in social sciences and humanities, where academic knowledge is often published in outlets that are not included in Scopus, or even in books and non-academic reports.

Our research opens the way to future interesting extensions. One immediate extension would be to test the role played by the context in which the firm operates-in terms of the quality of institutions—and assess the connection between regional quality of government and the university-firm relationship.

Several implications can also be derived from our analysis.

Firstly, our results suggest the importance of research carried out also by the lower-tier university. Therefore policies that aim at fostering academic research in Europe can be beneficial to raise the overall level of absorptive capacity innovation systems. But this should not be done reducing the resources devoted to lower-output institutions given their importance in sustaining local-level opportunities. On the other hand, in order to force first-tier universities to interact with local firms, incentives for university-firm collaboration may be increased in case of collaboration between the first-tier university and a local firm.

Secondly, a trade-off between university missions, particularly between academic production, as measured by the number of publications in academic journals versus local knowledge spillovers due to a change in the incentive structure may exists. Indeed, acts conducive to knowledge spillovers may not be particularly rewarded in academia when career advancement is predominantly dictated by scholar research quality. Consequently, researchers, mainly those employed in virtuous universities, will be more focused on high-ranked journal publications to increase their own reputation. In such circumstances, consultancies or informal collaboration may be too time demanding, and scholars may tend to concentrate on less industry-oriented academic publications. The empirical evidence partly supports this hypothesis showing that the volume of academic research, especially in lower tier universities, has an important direct impact on the firm’s propensity to develop innovation.

In conclusion, research production, although very important, is not sufficient to explain university-based knowledge spillovers. It may be the case that academic research may enhance radical innovation of relatively few firms working on cutting-edge research, whereas less advanced academic research may be directly useful to incremental innovation of most local firms. Scientific research and its market exploitation may be helpful to each other since academic researchers cooperating in firms’ projects acquire resources that are useful for future research. This incentive may motivate particularly high-performing academics working in lower ranked institutions, where fewer financial resources are available, as these scholars are more likely to be involved in collaborative research and industry networking (Perkmann et al. 2013).