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Development of New Refrigeration System and Optimum Geometry of the Vapor Condenser for Pharmaceutical Freeze Dryers

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Drying ’85

Abstract

Features of a new refrigeration system called “Triple Heat Exchange Trap” system are that an array of the vapor condenser plates serves as a heat exchanger with three effects: heat transfer between water vapor and refrigerant(1), between water vapor and brine(2), and between refrigerant and brine(3). The condenser plate array also acts as brine cooler for shelf cooling. Since its development in 1980, this new system has been employed for more than 60 sets of phermaceutical freeze dryers, ensuring accurate temperature control, stabilized operation and high efficiency. In observing ice build-up patterns on the condenser and deterioration of the condenser capability through ice building, it was confirmed that comparing the observations with simplified mathematical model, both experimental and theoretical values are nearly equal.

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References

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© 1985 Springer-Verlag Berlin Heidelberg

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Kobayashi, M. (1985). Development of New Refrigeration System and Optimum Geometry of the Vapor Condenser for Pharmaceutical Freeze Dryers. In: Toei, R., Mujumdar, A.S. (eds) Drying ’85. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-21830-3_36

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  • DOI: https://doi.org/10.1007/978-3-662-21830-3_36

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-21832-7

  • Online ISBN: 978-3-662-21830-3

  • eBook Packages: Springer Book Archive

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