Abstract
Avoidance of secondary cerebral hypoxia/ischemia is a mainstay of therapy in neurocritical care. On-line monitoring of brain tissue oxygen tension (PbtO2) enables detection of secondary brain hypoxic/ischemic insults and targeting of therapeutic interventions, such as intracranial pressure (ICP) control, cerebral perfusion pressure (CPP) augmentation, blood transfusion, and ventilation. Emerging evidence shows that compared to standard ICP/CPP management, PbtO2-directed therapy may improve outcomes of selected populations of brain-injured patients. Larger prospective multicenter trials are underway to further evaluate the potential benefit of PbtO2-directed therapy.
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Keywords
- Traumatic Brain Injury
- Cerebral Perfusion Pressure
- Severe Traumatic Brain Injury
- Brain Hypoxia
- Brain Oxygen
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Geukens, P., Oddo, M. (2012). Brain Tissue Oxygen Monitoring in Neurocritical Care. In: Vincent, JL. (eds) Annual Update in Intensive Care and Emergency Medicine 2012. Annual Update in Intensive Care and Emergency Medicine, vol 2012. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-25716-2_66
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DOI: https://doi.org/10.1007/978-3-642-25716-2_66
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