Abstract
Purpose
We evaluated the effects of the peeling of the internal limiting membrane (ILM) during vitrectomy in diabetic cystoid macular edema (CME) patients.
Methods
Visual outcome and intraoperative and postoperative complications were evaluated retrospectively in 84 CME patients (100 eyes), all of whom had been followed for at least 1 year postoperatively. Before January 2001, we did not perform ILM peeling at our hospitals; 57 patients (66 eyes) treated before 2001 were included in this retrospective study as the non-peeling group. After January 2001, ILM peeling was performed in 27 (34 eyes) CME patients, who were included in this study as the peeling group. In the peeling group, indocyanine green (ICG) staining was performed at the time of ILM peeling.
Results
Visual acuity improved significantly after vitrectomy regardless of ILM peeling. Visual acuity improved gradually from 6 months to 1 year after the operation, and improved further at the final observation point in both groups. Visual acuity did not differ significantly between the two groups at any time point. There was no difference in the incidence of intraoperative and postoperative complications between the two groups. There were no adverse events associated with ICG-assisted ILM peeling.
Conclusions
Visual acuity improved with vitrectomy for diabetic cystoid macular edema in both groups. ILM peeling was not found to improve visual acuity postoperatively. Jpn J Ophthalmol 2005;49:297–300 © Japanese Ophthalmological Society 2005
Article PDF
Similar content being viewed by others
Avoid common mistakes on your manuscript.
References
H Lewis GW Abrams MS Blumenkranz RV Campo (1992) ArticleTitleVitrectomy for diabetic macular traction and edema associated with posterior hyaloidal traction Ophthalmology 99 753–759 Occurrence Handle1594222
N Tachi N Ogino (1994) ArticleTitleVitrectomy for diffuse macular edema associated with diabetic retinopathy Atarashii Ganka (J Eye) 11 1077–1081
T Yamamoto S Yamamoto S Takeuchi (2000) ArticleTitlePars plana vitrectomy for diabetic macular edema with posterior vitreous detachment Atarashii Ganka (J Eye) 17 133–138
Y Sato Z Lee H Shimada (2002) ArticleTitleVitrectomy for diabetic cystoid macular edema Jpn J Ophthalmol 46 315–322 Occurrence Handle10.1016/S0021-5155(02)00471-9 Occurrence Handle12063043
N Tachi (1994) ArticleTitleVitrectomy for macular edema. Ganka Shujutsu J Jpn Ophthalmic Surg 7 407–414
A Gandorfer EM Messmer MW Ulbig A Kampik (2000) ArticleTitleResolution of diabetic macular edema after surgical removal of the posterior hyaloid and the inner limiting membrane Retina 20 126–133 Occurrence Handle10.1097/00006982-200003000-00003 Occurrence Handle10783944
AV Ljubimov RE Burgeson RJ Butkowski et al. (1996) ArticleTitleBasement membrane abnormalities in human eyes with diabetic retinopathy J Histochem Cytochem 44 1469–1479 Occurrence Handle8985139
T Yamamoto (2003) ArticleTitleVitrectomy for diabetic macular edema—new horizon in vitrectomy Atarashii Ganka (J Eye) 20 903–907
K Kumagai N Ogino M Furukawa et al. (2002) ArticleTitleInternal limiting membrane peeling in vitreous surgery for diabetic macular edema Nippon Ganka Gakkai Zasshi (J Jpn Ophthalmol Soc) 106 590–594
T Tamura A Hirakata H Oda et al. (2003) ArticleTitleOutcome of vitreous surgery with internal limiting membrane peeling for diabetic macular edema Ganka Rinsho Iho (Jpn Rev Clin Ophthalmol) 97 979–982
T Gotoh M Imai H Iijima (2003) ArticleTitleEffect of peeling the internal limiting membrane for diabetic macular edema Nihon Ganka Kiyo (Folia Ophthalmol Jpn) 54 109–112
K Kadonosono N Itoh E Uchio et al. (2000) ArticleTitleStaining of internal limiting membrane in macular hole surgery Arch Ophthalmol 118 1116–1118 Occurrence Handle10922208
C Haritoglou A Gandorfer CA Gass et al. (2002) ArticleTitleIndocyanine green-assisted peeling of the internal limiting membrane in macular hole surgery affects visual outcome: a clinicopathologic correlation Am J Ophthalmol 134 836–841 Occurrence Handle10.1016/S0002-9394(02)01816-0 Occurrence Handle12470751
K Kumagai N Ogino S Demizu et al. (2000) ArticleTitleFoveal thickness and retinal sensitivity following surgery for idiopathic epiretinal membrane. Rinsho Ganka Jpn J Clin Ophthalmol 54 59–62
H Terasaki Y Miyake R Nomura et al. (2001) ArticleTitleFocal macular ERGs in eyes after removal of macular ILM during macular hole surgery Invest Ophthalmol Vis Sci 42 229–234 Occurrence Handle11133873
F Ishikawa N Ogino K Okita et al. (2001) ArticleTitleRetinal nerve fiber layer defect after vitrectomy and internal limiting membrane peeling for idiopathic macular hole and epiretinal membrane. Rinsho Ganka Jpn J Clin Ophthalmol 55 1539–1544
M Ashikari M Nozaki M Kojima Y Ogura (2001) ArticleTitleOutcome of removal of internal limiting membrane with adjunct use of indocyanine green. Rinsho Ganka Jpn J Clin Ophthalmol 55 863–866
K Sonoda T Sakamoto H Enaida et al. (2004) ArticleTitleResidual vitreous cortex after surgical posterior vitreous separation visualized by intravitreous triamcinolone acetonide Ophthalmology 111 226–230 Occurrence Handle10.1016/j.ophtha.2003.05.034 Occurrence Handle15019367
Author information
Authors and Affiliations
Corresponding author
About this article
Cite this article
Kamura, Y., Sato, Y., Isomae, T. et al. Effects of Internal Limiting Membrane Peeling in Vitrectomy on Diabetic Cystoid Macular Edema Patients. Jpn J Ophthalmol 49, 297–300 (2005). https://doi.org/10.1007/s10384-005-0199-7
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/s10384-005-0199-7