Abstract
The transplantation of hepatocytes could be an alternative therapeutic option to the whole organ transplantation for the treatment of end-stage liver diseases. However, this cell-based therapy needs the understanding of the molecular mechanisms to improve efficacy. This chapter includes a detailed method of a rat model for liver regeneration studies after age-dependent hepatocyte transplantation.
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Acknowledgement
The author would like to thank Madlen Hempel for her excellent technical assistance.
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Stock, P. (2014). Age-Dependent Hepatocyte Transplantation for Functional Liver Tissue Reconstitution. In: Christ, B., Oerlecke, J., Stock, P. (eds) Animal Models for Stem Cell Therapy. Methods in Molecular Biology, vol 1213. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-1453-1_4
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DOI: https://doi.org/10.1007/978-1-4939-1453-1_4
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