Abstract
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Salivary gland lesions are rare and can be pathologically challenging due to their wide morphologic spectra.
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Non-neoplastic diseases
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Acute and chronic non-autoimmune sialadenitis each have fairly characteristic pathologic features though they may have a variety of etiologic factors and pathogenetic mechanisms.
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Autoimmune sialadenitis is largely comprised of the myoepithelial sialadenitis seen in Sjögren’s syndrome, though several autoimmune diseases may manifest in the salivary gland. A complication may be B-cell lymphoproliferative disorders. A subset of chronic sclerosing sialadenitis belongs to this group of diseases.
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Necrotizing sialometaplasia is a benign selflimited process that may histologically mimic squamous cell carcinoma or mucoepidermoid carcinoma. Subacute necrotizing sialadenitis is a relatively newly described related entity.
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Sialadenosis is a manifestation of generalized metabolic disturbances while adenomatoid hyperplasia is often an incidental finding.
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Salivary lymphoepithelial cysts of the salivary gland include salivary type, first branchial cleft cysts, and lymphoepithelial cystic disease of HIV. Dysgenetic polycystic disease is an extremely rare entity.
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Benign tumors
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Pleomorphic adenomas are the most common benign tumors and have a broad histologic spectrum. These tumors can recur if incompletely excised and may rarely metastasize without having histologic features of malignancy.
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Basal cell adenomas are benign tumors with specific histologic patterns. The membranous type is associated with cylindromatosis gene (CYLD1) mutations, cutaneous syndromes, and can be multifocal and is more likely to undergo malignant transformation. Canalicular adenomas are minor salivary tumors that are clinicopathologically distinct from basal cell adenomas.
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Myoepitheliomas also have varied patterns and should show at most a few ducts.
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Warthin’s tumor is linked to smoking and older age and is thus demographically distinct from other cystadenomas. Morphologically it has a characteristic lymphoid stroma resembling a lymph node.
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Oncocytoma and oncocytosis are benign tumors and tumor-like lesions comprised of solid nests of large polygonal cells with abundant granular eosinophilic cytoplasm that may occasionally mimic metastatic renal cell carcinoma.
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Sclerosing polycystic adenosis is a rare clonal proliferation that resembles fibrocystic disease of the breast, and though benign, may show changes resembling salivary duct carcinoma.
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Malignant tumors
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Adenoid cystic carcinoma is a slow growing but relentless malignancy for which stage, histologic grade based on solid component, and p53 expression are important prognosticators. These characteristically overexpress c-kit.
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Mucoepidermoid carcinoma is the most common salivary malignancy with three cell types (mucous, intermediate, and epidermoid). Most grading systems are three tiered and generally correlate with prognosis; mucoepidermoid carcinomas of the submandibular gland appear more aggressive than those of the parotid gland.
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Malignant mixed tumors can be subcategorized into carcinoma ex-pleomorphic adenoma, true malignant mixed tumor (carcinosarcoma), and metastasizing mixed tumor.
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Acinic cell carcinoma is a low-grade tumor that can rarely dedifferentiate into an aggressive high grade tumor.
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Epithelial-myoepithelial carcinoma is a rare biphasic low-grade neoplasm characterized by clear myoepithelial cells and small ducts and may mimic other clear cell lesions of the head and neck.
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Basal cell adenocarcinoma resembles its benign counterpart, basal cell adenoma, and is distinguished mainly by the presence of invasion, though ancillary studies such as immunoperoxidase stains for Ki 67, p53, bc1-2, and epidermal growth factor receptor may help in diagnosis.
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Myoepithelial carcinoma also resembles its benign counterpart and is separated mainly by the presence of invasion, mitoses, and necrosis. Nuclear pleomorphism may be a poor prognostic sign.
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Salivary duct carcinoma is a high grade carcinoma that expresses androgen receptor and her-2-neu. It can be confused with low-grade cribriform cystadenocarcinoma, a recently characterized entity that resembles a lowgrade mammary type ductal carcinoma.
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Rare malignant tumors include cystadenocarcinomas, large cell carcinoma, small cell carcinoma, and primary squamous cell carcinomas; all but cystadenocarcinomas behave in an aggressive fashion.
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References
Abbondanzo SL (2001) Extranodal marginal-zone Bcell lymphoma of the salivary gland. Ann Diagn Pathol 5:246–254
Aberle AM, Abrams AM, Bowe R, et al. (1985) Lobular (polymorphous low-grade) carcinoma of minor salivary glands. A clinicopathologic study of twenty cases. Oral Surg Oral Med Oral Pathol 60:387–395
Abrams AM, Melrose RJ, Howell FV (1973) Necrotizing sialometaplasia. A disease simulating malignancy. Cancer 32:130–135
Aframian D, Milhem II, Kirsch G, et al. (1995) Necrotizing Sialometaplasia after Silastic Ring Vertical Gastroplasty: Case Report and Review of Literature. Obes Surg 5:179–182
Ahn MS, Hayashi GM, Hilsinger RL Jr., et al. (1999) Familial mixed tumors of the parotid gland. Head Neck 21:772–775
Albores-Saavedra J, Morris AW (1963) Sebaceous adenoma of the submaxillary salivary gland. Report of a case. Arch Otolaryngol 77:500–503
Alcedo JC, Fabrega JM, Arosemena JR, et al. (2004) Imatinib mesylate as treatment for adenoid cystic carcinoma of the salivary glands: report of two successfully treated cases. Head Neck 26:829–831
Alho OP, Kristo A, Luotonen J, et al. (1996) Intraductal papilloma as a cause of a parotid duct cyst. A case report. J Laryngol Otol 110:277–278
Allen MS Jr., Fitz-Hugh GS, Marsh WL Jr. (1974) Low-grade papillary adenocarcinoma of the palate. Cancer 33:153–158
Alos L, Cardesa A, Bombi JA, et al. (1996) Myoepithelial tumors of salivary glands: a clinicopathologic, immunohistochemical, ultrastructural, and flow-cytometric study. Semin Diagn Pathol 13:138–147
Alos L, Lujan B, Castillo M, et al. (2005) Expression of membrane-bound mucins (MUC1 and MUC4) and secreted mucins (MUC2, MUC5AC, MUC5B, MUC6 and MUC7) in mucoepidermoid carcinomas of salivary glands. Am J Surg Pathol 29:806–813
Alvarez-Canas C, Rodilla IG (1996) True malignant mixed tumor (carcinosarcoma) of the parotid gland. Report of a case with immunohistochemical study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 81:454–458
Anderson C, Muller R, Piorkowski R, et al. (1992) Intraductal carcinoma of major salivary gland. Cancer 69:609–614
Andreadis D, Epivatianos A, Poulopoulos A, et al. (2006) Detection of C-KIT (CD117) molecule in benign and malignant salivary gland tumours. Oral Oncol 42:57–65
Andreadis D, Nomikos A, Epivatianos A, et al. (2005) Basaloid squamous cell carcinoma versus basal cell adenocarcinoma of the oral cavity. Pathology 37:560–563
Arafat A, Brannon RB, Ellis GL (1981) Adenomatoid hyperplasia of mucous salivary glands. Oral Surg Oral Med Oral Pathol 52:51–55
Arida M, Barnes EL, Hunt JL (2005) Molecular assessment of allelic loss in Warthin tumors. Mod Pathol 18:964–968
Aronsohn RS, Batsakis JG, Rice DH, et al. (1976) Anomalies of the first branchial cleft. Arch Otolaryngol 102:737–740
Arriaga MA, Myers EN (1990) The surgical management of chronic parotitis. Laryngoscope 100:1270–1275
Assor D (1970) Sebaceous lymphadenoma of the parotid gland. A case report. Am J Clin Pathol 53:100–103
Attie JN, Sciubba JJ (1981) Tumors of major and minor salivary glands: clinical and pathologic features. Curr Probl Surg 18:130–133
Auclair PL (1994) Tumor-associated lymphoid proliferation in the parotid gland. A potential diagnostic pitfall. Oral Surg Oral Med Oral Pathol 77:19–26
Auclair PL, Ellis GL (1991) Primary squamous cell carcinoma Surgical pathology of the salivary glands. Edited by Ellis GL, Auclair PL, Gnepp DR. Philadelphia, WB Saunders Co., pp 369–378
Auclair PL, Ellis GL (1996) Atypical features in salivary gland mixed tumors: their relationship to malignant transformation. Mod Pathol 9:652–657
Avitia S, Hamilton JS, Osborne RF (2005) Epithelial-myoepithelial carcinoma. Ear Nose Throat J 84:764, 767
Aydin O, Yilmaz T, Ozer F, et al. (2002) Necrotizing sialometaplasia of parotid gland: a possible vasculitic cause. Int J Pediatr Otorhinolaryngol 64:171–174
Aydm E, Turkoglu S, Ozen O, et al. (2005) Mucinous cystadenocarcinoma of a minor salivary gland in the upper lip: Case report. Auris Nasus Larynx 32:301–304
Ayoub OM, Bhatia K, Mal RK (2002) Pleomorphic adenoma of the parotid gland: is long-term follow-up needed? Auris Nasus Larynx 29:283–285
Azevedo LR, Damante JH, Lara VS, et al. (2005) Age-related changes in human sublingual glands: a post mortem study. Arch Oral Biol 50:565–574
Azumi N, Battifora H (1987) The cellular composition of adenoid cystic carcinoma. An immunohistochemical study. Cancer 60:1589–1598
Azzopardi JG, Evans DJ (1971) Malignant lymphoma of parotid associated with Mikulicz disease (benign lymphoepithelial lesion). J Clin Pathol 24:744–752
Bahler DW, Swerdlow SH (1998) Clonal salivary gland infiltrates associated with myoepithelial sialadenitis (Sjogren’s syndrome) begin as nonmalignant antigen-selected expansions. Blood 91:1864–1872
Balogh K, Wolbarsht RL, Federman M, et al. (1985) Carcinoma of the parotid gland with osteoclastlike giant cells. Immunohistochemical and ultrastructural observations. Arch Pathol Lab Med 109:756–761
Baratz M, Loewenthal M, Rozin M (1976) Sebaceous lymphadenoma of the parotid gland. Arch Pathol Lab Med 100:269–270
Barnes L, Appel B, Perez H, et al. (1985) Myoepitheliomas of the head and neck: Case report and review. J Surg Oncol 28:21–28
Barnes L, Appel BN, Perez H, et al. (1985) Myoepithelioma of the head and neck: case report and review. J Surg Oncol 28:21–28
Barnes L, Rao U, Contis L, et al. (1994) Salivary duct carcinoma. Part II. Immunohistochemical evaluation of 13 cases for estrogen and progesterone receptors, cathepsin D, and cerbB-2 protein. Oral Surg Oral Med Oral Pathol 78:74–80
Barnes L, Rao U, Krause J, et al. (1994) Salivary duct carcinoma. Part I. A clinicopathologic evaluation and DNA image analysis of 13 cases with review of the literature. Oral Surg Oral Med Oral Pathol 78:64–73
Barrett AW, Speight PM (1995) Adenomatoid hyperplasia of oral minor salivary glands. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 79:482–487
Batsakis J (1979) Tumors of the Head and Neck. Clinical and Pathological Considerations, 2nd edition. Baltimore, Williams and Wilkins and Wilkins Co., pp 26–30
Batsakis JG (1982) Malignant mixed tumor. Ann Otol Rhinol Laryngol 91:342–343
Batsakis JG (1983) Primary squamous cell carcinomas of major salivary glands. Ann Otol Rhinol Laryngol 92:97–98
Batsakis JG (1991) Sublingual gland. Ann Otol Rhinol Laryngol 100:521–522
Batsakis JG, Bernacki EG, Rice DH, et al. (1975) Malignancy and the benign lymphoepithelial lesion. Laryngoscope 85:389–399
Batsakis JG, Bruner JM, Luna MA (1988) Polycystic (dysgenetic) disease of the parotid glands. Arch Otolaryngol Head Neck Surg 114:1146–1148
Batsakis JG, Chinn E, Regezi JA, et al. (1978) The pathology of head and neck tumors: salivary glands, part 2. Head Neck Surg 1:167–180
Batsakis JG, Chinn EK, Weimert TA, et al. (1979) Acinic cell carcinoma: a clinicopathologic study of thirty-five cases. J Laryngol Otol 93:325–340
Batsakis JG, el-Naggar AK (1991) Terminal duct adenocarcinomas of salivary tissues. Ann Otol Rhinol Laryngol 100:251–253
Batsakis JG, el-Naggar AK, Luna MA (1992) Epithelialmyoepithelial carcinoma of salivary glands. Ann Otol Rhinol Laryngol 101:540–542
Batsakis JG, Kraemer B, Sciubba JJ (1983) The pathology of head and neck tumors: the myoepithelial cell and its participation in salivary gland neoplasia, Part 17. Head Neck Surg 5:222–233
Batsakis JG, Luna MA (1990) Histopathologic grading of salivary gland neoplasms: I. Mucoepidermoid carcinomas. Ann Otol Rhinol Laryngol, 99:835–838
Batsakis JG, Luna MA (1991) Basaloid salivary carcinoma. Ann Otol Rhinol Laryngol 100:785–787
Batsakis JG, Luna MA (1991) Undifferentiated carcinomas of salivary glands. Ann Otol Rhinol Laryngol 100:82–84
Batsakis JG, Luna MA, el-Naggar A (1990) Histopathologic grading of salivary gland neoplasms: III. Adenoid cystic carcinomas. Ann Otol Rhinol Laryngol 99:1007–1009
Batsakis JG, Pinkston GR, Luna MA, et al. (1983) Adenocarcinomas of the oral cavity: a clinicopathologic study of terminal duct carcinomas. J Laryngol Otol 97:825–835
Batsakis JG, Raymond AK (1989) Sialocysts of the parotid glands. Ann Otol Rhinol Laryngol 98:487–489
Batsakis JG, Regezi JA (1978) The pathology of head and neck tumors: salivary glands, part 1. Head Neck Surg 1:59–68
Batsakis JG, Wozniak KJ, Regezi JA (1977) Acinous cell carcinoma: a histogenetic hypothesis. J Oral Surg 35:904–906
Baugh RF, Wolf GT, McClatchey KD (1986) Small cell carcinoma of the head and neck. Head Neck Surg 8:343–354
Baurmash HD (2004) Chronic recurrent parotitis: a closer look at its origin, diagnosis, and management. J Oral Maxillofac Surg 62:1010–1018
Beahrs OH, Woolner LB, Kirklin JW, et al. (1957) Carcinomatous transformation of mixed tumors of the parotid gland. AMA Arch Surg, 75:605–613; discussion 613–604
Begin LR, Black MJ (1993) Salivary-type myxoid myoepithelioma of the sinonasal tract: a potential diagnostic pitfall. Histopathology 23:283–285
Begin LR, Rochon L, Frenkiel S (1991) Spindle cell myoepithelioma of the nasal cavity. Am J Surg Pathol 15:184–190
Beltran D, Faquin WC, Gallagher G, et al. (2006) Selective immunohistochemical comparison of polymorphous lowgrade adenocarcinoma and adenoid cystic carcinoma. J Oral Maxillofac Surg 64:415–423
Berean KW, Watts MC, Mills SE (1995) Basal cell adenocarcinoma of salivary glands. Lab Invest 72:99A
Bhalla RK, Jones TM, Taylor W, et al. (2002) Carcinosarcoma (malignant mixed tumor) of the submandibular gland: A case report and review of the literature. J Oral Maxillofac Surg 60:1067–1069
Bharadwaj G, Nawroz I, O’Regan B (2007) Sclerosing polycystic adenosis of the parotid gland. Br J Oral Maxillofac Surg 45:74–76
Billroth T (1859) Beobachtungen Uber Geschwulste der Speichisdrusen Virch. Pathol Anat 17:357–375
Blanck C, Eneroth CM, Jakobsson PA (1971) Mucus-producing adenopapillary (non-epidermoid) carcinoma of the parotid gland. Cancer 28:676–685
Bleiweiss IJ, Huvos AG, Lara J, et al. (1992) Carcinosarcoma of the submandibular salivary gland. Immunohistochemical findings. Cancer 69:2031–2035
Boahene DK, Olsen KD, Lewis JE, et al. (2004) Mucoepidermoid carcinoma of the parotid gland: the Mayo clinic experience. Arch Otolaryngol Head Neck Surg 130:849–856
Boles R, Johns ME, Batsakis JG (1973) Carcinoma in pleomorphic adenomas of salivary glands. Ann Otol Rhinol Laryngol 82:684–690
Bombi JA, Alos L, Rey MJ, et al. (1996) Myoepithelial carcinoma arising in a benign myoepithelioma: immunohistochemical, ultrastructural, and flow-cytometrical study. Ultrastruct Pathol 20:145–154
Bos I, Meyer S, Merz H (2004) [Lymphadenoma of the parotid gland without sebaceous differentiation. Immunohistochemical investigations]. Pathologe 25:73–78
Bowman SJ (2002) Collaborative research into outcome measures in Sjogren’s syndrome. Update on disease assessment. Scand J Rheumatol Suppl (116):23–27
Bradley P (2005) Metastasizing pleomorphic salivary adenoma should now be considered a low grade malignancy with a lethal potential. Otolaryngol Head Neck Surg 13:123–126
Bradley PJ (2004) Adenoid cystic carcinoma of the head and neck: a review. Curr Opin Otolaryngol Head Neck Surg 12:127–132
Bradley PJ (2005) Metastasizing pleomorphic salivary adenoma should now be considered a low-grade malignancy with a lethal potential. Curr Opin Otolaryngol Head Neck Surg 13:123–126
Brandwein-Gensler M, Hille J, Wang BY, et al. (2004) Lowgrade salivary duct carcinoma: description of 16 cases. Am J Surg Pathol 28:1040–1044
Brandwein M, Huvos A (1995) Laryngeal oncocytic cystadenomas. Eight cases and a literature review. Arch Otolaryngol Head Neck Surg 121:1302–1305
Brandwein M, Huvos AG, Dardick I, et al. (1996) Noninvasive and minimally invasive carcinoma ex mixed tumor: a clinicopathologic and ploidy study of 12 patients with major salivary tumors of low (or no?) malignant potential. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 81:655–664
Brandwein MS, Huvos AG (1991) Oncocytic tumors of major salivary glands. A study of 68 cases with follow-up of 44 patients. Am J Surg Pathol 15:514–528
Brandwein MS, Ivanov K, Wallace DI, et al. (2001) Mucoepidermoid carcinoma: a clinicopathologic study of 80 patients with special reference to histological grading. Am J Surg Pathol 25:835–845
Brandwein MS, Jagirdar J, Patil J, et al. (1990) Salivary duct carcinoma (cribriform salivary carcinoma of excretory ducts). A clinicopathologic and immunohistochemical study of 12 cases. Cancer 65:2307–2314
Brannon RB, Fowler CB, Hartman KS (1991) Necrotizing sialometaplasia. A clinicopathologic study of sixty-nine cases and review of the literature. Oral Surg Oral Med Oral Pathol 72:317–325
Brannon RB, Houston GD, Meader CL (1985) Adenomatoid hyperplasia of mucous salivary glands: a case involving the retromolar area. Oral Surg Oral Med Oral Pathol 60:188–190
Brannon RB, Sciubba JJ, Giulani M (2001) Ductal papillomas of salivary gland origin: A report of 19 cases and a review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 92:68–77
Brannon RB, Willard CC (2003) Oncocytic mucoepidermoid carcinoma of parotid gland origin. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 96:727–733
Brauneis J, Laskawi R, Schroder M, et al. (1990) [Squamous cell carcinoma in the area of the parotid gland. Metastasis or primary tumor?]. HNO 38:292–294
Brehmer D, Hohbach M, Laubert A (1999) [Intraductal papilloma of the parotid gland]. Laryngorhinootologie 78:332–334
Brook I (2003) Acute bacterial suppurative parotitis: microbiology and management. J Craniofac Surg 14:37–40
Browand BC, Waldron CA (1975) Central mucoepidermoid tumors of the jaws. Report of nine cases and review of the literature. Oral Surg Oral Med Oral Pathol 40:631–643
Bruner JM, Cleary KR, Smith FB, et al. (1989) Immunocytochemical identification of HIV (p24) antigen in parotid lymphoid lesions. J Laryngol Otol 103:1063–1066
Buchholz TA, Shimotakahara SG, Weymuller EA Jr., et al. (1993) Neutron radiotherapy for adenoid cystic carcinoma of the head and neck. Arch Otolaryngol Head Neck Surg 119:747–752
Buchner A, Merrell PW, Carpenter WM, et al. (1991) Adenomatoid hyperplasia of minor salivary glands. Oral Surg Oral Med Oral Pathol 71:583–587
Buenting JE, Smith TL, Holmes DK (1998) Giant pleomorphic adenoma of the parotid gland: case report and review of the literature. Ear Nose Throat J 77:637–640
Bullerdiek J, Wobst G, Meyer-Bolte K, et al. (1993) Cytogenetic subtyping of 220 salivary gland pleomorphic adenomas: correlation to occurrence, histological subtype, and in vitro cellular behavior. Cancer Genet Cytogenet 65:27–31
Buxton RW, Maxwell JH, French AJ (1953) Surgical treatment of epithelial tumors of the parotid gland. Surg Gynecol Obstet 97:401–416
Cabov T, Macan D, Manojlovic S, et al. (2004) Oral inverted ductal papilloma. Br J Oral Maxillofac Surg 42:75–77
Capone RB, Ha PK, Westra WH, et al. (2002) Oncocytic neoplasms of the parotid gland: a 16-year institutional review. Otolaryngol Head Neck Surg 126:657–662
Cardesa A, Alos L (2005) Myoepithelioma. Pathology and Classification of Head and Neck Tumours. Edited by Barnes EL, Eveson JW, Reichart P, Sidransky D. Lyon, IARC, pp 259–260
Carew JF, Spiro RH, Singh B, et al. (1999) Treatment of recurrent pleomorphic adenomas of the parotid gland. Otolaryngol Head Neck Surg 121:539–542
Caselitz J, Schulze I, Seifert G (1986) Adenoid cystic carcinoma of the salivary glands: an immunohistochemical study. J Oral Pathol 15:308–318
Casler JD, Conley JJ (1992) Surgical management of adenoid cystic carcinoma in the parotid gland. Otolaryngol Head Neck Surg 106:332–338
Castle JT, Thompson LD, Frommelt RA, et al. (1999) Polymorphous low grade adenocarcinoma: a clinicopathologic study of 164 cases. Cancer 86:207–219
Castro WH, Drummond SN, Gomez RS (2002) Subacute necrotizing sialadenitis in the buccal mucosa. J Oral Maxillofac Surg 60:1494–1496
Chan JK, Saw D (1987) Sclerosing mucoepidermoid tumour of the parotid gland: report of a case. Histopathology 11:203–207
Chan JK, Suster S, Wenig BM, et al. (1997) Cytokeratin 20 immunoreactivity distinguishes Merkel cell (primary cutaneous neuroendocrine) carcinomas and salivary gland small cell carcinomas from small cell carcinomas of various sites. Am J Surg Pathol 21:226–234
Chang A, Harawi SJ (1992) Oncocytes, oncocytosis, and oncocytic tumors. Pathol Annu 27 Pt 1:263–304
Chang JY, Hsiao CH (2004) Lymphadenoma lacking sebaceous differentiation in the parotid gland. J Formos Med Assoc 103:459–462
Chaplin AJ, Darke P, Patel S (1983) Tyrosine-rich crystals in pleomorphic adenomas of parotid glands. J Oral Pathol 12:342–346
Chaudhry AP, Vickers RA, Gorlin RJ (1961) Intraoral minor salivary gland tumors: An analysis of 1,414 cases. Oral Surg Oral Med Oral Path 14:1194–1226
Chen I, Tu H (2000) Pleomorphic adenoma of the parotid gland metastasizing to the cervical lymph node. Otolaryngol Head Neck Surg 122:455–457
Chen JC, Gnepp DR, Bedrossian CW (1988) Adenoid cystic carcinoma of the salivary glands: an immunohistochemical analysis. Oral Surg Oral Med Oral Pathol 65:316–326
Chen KT (1985) Carcinoma arising in monomorphic adenoma of the salivary gland. Am J Otolaryngol 6:39–41
Chen YK, Lin CC, Lin LM, et al. (1999) Adenomatoid hyperplasia in the mandibular retromolar area. Case report. Aust Dent J 44:135–136
Cheng J, Saku T, Okabe H, et al. (1992) Basement membranes in adenoid cystic carcinoma. An immunohistochemical study. Cancer 69:2631–2640
Chetty R (1998) HIV-associated lymphoepithelial cysts and lesions: morphological and immunohistochemical study of the lymphoid cells. Histopathology 33:222–229
Cheuk W, Miliauskas JR, Chan JKC (2004) Intraductal carcinoma of the oral cavity: a case report and a reappraisal of the concept of pure ductal carcinoma in situ in salivary duct carcinoma. [see comment]. Am J Surg Pathol 28:266–270
Chhieng DC, Paulino AF (2002) Cytology of myoepithelial carcinoma of the salivary gland. Cancer 96:32–36
Chilla R (1981) Sialadenosis of the salivary glands of the head. Studies on the physiology and pathophysiology of parotid secretion. Adv Otorhinolaryngol 26:1–38
Chilla R, Schroth R, Eysholdt U, et al. (1980) Adenoid cystic carcinoma of the head and neck. Controllable and uncontrollable factors in treatment and prognosis. ORL J Otorhinolaryngol Relat Spec 42:346–367
Chilla R, Witzemann V, Opaitz M, et al. (1981) Possible involvement of parotid beta-adrenergic receptors in the etiology of sialadenosis. Arch Otorhinolaryngol 230:113–120
Cho KJ, el-Naggar AK, Ordonez NG, et al. (1995) Epithelial-myoepithelial carcinoma of salivary glands. A clinicopathologic, DNA flow cytometric, and immunohistochemical study of Ki-67 and HER-2/neu oncogene. Am J Clin Pathol 103:432–437
Choi HR, Batsakis JG, Callender DL, et al. (2002) Molecular analysis of chromosome 16q regions in dermal analogue tumors of salivary glands: a genetic link to dermal cylindroma? Am J Surg Pathol 26:778–783
Chong GC, Beahrs OH, Woolner LB (1974) Surgical management of acinic cell carcinoma of the parotid gland. Surg Gynecol Obstet 138:65–68
Clark DB, Priddy RW, Swanson AE (1990) Oral inverted ductal papilloma. Oral Surg Oral Med Oral Pathol 69:487–490
Conley J, Dingman DL (1974) Adenoid cystic carcinoma in the head and neck (cylindroma). Arch Otolaryngol 100:81–90
Corio RL, Sciubba JJ, Brannon RB, et al. (1982) Epithelialmyoepithelial carcinoma of intercalated duct origin. A clinicopathologic and ultrastructural assessment of sixteen cases. Oral Surg Oral Med Oral Pathol 53:280–287
Cornog J, Gray S (1976) Surgical and clinical pathology of salivary gland tumors. Diseases of the Salivary Glands. Edited by Rankow R, Polayes I. Philadelphia, WB Saunders Co., pp 130–142
Cornog JL (1970) Surgical and clinical pathology of salivary gland tumors Diseases of Salivary Glands Edited by Rankow R, Polayes I. Philadelphia, WB Saunders Co., pp 92–142
Corridan M (1956) Glycogen-rich clear cell adenoma of the parotid. J Pathol Bacteriol 72:623–627
Crumpler C, Scharfenberg JC, Reed RJ (1976) Monomorphic adenomas of salivary glands. Trabecular-tubular, canalicular, and basaloid variants. Cancer 38:193–200
Curran AE, White DK, Damm DD, et al. (2001) Polymorphous low-grade adenocarcinoma versus pleomorphic adenoma of minor salivary glands: resolution of a diagnostic dilemma by immunohistochemical analysis with glial fibrillary acidic protein. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 91:194–199
da Cruz Perez DE, de Abreu Alves F, Nobuko Nishimoto I, et al. (2006) Prognostic factors in head and neck adenoid cystic carcinoma. Oral Oncol 42:139–146
Dagrada GP, Negri T, Tamborini E, et al. (2004) Expression of HER-2/neu gene and protein in salivary duct carcinomas of parotid gland as revealed by fluorescence in-situ hybridization and immunohistochemistry. [comment]. Histopathology 44:301–302
Daley TD, Gardner DG, Smout MS (1984) Canalicular adenoma: not a basal cell adenoma. Oral Surg Oral Med Oral Pathol 57:181–188
Dalforno S, Donna A (1967) [Sebaceous adenoma of the salivary gland]. Cancro 20:667–673
Daniels TE (1984) Labial salivary gland biopsy in Sjogren’s syndrome. Assessment as a diagnostic criterion in 362 suspected cases. Arthritis Rheum 27:147–156
Dardick I (1996) Salivary Gland Tumor Pathology. New York, Igaku-shoin, pp 235–239
Dardick I, Daley TD, van Nostrand AW (1986) Basal cell adenoma with myoepithelial cell-derived stroma: a new major salivary gland tumor entity. Head Neck Surg 8:257–267
Dardick I, Lytwyn A, Bourne AJ, et al. (1992) Trabecular and solid-cribriform types of basal cell adenoma. A morphologic study of two cases of an unusual variant of monomorphic adenoma. Oral Surg Oral Med Oral Pathol 73:75–83
Dardick I, Thomas MJ, van Nostrand AW (1989) Myoepithelioma — new concepts of histology and classification: a light and electron microscopic study. Ultrastruct Pathol 13:187–224
Darling MR, Schneider JW, Phillips VM (2002) Polymorphous low-grade adenocarcinoma and adenoid cystic carcinoma: a review and comparison of immunohistochemical markers. Oral Oncol 38:641–645
de Araujo VC, de Sousa SO, Carvalho YR, et al. (2000) Application of immunohistochemistry to the diagnosis of salivary gland tumors. Appl Immunohistochem Mol Morphol 8:195–202
De la Maza LM, Schwartz MM, Soto EA (1971) Sebaceous lymphadenoma of the parotid region. Arch Pathol 92:294–295
de Sousa SO, Schwarzschild M, de Araujo NS, et al. (2000) Basal cell adenocarcinoma of the palate with squamous metaplasia. J Clin Pathol 53:153–156
de Sousa SO, Sesso A, de Araujo NS, et al. (1995) Inverted ductal papilloma of minor salivary gland origin: morphological aspects and cytokeratin expression. Eur Arch Otorhinolaryngol 252:370–373
Delgado R, Klimstra D, Albores-Saavedra J (1996) Low grade salivary duct carcinoma. A distinctive variant with a low grade histology and a predominant intraductal growth pattern. Cancer 78:958–967
Delgado R, Vuitch F, Albores-Saavedra J (1992) High grade salivary duct carcinoma. Mod Pathol 5:71A
Deysine M, Mann BF Jr. (1969) Sebaceous lymphadenoma of the parotid gland: associated with a case of bilateral parotid gland tumors. Ann Surg 169:437–443
Di Palma S, Corletto V, Lavarino C, et al. (1999) Unilateral aneuploid dedifferentiated acinic cell carcinoma associated with bilateral-low grade diploid acinic cell carcinoma of the parotid gland. Virchows Arch 434:361–365
Di Palma S, Simpson RH, Skalova A, et al. (1999) Metaplastic (infarcted) Warthin’s tumour of the parotid gland: a possible consequence of fine needle aspiration biopsy. Histopathology 35:432–438
Di Palma S, Skalova A, Vanieek T, et al. (2005) Non-invasive (intracapsular) carcinoma ex pleomorphic adenoma: recognition of focal carcinoma by HER-2/neu and MIB1 immunohistochemistry. Histopathology 46:144–152
Dimery IW, Jones LA, Verjan RP, et al. (1987) Estrogen receptors in normal salivary gland and salivary gland carcinoma. Arch Otolaryngol Head Neck Surg 113:1082–1085
Dobson CM, Ellis HA (1987) Polycystic disease of the parotid glands: case report of a rare entity and review of the literature. Histopathology 11:953–961
Donath K (1976) [Sialadenosis of the parotid gland. Ultrastructural, clinical and experimental findings in disturbances of secretion (author’s transl)]. Veroff Pathol (103):1–122
Donath K, Seifert G (1972) [Ultrastructure and pathogenesis of myoepithelial sialadenitis. Occurrence of myoepithelial cells in the benign lymphoepithelial lesion (Sjogren’s syndrome)]. Virchows Arch A Pathol Anat 356:315–329
Donath K, Seifert G (1972) Zur Diagnose and Ultrastruktur des tubularen Speichelgangcarcinoms. Epithelial-myoepitheliales Schaltstruckcarcinom. Virchows Arch A Pathol Anat 356:16–31
Donath K, Seifert G (1975) Ultrastructural studies of the parotid glands in sialadenosis. Virchows Arch A Pathol Anat Histol 365:119–135
Donath K, Spillner M, Seifert G (1974) The influence of the autonomic nervous system on the ultrastructure of the parotid acinar cells. Experimental contribution to the neurohormonal sialadenosis. Virchows Arch A Pathol Anat Histol 364:15–33
Dreyer T, Battmann A, Silberzahn J, et al. (1993) Unusual differentiation of a combination tumor of the parotid gland. A case report. Pathol Res Pract 189:577–581; discussion 581–575
Edwards PC, Bhuiya T, Kelsch RD (2003) C-kit expression in the salivary gland neoplasms adenoid cystic carcinoma, polymorphous low-grade adenocarcinoma, and monomorphic adenoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 95:586–593
Edwards PC, Bhuiya T, Kelsch RD (2004) Assessment of p63 expression in the salivary gland neoplasms adenoid cystic carcinoma, polymorphous low-grade adenocarcinoma, and basal cell and canalicular adenomas. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 97:613–619
Eibling DE, Johnson JT, McCoy JP Jr., et al. (1991) Flow cytometric evaluation of adenoid cystic carcinoma: correlation with histologic subtype and survival. Am J Surg 162:367–372
el-Naggar AK, Batsakis JG, Luna MA, et al. (1990) DNA flow cytometry of acinic cell carcinomas of major salivary glands. J Laryngol Otol 104:410–416
el-Naggar AK, Lovell M, Callender DL, et al. (1999) Cytogenetic analysis of a primary salivary gland myoepithelioma. Cancer Genet Cytogenet 113:49–53
el-Naggar AK (2005) Adenoid cystic carcinomas in Pathology and Genetics Head and Neck Tumors. Edited by Barnes EL, Eveson JW, Reichart P, Sidransky D. Lyon, IARC Press, pp 221–222
Elliott JN, Oertel YC (1990) Lymphoepithelial cysts of the salivary glands. Histologic and cytologic features. Am J Clin Pathol 93:39–43
Ellis G, Auclair P (1996) Tumors of the Salivary Glands, Atlas of Tumor Pathology, third series, fascicle 17. Washington DC, Armed Forces Institute of Pathology, pp 296–369
Ellis G, Auclair P (1996) Tumors of the Salivary Glands, Atlas of Tumor Pathology, third series, fascicle 17. Washington DC, Armed Forces Institute of Pathology, pp 289–296
Ellis G, Simpson R (2005) Acinic cell carcinoma in Pathology and Genetics Head and Neck Tumours (edited by Barnes L, Eveson J, Reichart P, Sidransky D) WHO, Lyon. France, IARC Press, pp 216–218
Ellis GL (1998) Clear cell neoplasms in salivary glands: clearly a diagnostic challenge. Ann Diagn Pathol 2:61–78
Ellis GL, Auclair PL, Gnepp DR, et al. (1991) Other malignant neoplasms in. Surgical Pathology of the Salivary Glands. Philadelphia, WB Saunders, pp 455–488
Ellis GL, Auclair PL (1991) Acinic cell adenocarcinoma in Surgical Pathology of the Salivary Glands (Ellis GL, Auclair PL, Gnepp DR, editors). Philadelphia, WB Saunders Co., pp 299–317
Ellis GL, Auclair PL (1996) Acinic cell carcinoma in Tumors of the Salivary Glands, Atlas of Tumor Pathology, third series, fascicle 17. Washington DC, Armed Forces Institute of Pathology, pp 183–203
Ellis GL, Auclair PL (1996) Tumors of the Salivary Glands, Atlas of Tumor Pathology, third series, fascicle 17. Washington DC, Armed Forces Institute of Pathology, pp 1–26
Ellis GL, Auclair PL (1991) Ductal Papillomas. Surgical pathology of the salivary glands. Philadelphia, W.B. Saunders, pp 238–252
Ellis GL, Auclair PL (1996) Tumors of the salivary glands. Washington D.C., Armed Forces Institute of Pathology, pp 268–281
Ellis GL, Corio RL (1983) Acinic cell adenocarcinoma. A clinicopathologic analysis of 294 cases. Cancer 52:542–549
Ellis GL, Wiscovitch JG (1990) Basal cell adenocarcinomas of the major salivary glands. Oral Surg Oral Med Oral Pathol 69:461–469
Emanuel P, Wang B, Wu M, et al. (2005) p63 Immunohistochemistry in the distinction of adenoid cystic carcinoma from basaloid squamous cell carcinoma. Mod Pathol 18:645–650
Enamorado I, Lakhani R, Korkmaz H, et al. (2004) Correlation of histopathological variants, cellular DNA content, and clinical outcome in adenoid cystic carcinoma of the salivary glands. Otolaryngol Head Neck Surg 131:646–650
Eneroth CM (1970) Incidence and prognosis of salivary glands tumors at different sites. A study of parotid, submandibular and palatal tumors in 2632 patients. Acta Otolarynogol Suppl 263:174–178
Eneroth CM (1971) Salivary gland tumors in the parotid gland, submandibular gland, and the palate region. Cancer 27:1415–1418
Eneroth CM, Blanck C, Jakobsson PA (1968) Carcinoma in pleomorphic adenoma of the parotid gland. Acta Otolaryngol 66:477–492
Eneroth CM, Hjertman L, Moberger G, et al. (1972) Mucoepidermoid carcinomas of the salivary glands with special reference to the possible existence of a benign variety. Acta Otolaryngol 73:68–74
Eneroth CM, Zetterberg A (1974) Malignancy in pleomorphic adenoma. A clinical and microspectrophotometric study. Acta Otolaryngol 77:426–432
Enlund F, Nordkvist A, Sahlin P, et al. (2002) Expression of PLAG1 and HMGIC proteins and fusion transcripts in radiation-associated pleomorphic adenomas. Int J Oncol 20:713–716
Epker BN, Henny FA (1971) Intra-oral sebaceous gland adenoma. Cancer 27:987–1000
Erlandson RA, Tandler B (1972) Ultrastructure of acinic cell carcinoma of the parotid gland. Arch Pathol Lab Med 93:130–140
Evans HL, Batsakis JG (1984) Polymorphous low-grade adenocarcinoma of minor salivary glands. A study of 14 cases of a distinctive neoplasm. Cancer 53:935–942
Evans HL, Luna MA (2000) Polymorphous low-grade adenocarcinoma: a study of 40 cases with long-term follow up and an evaluation of the importance of papillary areas. Am J Surg Pathol 24:1319–1328
Evans R, Cruickshank A (1970) Epithelial Tumors of the Salivary Glands. Philadelphia, W.B. Saunders Co., pp 226–241
Eversole L (2001) Salivary gland pathology. Head and neck pathology: with clinical correlations. Edited by Fu Y, Wenig BM, Abemayor E, Wenig BL. Philadelphia, Churchill-Livingstone, pp 242–291
Eversole LR, Gnepp DR, Eversole GM (1991) Undifferentiated carcinoma in Surgical Pathology of the Salivary Glands, (Ellis GL, Auclair PL, Gnepp DR, editors) Philadelphia, WB Saunders Co., pp 422–440
Eveson JW, Auclair PL, Gnepp D, et al. (2005) Tumors of Salivary Glands in Pathology and Genetics Head and Neck Tumors. Edited by Barnes EL, Eveson JW, Reichart P, Sidransky D. Lyon, IARC Press, pp 212–215
Eveson JW, Cawson RA (1985) Salivary gland tumours. A review of 2410 cases with particular reference to histological types, site, age and sex distribution. J Pathol 146:51–58
Eveson JW, Cawson RA (1985) Tumours of the minor (oropharyngeal) salivary glands: a demographic study of 336 cases. J Oral Pathol 14:500–509
Eveson JW, Cawson RA (1989) Infarcted (infected) adenolymphomas. A clinicopathological study of 20 cases. Clin Otolaryngol 14:205–210
Eveson JW, Kusafuka K, Stenman G, et al. (2005) Pleomorphic adenoma. Pathology and Classification of Head and Neck Tumours. Edited by Barnes EL, Eveson JW, Reichart P, Sidransky D. Lyon, IARC
Ezsias A, Sugar AW, Milling MA, et al. (1994) Central mucoepidermoid carcinoma in a child. J Oral Maxillofac Surg 52:512–515
Fadare O, Hileeto D, Gruddin YL, et al. (2004) Sclerosing mucoepidermoid carcinoma of the parotid gland. Arch Pathol Lab Med 128:1046–1049
Faivre S, Raymond E, Casiraghi D, et al. (2005) Imatinib mesylate can induce objective response in progressing, highly expressing KIT adenoid cystic carcinoma of the salivary glands. J Clin Oncol 23:6271–6273
Fan CY, Melhem MF, Hosal AS, et al. (2001) Expression of androgen receptor, epidermal growth factor receptor, and transforming growth factor alpha in salivary duct carcinoma. Arch Otolaryngol Head Neck Surg 127:1075–1079
Fauci AS, Haynes BF, Katz P, et al. (1983) Wegener’s granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years. Ann Intern Med 98:76–85
Felix A, Rosa-Santos J, Mendonca ME, et al. (2002) Intracapsular carcinoma ex pleomorphic adenoma. Report of a case with unusual metastatic behaviour. Oral Oncol 38:107–110
Ferguson JW, Geary CP, MacAlister AD (1987) Sebaceous cell adenoma. Rare intra-oral occurrence of a tumour which is a frequent marker of Torre’s syndrome. Pathology 19:204–208
Ferreiro JA (1994) Immunohistochemical analysis of salivary gland canalicular adenoma. Oral Surg Oral Med Oral Pathol 78:761–765
Ferreiro JA (2005) Canalicular adenoma. Pathology and Classification of Head and Neck Tumours. Edited by Barnes EL, Eveson JW, Reichart P, Sidransky D. Lyon, IARC, pp 267
Ficarra G, Sapp JP, Christensen RE, et al. (1996) Dysgenetic polycystic disease of the parotid gland: report of case. J Oral Maxillofac Surg 54:1246–1249
Finn DG, Buchalter IH, Sarti E, et al. (1987) First branchial cleft cysts: clinical update. Laryngoscope 97:136–140
Firat P, Hosal S, Tutar E, et al. (2000) Sebaceous lymphadenoma of the parotid gland. J Otolaryngol 29:114–116
Fishleder A, Tubbs R, Hesse B, et al. (1987) Uniform detection of immunoglobulin-gene rearrangement in benign lymphoepithelial lesions. N Engl J Med 316:1118–1121
Fleming DA, Morrice I (1973) Sebaceous lymphadenoma of the parotid gland: a report of a case. J Pathol 110:259–261
Flynn MB, Maguire S, Martinez S, et al. (1999) Primary squamous cell carcinoma of the parotid gland: the importance of correct histological diagnosis. Ann Surg Oncol 6:768–770
Fonseca I, Soares J (1993) Epithelial-myoepithelial carcinoma of the salivary glands. A study of 22 cases. Virchows Arch A Pathol Anat Histopathol 422:389–396
Fonseca I, Soares J (1993) Proliferating cell nuclear antigen immunohistochemistry in epithelial-myoepithelial carcinoma of the salivary glands. Arch Pathol Lab Med 117:993–995
Foote FW Jr., Frazell EL (1953) Tumors of the major salivary glands. Cancer 6:1065–1133
Foschini MP, Gaiba A, Cocchi R, et al. (2005) p63 expression in salivary gland tumors: role of DeltaNp73L in neoplastic transformation. Int J Surg Pathol 13:329–335
Foss RD, Ellis GL, Auclair PL (1996) Salivary gland cystadenocarcinomas. A clinicopathologic study of 57 cases. Am J Surg Pathol 20:1440–1447
Fowler CB, Brannon RB (2000) Subacute necrotizing sialadenitis: report of 7 cases and a review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 89:600–609
Fowler MH, Fowler J, Ducatman B, et al. (2006) Malignant mixed tumors of the salivary gland: a study of loss of heterozygosity in tumor suppressor genes. Mod Pathol 19:350–355
Fox RI (2005) Sjogren’s syndrome. Lancet 366:321–331
Franzen G, Klausen OG, Grenko RT, et al. (1991) Adenoid cystic carcinoma: DNA as a prognostic indicator. Laryngoscope 101:669–673
Franzen G, Nordgard S, Boysen M, et al. (1995) DNA content in adenoid cystic carcinomas. Head Neck 17:49–55
Freedman PD, Lumerman H (1983) Lobular carcinoma of intraoral minor salivary gland origin. Report of twelve cases. Oral Surg Oral Med Oral Pathol 56:157–166
Freeman SB, Kennedy KS, Parker GS, et al. (1990) Metastasizing pleomorphic adenoma of the nasal septum. Arch Otolaryngol Head Neck Surg 116:1331–1333
Freier K, Flechtenmacher C, Walch A, et al. (2005) Differential KIT expression in histological subtypes of adenoid cystic carcinoma (ACC) of the salivary gland. Oral Oncol 41:934–939
Fujibayashi T, Itoh H (1981) Lymphoepithelial (so-called branchial) cyst within the parotid gland. Report of a case and review of the literature. Int J Oral Surg 10:283–292
Furuse C, Sousa SO, Nunes FD, et al. (2005) Myoepithelial cell markers in salivary gland neoplasms. Int J Surg Pathol 13:57–65
Furuse C, Tucci R, Machado de Sousa SO, et al. (2003) Comparative immunoprofile of polymorphous low-grade adenocarcinoma and canalicular adenoma. Ann Diagn Pathol 7:278–280
Gallo O, Bocciolini C (1997) Warthin’s tumour associated with autoimmune diseases and tobacco use. Acta Otolaryngol 117:623–627
Gandour-Edwards RF, Donald PJ, Vogt PJ, et al. (1994) Carcinosarcoma (malignant mixed tumor) of the parotid: report of a case with a pure rhabdomyosarcoma component. Head Neck 16:379–382
Garcia S, Martini F, Caces F, et al. (1998) [Polycystic disease of the salivary glands: report of an attack of the submaxillary glands]. Ann Pathol 18:58–60
Gardiner GW, Briant TD, Sheman L (1984) Inverted ductal papilloma of the parotid gland. J Otolaryngol 13:23–26
Gaughan RK, Olsen KD, Lewis JE (1992) Primary squamous cell carcinoma of the parotid gland. Arch Otolaryngol Head Neck Surg 118:798–801
George MK, Mansour P, Pahor AL (1991) Terminal parotid duct carcinoma. J Laryngol Otol 105:780–781
Gerughty RM, Scofield HH, Brown FM, et al. (1969) Malignant mixed tumors of salivary gland origin. Cancer 24:471–486
Geurts JM, Schoenmakers EF, Roijer E, et al. (1998) Identification of NFIB as recurrent translocation partner gene of HMGIC in pleomorphic adenomas. Oncogene 16:865–872
Geurts JM, Schoenmakers EF, Roijer E, et al. (1997) Expression of reciprocal hybrid transcripts of HMGIC and FHIT in a pleomorphic adenoma of the parotid gland. Cancer Res 57:13–17
Ghosh S, Panarese A, Bull PD, et al. (2003) Marginally excised parotid pleomorphic salivary adenomas: risk factors for recurrence and management. A 12.5-year mean follow-up study of histologically marginal excisions. Clin Otolaryngol 28:262–266
Gilcrease MZ, Nelson FS, Guzman-Paz M (1998) Tyrosinerich crystals associated with oncocytic salivary gland neoplasms. Arch Pathol Lab Med 122:644–649
Glisson B, Colevas AD, Haddad R, et al. (2004) HER2 expression in salivary gland carcinomas: dependence on histological subtype. Clin Cancer Res 10:944–946
Gnepp DR (1993) Malignant mixed tumors of the salivary glands: a review. Pathol Annu 28 Pt 1:279–328
Gnepp DR (2003) Sclerosing polycystic adenosis of the salivary gland: a lesion that may be associated with dysplasia and carcinoma in situ. Adv Anat Pathol 10:218–222
Gnepp DR (2005) Metastasizing pleomorphic adenoma. Pathology and Classification of Head and Neck Tumours. Edited by Barnes EL, Eveson JW, Reichart P, Sidransky D. Lyon, IARC, p 245
Gnepp DR, Brannon R (1984) Sebaceous neoplasms of salivary gland origin. Report of 21 cases. Cancer 53:2155–2170
Gnepp DR, Chen JC, Warren C (1988) Polymorphous low-grade adenocarcinoma of minor salivary gland. An immunohistochemical and clinicopathologic study. Am J Surg Pathol 12:461–468
Gnepp DR, Chen JC, Warren C (1988) Polymorphous low-grade adenocarcinoma of minor salivary gland. An immunohistochemical and clinicopathologic study. Am J Surg Pathol 12:461–468
Gnepp DR, Corio RL, Brannon RB (1986) Small cell carcinoma of the major salivary glands. Cancer 58:705–714
Gnepp DR, el-Mofty S (1997) Polymorphous low-grade adenocarcinoma: glial fibrillary acidic protein staining in the differential diagnosis with cellular mixed tumors. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 83:691–695
Gnepp DR, Ferlito A, Hyams V (1983) Primary anaplastic small cell (oat cell) carcinoma of the larynx. Review of the literature and report of 18 cases. Cancer 51:1731–1745
Gnepp DR, Wang LJ, Brandwein-Gensler M, et al. (2006) Sclerosing polycystic adenosis of the salivary gland: a report of 16 cases. Am J Surg Pathol 30:154–164
Goldfarb D, Mikaelian D, Keane WM (1994) Mucoepidermoid carcinoma of the mandible. Am J Otolaryngol 15:54–57
Goldman RL, Klein HZ (1972) Glycogen-rich adenoma of the parotid gland. An uncommon benign clear-cell tumor resembling certain clear-cell carcinomas of salivary origin. Cancer 30:749–754
Gomes AP, Sobral AP, Loducca SV, et al. (2004) Sialadenoma papilliferum: immunohistochemical study. Int J Oral Maxillofac Surg 33:621–624
Goode R, El-Nagger A (2005) Mucoepidermoid carcinoma. Pathology and Genetics Head and Neck Tumors. Edited by Barnes L, Eveson J, Reichart P, Sidransky D. Lyon, IARC Press, pp 219–220
Goode RK, Auclair PL, Ellis GL (1998) Mucoepidermoid carcinoma of the major salivary glands: clinical and histopathologic analysis of 234 cases with evaluation of grading criteria. Cancer 82:1217–1224
Goodisson DW, Burr RG, Creedon AJ, et al. (1999) A case of metastasizing pleomorphic adenoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 87:341–345
Gotte K, Riedel F, Coy JF, et al. (2000) Salivary gland carcinosarcoma: immunohistochemical, molecular genetic and electron microscopic findings. Oral Oncol 36:360–364
Gottesman RI, Som PM, Mester J, et al. (1996) Observations on two cases of apparent submandibular gland cysts in HIV positive patients: MR and CT findings. J Comput Assist Tomogr 20:444–447
Grage TB, Lober PH, Arhelger SW (1961) Acinic cell carcinoma of the parotid gland. Am J Surg 102:765–768
Greiner TC, Robinson RA, Maves MD (1989) Adenoid cystic carcinoma. A clinicopathologic study with flow cytometric analysis. Am J Clin Pathol 92:711–720
Gross M, Maly B, Goldfarb A, et al. (2004) Basal cell adenocarcinoma in a buccal minor salivary gland. Acta Otolaryngolog (Stockh) 124:213–216
Grotz KA, Wustenberg P, Kohnen R, et al. (2001) Prophylaxis of radiogenic sialadenitis and mucositis by coumarin/troxerutine in patients with head and neck cancer — a prospective, randomized, placebo-controlled, double-blind study. Br J Oral Maxillofac Surg 39:34–39
Gupta S, Sodhani P (1998) Sialadenosis of parotid gland: a cytomorphologic and morphometric study of four cases. Anal Quant Cytol Histol 20:225–228
Gurney TA, Eisele DW, Weinberg V, et al. (2005) Adenoid cystic carcinoma of the major salivary glands treated with surgery and radiation. Laryngoscope 115:1278–1282
Gustafsson H, Carlsoo B (1985) Multiple acinic cell carcinoma. Some histological and ultrastructural features of a case. J Laryngol Otol 99:1183–1193
Gustafsson H, Dahlqvist A, Anniko M, et al. (1987) Mucoepidermoid carcinoma in a minor salivary gland in childhood. J Laryngol Otol 101:1320–1323
Haberland-Carrodeguas C, Fornatora ML, Reich RF, et al. (2003) Detection of human papillomavirus DNA in oral inverted ductal papillomas. J Clin Pathol 56:910–913
Haines K, Murad T (1989) Infiltrating salivary duct carcinoma of the parotid. Lab Invest 60:36A
Hamed G, Shmookler BM, Ellis GL, et al. (1994) Oncocytic mucoepidermoid carcinoma of the parotid gland. Arch Pathol Lab Med 118:313–314
Hamper K, Brugmann M, Koppermann R, et al. (1989) Epithelial-myoepithelial duct carcinoma of salivary glands: a follow-up and cytophotometric study of 21 cases. J Oral Pathol Med 18:299–304
Hamper K, Lazar F, Dietel M, et al. (1990) Prognostic factors for adenoid cystic carcinoma of the head and neck: a retrospective evaluation of 96 cases. J Oral Pathol Med 19:101–107
Handra-Luca A, Lamas G, Bertrand JC, et al. (2005) MUC1, MUC2, MUC4, and MUC5AC expression in salivary gland mucoepidermoid carcinoma: diagnostic and prognostic implications. Am J Surg Pathol 29:881–889
Hansen A, Lipsky PE, Dorner T (2005) Immunopathogenesis of primary Sjogren’s syndrome: implications for disease management and therapy. Curr Opin Rheumatol 17:558–565
Hanson TA (1975) Acinic cell carcinoma of the parotid salivary gland presenting as a cyst. Report of two cases. Cancer 36:570–575
Hara H, Oyama T, Omori K, et al. (1999) Fine needle aspiration cytology of an intraductal papilloma originating in a sublingual gland. A case report. Acta Cytol 43:457–463
Hayashi Y, Aoki N (1983) Undifferentiated carcinoma of the parotid gland with bizarre giant cells. Clinicopathologic report with ultrastructural study. Acta Pathol Jpn 33:169–176
Hayashi Y, Nagamine S, Yanagawa T, et al. (1987) Small cell undifferentiated carcinoma of the minor salivary gland containing exocrine, neuroendocrine, and squamous cells. Cancer 60:1583–1588
Hayes MM, Cameron RD, Jones EA (1993) Sebaceous variant of mucoepidermoid carcinoma of the salivary gland. A case report with cytohistologic correlation. Acta Cytol 37:237–241
Hegarty DJ, Hopper C, Speight PM (1994) Inverted ductal papilloma of minor salivary glands. J Oral Pathol Med 23:334–336
Hellquist HB, Sundelin K, Di Bacco A, et al. (1997) Tumour growth fraction and apoptosis in salivary gland acinic cell carcinomas. Prognostic implications of Ki-67 and bcl-2 expression and of in situ end labelling (TUNEL). J Pathol 181:323–329
Henley J, Summerlin DJ, Potter D, et al. (2005) Intraoral mucin-rich salivary duct carcinoma.[comment]. Histopathology 47:436–437
Henley JD, Geary WA, Jackson CL, et al. (1997) Dedifferentiated acinic cell carcinoma of the parotid gland: a distinct rarely described entity. Hum Pathol 28:869–873
Henriksson G, Westrin KM, Carlsoo B, et al. (1998) Recurrent primary pleomorphic adenomas of salivary gland origin: intrasurgical rupture, histopathologic features, and pseudopodia. Cancer 82:617–620
Hiatt JL, Sank JJ (1991) Embryology and anatomy of salivary glands. Surgical Pathology of the Salivary Glands. Edited by Ellis GL A P, Gnepp DR. Philadelphia WB Saunders Co., pp 2–9
Hickman RE, Cawson RA, Duffy SW (1984) The prognosis of specific types of salivary gland tumors. Cancer 54:1620–1624
Honda K, Kashima K, Daa T, et al. (2000) Clonal analysis of the epithelial component of Warthin’s tumor. Hum Pathol 31:1377–1380
Honda T, Yamamoto Y, Isago T, et al. (2005) Giant pleomorphic adenoma of the parotid gland with malignant transformation. Ann Plast Surg 55:524–527
Hoorweg JJ, Hilgers FJ, Keus RB, et al. (1998) Metastasizing pleomorphic adenoma: a report of three cases. Eur J Surg Oncol 24:452–455
Hosal AS, Fan C, Barnes L, et al. (2003) Salivary duct carcinoma. Otolaryngology — Head Neck Surg 129:720–725
Hotte SJ, Winquist EW, Lamont E, et al. (2005) Imatinib mesylate in patients with adenoid cystic cancers of the salivary glands expressing c-kit: a Princess Margaret Hospital phase II consortium study. J Clin Oncol 23:585–590
Howard DJ, Lund VJ (1985) Reflections on the management of adenoid cystic carcinoma of the nasal cavity and paranasal sinuses. Otolaryngol Head Neck Surg 93:338–341
Hrynchak M, White V, Berean K, et al. (1994) Cytogenetic findings in seven lacrimal gland neoplasms. Cancer Genet Cytogenet 75:133–138
Huang JW, Ming Z, Shrestha P, et al. (1996) Immunohistochemical evaluation of the Ca(2+)-binding S-100 proteins S-100A1, S-100A2, S-100A4, S-100A6 and S-100B in salivary gland tumors. J Oral Pathol Med 25:547–555
Hughes KV 3rd, Olsen KD, McCaffrey TV (1995) Parapharyngeal space neoplasms. Head Neck 17:124–130
Hui KK, Luna MA, Batsakis JG, et al. (1990) Undifferentiated carcinomas of the major salivary glands. Oral Surg Oral Med Oral Pathol 69:76–83
Hungermann D, Roeser K, Buerger H, et al. (2002) Relative paucity of gross genetic alterations in myoepitheliomas and myoepithelial carcinomas of salivary glands. J Pathol 198:487–494
Hyjek E, Smith WJ, Isaacson PG (1988) Primary B-cell lymphoma of salivary glands and its relationship to myoepithelial sialadenitis. Hum Pathol 19:766–776
Ibrahim NB, Briggs JC, Corbishley CM (1984) Extrapulmonary oat cell carcinoma. Cancer 54:1645–1661
Ibrahim R, Bird DJ, Sieler MW (1991) Malignant myoepithelioma of the larynx with massive metastatic spread to the liver: an ultrastructural and immunocytochemical study. Ultrastruct Pathol 15:69–76
Ide F, Mishima K, Saito I (2003) Sarcomatoid salivary duct carcinoma of the oral cavity. Virchows Archiv 443:686–689
Ide F, Obara K, Enatsu K, et al. (2005) Sclerosing mucoepidermoid carcinoma of the oral cavity. J Oral Pathol Med 34:187–189
Iezzi G, Rubini C, Fioroni M, et al. (2002) Sebaceous adenoma of the cheek. Oral Oncol 38:111–113
Ihrler S, Steger W, Riederer A, et al. (1996) [HIV-associated cysts of the parotid glands. An histomorphologic and magnetic resonance tomography study of formal pathogenesis]. Laryngorhinootologie 75:671–676
Ihrler S, Zietz C, Riederer A, et al. (1996) HIV-related parotid lymphoepithelial cysts. Immunohistochemistry and 3-D reconstruction of surgical and autopsy material with special reference to formal pathogenesis. Virchows Arch 429:139–147
Ihrler S, Zietz C, Sendelhofert A, et al. (1999) Lymphoepithelial duct lesions in Sjogren-type sialadenitis. Virchows Arch 434:315–323
Imamura Y, Morishita T, Kawakami M, et al. (2004) Sclerosing polycystic adenosis of the left parotid gland: report of a case with fine needle aspiration cytology. Acta Cytol 48:569–573
Imbery TA, Edwards PA (1996) Necrotizing sialometaplasia: literature review and case reports. J Am Dent Assoc 127:1087–1092
Inoue Y, Nomura J, Hashimoto M, et al. (2001) Epithelialmyoepithelial carcinoma of the palate: a case report. J Oral Maxillofac Surg 59:1502–1505
Izutsu T, Kumamoto H, Kimizuka S, et al. (2003) Sebaceous adenoma in the retromolar region: report of a case with a review of the English literature. Int J Oral Maxillofac Surg 32:423–426
Jaehne M, Roeser K, Jaekel T, et al. (2005) Clinical and immunohistologic typing of salivary duct carcinoma: a report of 50 cases. Cancer 103:2526–2533
Jahan-Parwar B, Huberman RM, Donovan DT, et al. (1999) Oncocytic mucoepidermoid carcinoma of the salivary glands. Am J Surg Pathol 23:523–529
James GK, Pudek M, Berean KW, et al. (1996) Salivary duct carcinoma secreting prostate-specific antigen. Am J Clin Pathol 106:242–247
Jayakrishnan A, Elmalah I, Hussain K, et al. (2003) Basal cell adenocarcinoma in minor salivary glands. Histopathology 42:610–614
Jeng YM, Lin CY, Hsu HC (2000) Expression of the c-kit protein is associated with certain subtypes of salivary gland carcinoma. Cancer Lett 154:107–111
Jervis PN, Lee JA, Bull PD (2001) Management of nontuberculous mycobacterial peri-sialadenitis in children: the Sheffield otolaryngology experience. Clin Otolaryngol 26:243–248
Johnston N, Rose D, Lutterloch M (2005) Cystadenocarcinoma of salivary gland presenting as a cystic lesion in the mandible. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 101:201–204
Jurgens PE (2004) Inverted ductal papilloma of the lower lip: a case report. J Oral Maxillofac Surg 62:1158–1161
Kaminagakura E, Andrade CR, Rangel AL, et al. (2003) Sebaceous adenoma of oral cavity: report of case and comparative proliferation study with sebaceous gland hyperplasia and Fordyce’s granules. Oral Dis 9:323–327
Kamisawa T, Nakajima H, Egawa N, et al. (2005) IgG4-Related Sclerosing Disease Incorporating Sclerosing Pancreatitis, Cholangitis, Sialadenitis and Retroperitoneal Fibrosis with Lymphadenopathy. Pancreatology 6:132–137
Kanazawa H, Furuya T, Murano A, et al. (2000) Oncocytoma of an intraoral minor salivary gland: report of a case and review of literature. J Oral Maxillofac Surg 58:894–897
Kas K, Voz ML, Roijer E, et al. (1997) Promoter swapping between the genes for a novel zinc finger protein and betacatenin in pleiomorphic adenomas with t(3;8)(p21;q12) translocations. Nat Genet 15:170–174
Kasaboglu O, Er N, Tumer C, et al. (2004) Micromorphology of sialoliths in submandibular salivary gland: a scanning electron microscope and X-ray diffraction analysis. J Oral Maxillofac Surg 62:1253–1258
Kemp BL, Batsakis JG, el-Naggar AK, et al. (1995) Terminal duct adenocarcinomas of the parotid gland. J Laryngol Otol 109:466–468
Khullar SM, Best PV (1992) Adenomatosis of minor salivary glands. Report of a case. Oral Surg Oral Med Oral Pathol 74:783–787
Kici S, Peytral C (2001) [Giant pleomorphic adenoma of the parotid gland: a case report and review of the literature]. Ann Otolaryngol Chir Cervicofac 118:330–332
King OH Jr. (1967) Carcinosarcoma of accessory salivary gland. First report of a case. Oral Surg Oral Med Oral Pathol 23:651–659
Kirklin JW, Mc DJ, Harrington SW, et al. (1951) Parotid tumors; histopathology, clinical behavior, and end results. Surg Gynecol Obstet 92:721–733
Kitagawa S, Zen Y, Harada K, et al. (2005) Abundant IgG4-positive plasma cell infiltration characterizes chronic sclerosing sialadenitis (Kuttner’s tumor). Am J Surg Pathol 29:783–791
Kjorell U, Ostberg Y (1984) Distribution of intermediate filaments and actin microfilaments in parotid autoimmune sialoadenitis of Sjogren syndrome. Histopathology 8:991–1011
Kleinsasser O, Klein HJ, Hubner G (1968) Salivary duct carcinoma. A group of salivary gland tumors analogous to mammary duct carcinoma. Arch Klin Exp Ohren-Nasen-Kehlkopfheilk 192:100–105
Klima M, Wolfe K, Johnson PE (1978) Basal cell tumors of the parotid gland. Arch Otolaryngol 104:111–116
Klumpp TR, Mohr RM, Silverman CL, et al. (1995) Malignant myoepithelioma of the parotid gland: case report and review of the literature. J Laryngol Otol 109:995–998
Knowles DM, Athan E, Ubriaco A, et al. (1989) Extranodal noncutaneous lymphoid hyperplasias represent a continuous spectrum of B-cell neoplasia: demonstration by molecular genetic analysis. Blood 73:1635–1645
Koka VN, Tiwari RM, van der Waal I, et al. (1989) Adenoid cystic carcinoma of the salivary glands: clinicopathological survey of 51 patients. J Laryngol Otol 103:675–679
Kokemueller H, Brueggemann N, Swennen G, et al. (2005) Mucoepidermoid carcinoma of the salivary glands-clinical review of 42 cases. Oral Oncol 41:3–10
Koss LG, Spiro RH, Hajdu S (1972) Small cell (oat cell) carcinoma of minor salivary gland origin. Cancer 30:737–741
Kotwall CA (1992) Smoking as an etiologic factor in the development of Warthin’s tumor of the parotid gland. Am J Surg 164:646–647
Koutlas IG, Jessurun J, Iamaroon A (1994) Immunohistochemical evaluation and in situ hybridization in a case of oral inverted ductal papilloma. J Oral Maxillofac Surg 52:503–506
Krolls SO, Trodahl JN, Boyers RC (1972) Salivary gland lesions in children. A survey of 430 cases. Cancer 30:459–469
Kunze P (1979) [Sebaceous lymphadenoma of the parotid gland (author’s transl)]. Zentralbl Allg Pathol 123:210–213
Kwon GY, Kim EJ, Go JH (2002) Lymphadenoma arising in the parotid gland: a case report. Yonsei Med J 43:536–538
Kwon MY, Gu M (2001) True malignant mixed tumor (carcinosarcoma) of parotid gland with unusual mesenchymal component: a case report and review of the literature. Arch Pathol Lab Med 125:812–815
Labouyrie E, Merlio JP, Beylot-Barry M, et al. (1993) Human immunodeficiency virus type 1 replication within cystic lymphoepithelial lesion of the salivary gland. Am J Clin Pathol 100:41–46
Larsson LG, Donner LR (1999) Large cell neuroendocrine carcinoma of the parotid gland: fine needle aspiration, and light microscopic and ultrastructural study. Acta Cytol 43:534–536
Leafstedt SW, Gaeta JF, Sako K, et al. (1971) Adenoid cystic carcinoma of major and minor salivary glands. Am J Surg 122:756–762
Lebsack JP, Marrogi AJ, Martin SA (1990) Central mucoepidermoid carcinoma of the jaw with distant metastasis: a case report and review of the literature. J Oral Maxillofac Surg 48:518–522
Lee DJ, Smith RR, Spaziani JT, et al. (1985) Adenoid cystic carcinoma of the nasopharynx. Case reports and literature review. Ann Otol Rhinol Laryngol 94:269–272
Lee IK, Liu JW (2005) Tuberculous parotitis: case report and literature review. Ann Otol Rhinol Laryngol 114:547–551
Lee JH, Lee JH, Kim A, et al. (2005) Unique expression of MUC3, MUC5AC and cytokeratins in salivary gland carcinomas. Pathol Int 55:386–390
Lee KC, Chan JK, Chong YW (1992) Ossifying pleomorphic adenoma of the maxillary antrum. J Laryngol Otol 106:50–52
Lee S, Kim GE, Park CS, et al. (2001) Primary squamous cell carcinoma of the parotid gland. Am J Otolaryngol 22:400–406
Leverstein H, van der Wal JE, Tiwari RM, et al. (1997) Surgical management of 246 previously untreated pleomorphic adenomas of the parotid gland. Br J Surg 84:399–403
Levin JM, Robinson DW, Lin F (1975) Acinic cell carcinoma. Arch Surg 110:64–68
Lewis JE, McKinney BC, Weiland LH, et al. (1996) Salivary duct carcinoma. Clinicopathologic and immunohistochemical review of 26 cases. Cancer 77:223–230
Lewis JE, Olsen KD (2005) Tumors of Salivary Glands. Pathology and Genetics Head and Neck Tumors. Edited by Barnes EL, Eveson J, Reichart P, Sidransky D. Lyon, IARC, pp 245–246
Lewis JE, Olsen KD, Sebo TJ (2001) Carcinoma ex pleomorphic adenoma: pathologic analysis of 73 cases. Hum Pathol 32:596–604
Lewis JE, Olsen KD, Weiland LH (1991) Acinic cell carcinoma. Clinicopathologic review. Cancer 67:172–179
Lewis PD, Baxter P, Paul Griffiths A, et al. (2000) Detection of damage to the mitochondrial genome in the oncocytic cells of Warthin’s tumour. J Pathol 191:274–281
Lewis PD, Fradley SR, Griffiths AP, et al. (2002) Mitochondrial DNA mutations in the parotid gland of cigarette smokers and non-smokers. Mutat Res 518:47–54
Li S, Baloch ZW, Tomaszewski JE, et al. (2000) Worrisome histologic alterations following fine-needle aspiration of benign parotid lesions. Arch Pathol Lab Med 124:87–91
Li S, Baloch ZW, Tomaszewski JE, et al. (2000) Worrisome histologic alterations following fine-needle aspiration of benign parotid lesions. Arch Pathol Lab Med 124:87–91
Lin Y, Wu H, Tzeng J (2005) Small-cell undifferentiated carcinoma of the submandibular gland: An extremely rare extrapulmonary site. Am J Otolaryngol 26:60–63
Lins JE, Gnepp DR (1986) Myoepithelioma of the palate in a child. Int J Pediatr Otorhinolaryngol 11:5–13
Lipani C, Woytash JJ, Greene GW Jr. (1983) Sebaceous adenoma of the oral cavity. J Oral Maxillofac Surg 41:56–60
Littman CD, Alguacil-Garcia A (1987) Clear cell carcinoma arising in pleomorphic adenoma of the salivary gland. Am J Clin Pathol 88:239–243
LiVolsi VA, Perzin KH (1977) Malignant mixed tumors arising in salivary glands. I. Carcinomas arising in benign mixed tumors: a clinicopathologic study. Cancer 39:2209–2230
Lombardi T, Samson J, Kuffer R (2003) Subacute necrotizing sialadenitis: a form of necrotizing sialometaplasia? Arch Otolaryngol Head Neck Surg 129:972–975
Love GL, Sarma DP (1986) Spindle cell mucoepidermoid carcinoma of submandibular gland. J Surg Oncol 31:66–68
Loy TS, McLaughlin R, Odom LF, et al. (1989) Mucoepidermoid carcinoma of the parotid as a second malignant neoplasm in children. Cancer 64:2174–2177
Lucarini JW, Sciubba JJ, Khettry U, et al. (1994) Terminal duct carcinoma. Recognition of a low-grade salivary adenocarcinoma. [see comment]. Arch Otolaryngol Head Neck Surg 120:1010–1015
Luna MA, Batsakis JG, Tortoledo ME, et al. (1989) Carcinomas ex monomorphic adenoma of salivary glands. J Laryngol Otol 103:756–759
Luna MA, el-Naggar A, Batsakis JG, et al. (1990) Flow cytometric DNA content of adenoid cystic carcinoma of submandibular gland. Correlation of histologic features and prognosis. Arch Otolaryngol Head Neck Surg 116:1291–1296
Luna MA, Ordonez NG, Mackay B, et al. (1985) Salivary epithelial-myoepithelial carcinomas of intercalated ducts: a clinical, electron microscopic, and immunocytochemical study. Oral Surg Oral Med Oral Pathol 59:482–490
Luna MA, Tortoledo ME, Allen M (1987) Salivary dermal analogue tumors arising in lymph nodes. Cancer 59:1165–1169
Ma J, Chan JK, Chow CW, et al. (2002) Lymphadenoma: a report of three cases of an uncommon salivary gland neoplasm. Histopathology 41:342–350
Maisel RH, Johnston WH, Anderson HA, et al. (1977) Necrotizing sialometaplasia involving the nasal cavity. Laryngoscope 87:429–434
Mandel L, Carrao V (2005) Bilateral parotid diffuse hyperplastic oncocytosis: case report. J Oral Maxillofac Surg 63:560–562
Mandel L, Kim D, Uy C (1998) Parotid gland swelling in HIV diffuse infiltrative CD8 lymphocytosis syndrome. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 85:565–568
Mandel L, Surattanont F (2002) Bilateral parotid swelling: a review. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 93:221–237
Marciani RD, Trodahl JN, Dauchess VG, et al. (1976) Squamous cell carcinoma of the submandibular gland. J Oral Surg 34:646–650
Mariappan MR, Fadare O, Jain D (2004) Sebaceous differentiation in salivary glands. Arch Pathol Lab Med 128:245–246
Marie B, Labouyrie E, Scheid P, et al. (1997) Human immunodeficiency virus type 1 in an unusual cystic lymphoepithelial lesion of the lung. Histopathology 31:83–86
Marioni G, Marino F, Stramare R, et al. (2003) Benign metastasizing pleomorphic adenoma of the parotid gland: a clinicopathologic puzzle. Head Neck 25:1071–1076
Mark J, Dahlenfors R, Wedell B (1997) Impact of the in vitro technique used on the cytogenetic patterns in pleomorphic adenomas. Cancer Genet Cytogenet 95:9–15
Marks MW, Ryan RF, Litwin MS, et al. (1987) Squamous cell carcinoma of the parotid gland. Plast Reconstr Surg 79:550–554
Marmary Y, Gomori JM, Nitzan DW (1990) Lymphoepithelial parotid cysts as presenting symptom of immunodeficiency virus infection: clinical, sialographic, and magnetic resonance imaging findings. J Oral Maxillofac Surg 48:981–984
Martinez-Madrigal F, Micheau C (1989) Histology of the major salivary glands. Am J Surg Pathol 13:879–899
Martins C, Fonseca I, Roque L, et al. (1997) Cytogenetic characterisation of Warthin’s tumour. Oral Oncol 33:344–347
Matsuba HM, Simpson JR, Mauney M, et al. (1986) Adenoid cystic salivary gland carcinoma: a clinicopathologic correlation. Head Neck Surg 8:200–204
McAdams RM, Mair EA, Rajnik M (2005) Neonatal suppurative submandibular sialadenitis: case report and literature review. Int J Pediatr Otorhinolaryngol 69:993–997
McCluggage G, Sloan J, Cameron S, et al. (1995) Basal cell adenocarcinoma of the submandibular gland. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 79:342–350
McFerran DJ, Ingrams DR, Gallimore AP, et al. (1995) Polycystic disease of salivary glands. J Laryngol Otol 109:165–167
McGavran MH, Bauer WC, Ackerman LV (1960) Sebaceous lymphadenoma of the parotid salivary gland. Cancer 13:1185–1187
McKinney B, Lewis J, Weiland L, et al. (1994) Salivary duct carcinoma. Clinicopathologic and immunohistochemical review of 26 cases. Lab Invest 70:100A
McQuone SJ (1999) Acute viral and bacterial infections of the salivary glands. Otolaryngol Clin North Am 32:793–811
Mehta RP, Faquin WC, Deschler DG (2004) Pathology quiz case 1. Acinic cell carcinoma of the parotid gland with ductal extension. Arch Otolaryngol Head Neck Surg 130:790, 792–793
Mentzel T (2004) [Skin adnexal and salivary gland neoplasms. Similarities and differences of selected patients]. Pathologe 25:79–88
Merchant WJ, Cook MG, Eveson JW (1996) Polymorphous low-grade adenocarcinoma of parotid gland. Br J Oral Maxillofac Surg 34:328–330
Merwin WH Jr., Barnes L, Myers EN (1985) Unilocular cystic sebaceous lymphadenoma of the parotid gland. Arch Otolaryngol 111:273–275
Michal M, Skalova A, Simpson RH, et al. (1997) Well-differentiated acinic cell carcinoma of salivary glands associated with lymphoid stroma. Hum Pathol 28:595–600
Michal M, Skalova A, Simpson RH, et al. (1996) Clear cell malignant myoepithelioma of the salivary glands. Histopathology 28:309–315
Miettinen M, Lasota J (2005) KIT (CD117): a review on expression in normal and neoplastic tissues, and mutations and their clinicopathologic correlation. Appl Immunohistochem Mol Morphol 13:205–220
Miglianico L, Eschwege F, Marandas P, et al. (1987) Cervico-facial adenoid cystic carcinoma: study of 102 cases. Influence of radiation therapy. Int J Radiat Oncol Biol Phys 13:673–678
Mignogna MD, Fedele S, Lo Russo L (2004) Anorexia/bulimia-related sialadenosis of palatal minor salivary glands. J Oral Pathol Med 33:441–442
Miki H, Masuda E, Ohata S, et al. (1999) Late recurrence of acinic cell carcinoma of the parotid gland. J Med Invest 46:213–216
Milford CA, Mugliston TA, O’Flynn P, et al. (1989) Carcinoma arising in a pleomorphic adenoma of the epiglottis. J Laryngol Otol 103:324–327
Miliauskas JR (1991) Polymorphous low-grade (terminal duct) adenocarcinoma of the parotid gland. Histopathology 19:555–557
Mills SE, Garland TA, Allen MS Jr. (1984) Low-grade papillary adenocarcinoma of palatal salivary gland origin. Am J Surg Pathol 8:367–374
Mino M, Pilch BZ, Faquin WC (2003) Expression of KIT (CD117) in neoplasms of the head and neck: an ancillary marker for adenoid cystic carcinoma. Mod Pathol 16:1224–1231
Mitchell DA, Eveson JW, Ord RA (1989) Polymorphous low-grade adenocarcinoma of minor salivary glands — a report of three cases. Br J Oral Maxillofac Surg 27:494–500
Moberger JG, Eneroth CM (1968) Malignant mixed tumors of the major salivary glands. Special reference to the histologic structure in metastases. Cancer 21:1198–1211
Mohamed AH (1976) Ultrastructure of glycogen-rich clear cell carcinoma of the palate. J Oral Pathol 5:103–121
Mohamed AH, Cherrick HM (1975) Glycogen-rich adenocarcinoma of minor salivary glands. A light and electron microscopic study. Cancer 36:1057–1066
Mohammed BS, Liu Z, Tang W, et al. (2006) BCL-2, Ki67 and P53 expression in oral necrotizing sialometaplasia and squamous cell carcinoma. Mod Pathol 19:105A
Molina CP, Chaljub G, Campbell GA (2003) Pathologic quiz case: a 37-year-old man with spinal cord compression. Arch Pathol Lab Med 127:887–889
Monk JS Jr., Church JS (1992) Warthin’s tumor. A high incidence and no sex predominance in central Pennsylvania. Arch Otolaryngol Head Neck Surg 118:477–478
Moore JG, Bocklage T (1998) Fine-needle aspiration biopsy of large-cell undifferentiated carcinoma of the salivary glands: presentation of two cases, literature review, and differential cytodiagnosis of high-grade salivary gland malignancies. Diagn Cytopathol 19:44–50
Mostofi R, Wood RS, Christison W, et al. (1992) Low-grade papillary adenocarcinoma of minor salivary glands. Case report and literature review. Oral Surg Oral Med Oral Pathol 73:591–595
Muller S, Barnes L (1996) Basal cell adenocarcinoma of the salivary glands. Report of seven cases and review of the literature. Cancer 78:2471–2477
Muller S, Barnes L, Goodurn WJ Jr. (1997) Sclerosing mucoepidermoid carcinoma of the parotid. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 83:685–690
Murrah VA, Batsakis JG (1994) Salivary duct carcinoma. Ann Otol Rhinol Laryngol 103:244–247
Myerowitz RL, Barnes EL, Myers E (1978) Small cell anaplastic (oat cell) carcinoma of the larynx: report of a case and review of the literature. Laryngoscope 88:1697–1702
Nadiminti H, Thomas GR, Regalado J (2004) Pathology quiz case 1. Small cell carcinoma (SmCC) of the parotid gland. Arch Otolaryngol Head Neck Surg 130:474–477
Nagao K, Matsuzaki O, Saiga H, et al. (1983) A histopathologic study of benign and malignant lymphoepithelial lesions of the parotid gland. Cancer 52:1044–1052
Nagao K, Matsuzaki O, Saiga H, et al. (1982) Histopathologic studies of basal cell adenoma of the parotid gland. Cancer 50:736–745
Nagao K, Matsuzaki O, Saiga H, et al. (1982) Histopathologic studies of undifferentiated carcinoma of the parotid gland. Cancer 50:1572–1579
Nagao T, Gaffey TA, Kay PA, et al. (2003) Dedifferentiation in low-grade mucoepidermoid carcinoma of the parotid gland. Hum Pathol 34:1068–1072
Nagao T, Gaffey TA, Olsen KD, et al. (2004) Small cell carcinoma of the major salivary glands: clinicopathologic study with emphasis on cytokeratin 20 immunoreactivity and clinical outcome. Am J Surg Pathol 28:762–770
Nagao T, Gaffey TA, Serizawa H, et al. (2004) Sarcomatoid variant of salivary duct carcinoma: clinicopathologic and immunohistochemical study of eight cases with review of the literature. Am J Clin Pathol 122:222–231
Nagao T, Gaffey TA, Visscher DW, et al. (2004) Invasive micropapillary salivary duct carcinoma: a distinct histologic variant with biologic significance. Am J Surg Pathol 28:319–326
Nagao T, Serizawa H, Iwaya K, et al. (2002) Keratocystoma of the parotid gland: a report of two cases of an unusual pathologic entity. Mod Pathol 15(9):1005–1010.
Nagao T, Sugano I, Ishida Y, et al. (1998) Basal cell adenocarcinoma of the salivary glands: comparison with basal cell adenoma through assessment of cell proliferation, apoptosis, and expression of p53 and bcl-2. Cancer 82:439–447
Nagao T, Sugano I, Ishida Y, et al. (1998) Salivary gland malignant myoepithelioma: a clinicopathologic and immunohistochemical study of ten cases. Cancer 83:1292–1299
Nagao T, Sugano I, Ishida Y, et al. (2000) Primary large-cell neuroendocrine carcinoma of the parotid gland: immunohistochemical and molecular analysis of two cases. Mod Pathol 13:554–561
Nagao T, Sugano I, Matsuzaki O, et al. (2000) Intraductal papillary tumors of the major salivary glands: case reports of benign and malignant variants. Arch Pathol Lab Med 124:291–295
Namin AK, Moshref M, Shahoon H, et al. (2005) Intraosseous mucoepidermoid carcinoma of the maxilla in a teenager: a case report and review of literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 100:e93–96
Nasse D (1892) Die Geschwulste der Speicheldrusen und verwandte Tumoren des Kopfes. Langenbecks Arch Klin Chir 44:233–302
Nessan VJ, Jacoway JR (1979) Biopsy of minor salivary glands in the diagnosis of sarcoidosis. N Engl J Med 301:922–924
Neto AG, Pineda-Daboin K, Spencer ML, et al. (2005) Sinonasal acinic cell carcinoma: a clinicopathologic study of four cases. Head Neck 27:603–607
Nguyen LH, Black MJ, Hier M, et al. (2003) HER2/neu and Ki-67 as prognostic indicators in mucoepidermoid carcinoma of salivary glands. J Otolaryngol 32:328–331
Nishimura T, Furukawa M, Kawahara E, et al. (1991) Differential diagnosis of pleomorphic adenoma by immunohistochemical means. J Laryngol Otol 105:1057–1060
Nistal M, Garcia-Viera M, Martinez-Garcia C, et al. (1994) Epithelial-myoepithelial tumor of the bronchus. Am J Surg Pathol 18:421–425
Nordkvist A, Mark J, Dahlenfors R, et al. (1994) Cytogenetic observations in 13 cystadenolymphomas (Warthin’s tumors). Cancer Genet Cytogenet 76:129–135
Nordkvist A, Roijer E, Bang G, et al. (2000) Expression and mutation patterns of p53 in benign and malignant salivary gland tumors. Int J Oncol 16:477–483
Norlin R (1965) Bilateral mixed tumor of the parotid initially regarded as pharyngeal neoplasm. Pract Otorhinolaryngol (Basel) 27:298–301
Ochel HJ, Gademann G, Rocken C, et al. (2005) Effects of imatinib mesylate on adenoid cystic carcinomas. Anticancer Res 25:3659–3664
Ockner DM, Mills SE, Swanson PE, et al. (1994) Salivary duct carcinoma: An immunohistologic comparison with invasive ductal carcinoma of the breast. Lab Invest 70:100A
Ogawa I, Nikai H, Takata T, et al. (1992) Clear-cell variant of mucoepidermoid carcinoma: report of a case with immunohistochemical and ultrastructural observations. J Oral Maxillofac Surg 50:906–910
Olsen KD, Lewis JE (2001) Carcinoma ex pleomorphic adenoma: a clinicopathologic review. Head Neck 23:705–712
Olsen KD, Maragos NE, Weiland LH (1980) First branchial cleft anomalies. Laryngoscope 90:423–436
Orlian AI, Salman L, Reddi T, et al. (1987) Sebaceous adenoma of the oral mucosa. J Oral Med 42:38–39
Ortiz-Hidalgo C, Cervantes J, de la Vega G (1995) Unilateral polycystic (dysgenetic) disease of the parotid gland. South Med J 88:1173–1175
Orvidas LJ, Kasperbauer JL, Lewis JE, et al. (2000) Pediatric parotid masses. Arch Otolaryngol Head Neck Surg 126:177–184
Osial TA Jr., Whiteside TL, Buckingham RB, et al. (1983) Clinical and serologic study of Sjogren’s syndrome in patients with progressive systemic sclerosis. Arthritis Rheum 26:500–508
Ozolek JA, Bastacky SI, Myers EN, et al. (2005) Immunophenotypic comparison of salivary gland oncocytoma and metastatic renal cell carcinoma. Laryngoscope 115:1097–1100
Padberg B-C, Sasse B, Huber A, et al. (2005) Sarcomatoid salivary duct carcinoma. Ann Diagn Pathol 9:86–92
Pai RR, Bharathi S, Naik R, et al. (1994) Unilocular cystic sebaceous lymphadenoma of the parotid gland. Indian J Pathol Microbiol 37:327–330
Peel R (2001) Diseases of the salivary gland. Surgical pathology of the head and neck. Edited by Barnes L. New York, Marcel-Dekker, pp 634–690
Penner CR, Folpe AL, Budnick SD (2002) C-kit expression distinguishes salivary gland adenoid cystic carcinoma from polymorphous low-grade adenocarcinoma. Mod Pathol 15:687–691
Perez-Ordonez B, Linkov I, Huvos AG (1998) Polymorphous low-grade adenocarcinoma of minor salivary glands: a study of 17 cases with emphasis on cell differentiation. Histopathology 32:521–529
Perzin KH, LiVolsi VA (1979) Acinic cell carcinomas arising in salivary glands: a clinicopathologic study. Cancer 44:1434–1457
Pesavento G, Ferlito A, Recher G (1980) Primary clear cell carcinoma of the larynx. J Clin Pathol 33:1160–1164
Piattelli A, Tete S (1995) Lymphoepithelial cyst of the parotid gland. Acta Stomatol Belg 92:137–138
Pinkston JA, Cole P (1996) Cigarette smoking and Warthin’s tumor. Am J Epidemiol 144:183–187
Pires FR, da Cruz Perez DE, de Almeida OP, et al. (2004) Estrogen receptor expression in salivary gland mucoepidermoid carcinoma and adenoid cystic carcinoma. Pathol Oncol Res 10:166–168
Pires FR, de Almeida OP, de Araujo VC, et al. (2004) Prognostic factors in head and neck mucoepidermoid carcinoma. Arch Otolaryngol Head Neck Surg 130:174–180
Puxeddu R, Puxeddu P, Parodo G, et al. (1998) Polymorphous low-grade adenocarcinoma of the parotid gland. Eur J Morphol 36(suppl):262–266
Quddus MR, Henley JD, Affify AM, et al. (1999) Basal cell adenocarcinoma of the salivary gland: an ultrastructural and immunohistochemical study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 87:485–492
Raad, II, Sabbagh MF, Caranasos GJ (1990) Acute bacterial sialadenitis: a study of 29 cases and review. Rev Infect Dis 12:591–601
Rapidis AD, Givalos N, Gakiopoulou H, et al. (2005) Adenoid cystic carcinoma of the head and neck. Clinicopathological analysis of 23 patients and review of the literature. Oral Oncol 41:328–335
Raslan WF, Sawyer DR, Mercuri LG (1998) Central mucoepidermoid carcinoma. J Can Dent Assoc 64:420–424
Reis-Filho JS, Schmitt FC (2002) Taking advantage of basic research: p63 is a reliable myoepithelial and stem cell marker. Adv Anat Pathol 9:280–289
Renehan A, Gleave EN, McGurk M (1996) An analysis of the treatment of 114 patients with recurrent pleomorphic adenomas of the parotid gland. Am J Surg 172:710–714
Richardson RL, Weiland LH (1982) Undifferentiated small cell carcinomas in extrapulmonary sites. Semin Oncol 9:484–496
Righi PD, Li YQ, Deutsch M, et al. (1994) The role of the p53 gene in the malignant transformation of pleomorphic adenomas of the parotid gland. Anticancer Res 14:2253–2257
Ritland F, Lubensky I, LiVolsi VA (1993) Polymorphous low-grade adenocarcinoma of the parotid salivary gland. Arch Pathol Lab Med 117:1261–1263
Robin C, Laboulbene A (1853) Memoire sur trois productions morbides non decrites. C R Soc Biol 5:185–196
Rodriguez J, Forcelledo M, Gutierrez L, et al. (2004) Small cell undifferentiated carcinoma of the submandibular gland with neurosecretory features. Ann Otol Rhinol Laryngol 113:55–59
Rollins CE, Yost BA, Costa MJ, et al. (1995) Squamous differentiation in small-cell carcinoma of the parotid gland. Arch Pathol Lab Med 119:183–185
Romagosa V, Bella MR, Truchero C, et al. (1992) Necrotizing sialometaplasia (adenometaplasia) of the trachea. Histopathology 21:280–282
Rosai J (1996) Major and minor salivary glands. Ackerman’s surgical pathology. Edited by Rosai J. St. Louis, Mosby, pp 834–835
Rousseau A, Mock D, Dover DG, et al. (1999) Multiple canalicular adenomas: a case report and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 87:346–350
Rye LA, Calhoun NR, Redman RS (1980) Necrotizing sialometaplasia in a patient with Buerger’s disease and Raynaud’s phenomenon. Oral Surg Oral Med Oral Pathol 49:233–236
Said S, Compana J (2005) Myoepithelial carcinoma ex-pleomorphic adenoma of salivary glands: A problematic diagnosis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 99:196–201
Sakorafas GH, Sarr MG, van de Velde CJ, et al. (2005) Intraductal papillary mucinous neoplasms of the pancreas: A surgical perspective. Surg Oncol 14:155–178
Saksela E, Tarkkanen J, Kohonen A (1970) The malignancy of mixed tumors of the parotid gland. A clinicopathological analysis of 70 cases. Acta Otolaryngol 70:62–70
Saksela E, Tarkkanen J, Wartiovaara J (1972) Parotid clear-cell adenoma of possible myoepithelial origin. Cancer 30:742–748
Santucci L, Smorlesi L (1954) [I tumori misti, benigni e maligni, di tipo salivare, in sede extra-macro-salivare con particolare riguardo alle localizzazioni eccezionali.]. Arch De Vecchi Anat Patol 22:623–692
Santucci M, Gallo O, Calzolari A, et al. (1993) Detection of Epstein-Barr viral genome in tumor cells of Warthin’s tumor of parotid gland. Am J Clin Pathol 100:662–665
Sato T, Kamata SE, Kawabata K, et al. (2005) Acinic cell carcinoma of the parotid gland in a child. Pediatr Surg Int 21:377–380
Savera AT, Sloman A, Huvos AG, et al. (2000) Myoepithelial carcinoma of the salivary glands: a clinicopathologic study of 25 patients. Am J Surg Pathol 24:761–774
Schoning H, Emshoff R, Kreczy A (1998) Necrotizing sialometaplasia in two patients with bulimia and chronic vomiting. Int J Oral Maxillofac Surg 27:463–465
Schultz AM, Thomas AB, Henley JD, et al. (2004) Pathologic quiz case: a 42-year-old man with right facial swelling and weakness. Dedifferentiated acinic cell carcinoma of the parotid gland. Arch Pathol Lab Med 128:e52–53
Sciubba JJ, Brannon RB (1982) Myoepithelioma of salivary glands: report of 23 cases. Cancer 49:562–572
Seaver PR Jr., Kuehn PG (1979) Adenoid cystic carcinoma of the salivary glands. A study of ninety-three cases. Am J Surg 137:449–455
Seethala RR, LiVolsi VA, Zhang PJ, et al. (2005) Comparison of p63 and p73 expression in benign and malignant salivary gland lesions. Head Neck 27:696–702
Seifert G (1991) Histologic Typing of Salivary Gland Tumors. Springer, New York p 26
Seifert G (1996) Classification and differential diagnosis of clear and basal cell tumors of the salivary glands. Semin Diagn Pathol 13:95–103
Seifert G (1997) Aetiological and histological classification of sialadenitis. Pathologica 89:7–17
Seifert G (1997) [Carcinoma in pre-existing Warthin tumors (cystadenolymphoma) of the parotid gland. Classification, pathogenesis and differential diagnosis]. Pathologe 18:359–367
Seifert G (1998) Are adenomyoepithelioma of the breast and epithelial-myoepithelial carcinoma of the salivary glands identical tumours? Virchows Arch 433:285–288
Seifert G, Bull HG, Donath K (1980) Histologic subclassification of the cystadenolymphoma of the parotid gland. Analysis of 275 cases. Virchows Arch A Pathol Anat Histol 388:13–38
Seifert G, Donath K (1976) Classification of the pathohistology of diseases of the salivary glands — review of 2,600 cases in the Salivary Gland Register. Beitr Pathol 159:1–32
Seifert G, Donath K (1996) Multiple tumours of the salivary glands — terminology and nomenclature. Eur J Cancer B Oral Oncol 32B:3–7
Seifert G, Donath K, Schafer R (1999) Lipomatous pleomorphic adenoma of the parotid gland. Classification of lipomatous tissue in salivary glands. Pathol Res Pract 195:247–252
Seifert G, Miehlke A, Haubrich J, et al. (1986) Diseases of the Salivary Glands: Diagnosis, Pathology, Treatment, Facial Nerve Surgery, Stuttgart, Georg Theime Verlag, pp 248–252
Seifert G, Thomsen S, Donath K (1981) Bilateral dysgenetic polycystic parotid glands. Morphological analysis and differential diagnosis of a rare disease of the salivary glands. Virchows Arch A Pathol Anat Histol 390:273–288
Selva D, Davis GJ, Dodd T, et al. (2004) Polymorphous low-grade adenocarcinoma of the lacrimal gland. Arch Ophthalmol 122:915–917
Shemen LJ, Huvos AG, Spiro RH (1987) Squamous cell carcinoma of salivary gland origin. Head Neck Surg 9:235–240
Shimoda M, Kameyama K, Morinaga S, et al. (2004) Malignant transformation of sialadenoma papilliferum of the palate: a case report. Virchows Arch 445:641–646
Silvers AR, Som PM (1998) Salivary glands. Radiol Clin North Am 36:941–966, vi
Simpson RH, Clarke TJ, Sarsfield PT, et al. (1991) Epithelial-myoepithelial carcinoma of salivary glands. J Clin Pathol 44:419–423
Simpson RHW, Eveson JW (2005) Warthin tumor. Pathology and Classification of Head and Neck Tumours. Edited by Barnes EL, Eveson JW, Sidransky D. Lyons, IARC, pp 263–265
Simpson RHW, Prasad AR, Lewis JE, et al. (2003) Mucinrich variant of salivary duct carcinoma: a clinicopathologic and immunohistochemical study of four cases. Am J Surg Pathol 27:1070–1079
Sjogren H, Dahlenfors R, Stenman G, et al. (2003) Observations by G-banding and multicolor spectral karyotyping in a salivary gland basal cell adenoma. Virchows Arch 442:86–87
Skalova A, Gnepp DR, Simpson RH, et al. (2006) Clonal Nature of Sclerosing Polycystic Adenosis of Salivary Glands Demonstrated by Using the Polymorphism of the Human Androgen Receptor Locus (HUMARA) as a Marker. Mod Pathol 19:105A
Skalova A, Leivo I, Von Boguslawsky K, et al. (1994) Cell proliferation correlates with prognosis in acinic cell carcinomas of salivary gland origin. Immunohistochemical study of 30 cases using the MIB 1 antibody in formalin-fixed paraffin sections. J Pathol 173:13–21
Skalova A, Leivo I, Wolf H, et al. (2000) Oncocytic cystadenoma of the parotid gland with tyrosine-rich crystals. Pathol Res Pract 196:849–851
Skalova A, Michal M (2005) Cystadenoma. Pathology and Classification of Head and Neck Tumours. Edited by Barnes EL, Eveson JW, Sidransky D. Lyons, IARC, pp 273–274
Skalova A, Michal M, Ryska A, et al. (1999) Oncocytic myoepithelioma and pleomorphic adenoma of the salivary glands. Virchows Arch 434:537–546
Skalova A, Michal M, Simpson RH, et al. (2002) Sclerosing polycystic adenosis of parotid gland with dysplasia and ductal carcinoma in situ. Report of three cases with immunohistochemical and ultrastructural examination. Virchows Arch 440:29–35
Skalova A, Simpson RH, Lehtonen H, et al. (1997) Assessment of proliferative activity using the MIB1 antibody help to distinguish polymorphous low grade adenocarcinoma from adenoid cystic carcinoma of salivary glands. Pathol Res Pract 193:695–703
Skalova A, Starek I, Simpson RH, et al. (2001) Spindle cell myoepithelial tumours of the parotid gland with extensive lipomatous metaplasia. A report of four cases with immunohistochemical and ultrastructural findings. Virchows Arch 439:762–767
Skalova A, Starek I, Vanecek T, et al. (2003) Expression of HER-2/neu gene and protein in salivary duct carcinomas of parotid gland as revealed by fluorescence in-situ hybridization and immunohistochemistry. [see comment]. Histopathology 42:348–356
Slootweg PJ (1993) Low-grade adenocarcinoma of the oral cavity: polymorphous or papillary? J Oral Pathol Med 22:327–330
Slootweg PJ, Muller H (1987) Low-grade adenocarcinoma of the oral cavity. A comparison between the terminal duct and the papillary type. J Craniomaxillofac Surg 15:359–364
Smith A, Winkler B, Perzin KH, et al. (1985) Mucoepidermoid carcinoma arising in an intraparotid lymph node. Cancer 55:400–403
Smith BC, Ellis GL, Slater LJ, et al. (1996) Sclerosing polycystic adenosis of major salivary glands. A clinicopathologic analysis of nine cases. Am J Surg Pathol 20:161–170
Smith JA, Warhol MJ, Brodsky GL (1983) An immunohistochemical study of a carcinoma of the parotid gland exhibiting both ductal and acinic cell differentiation. Oral Surg Oral Med Oral Pathol 55:267–273
Smyth AG, Ward-Booth RP, High AS (1993) Polycystic disease of the parotid glands: two familial cases. Br J Oral Maxillofac Surg 31:38–40
Snyderman C, Johnson JT, Barnes EL (1986) Extraparotid Warthin’s tumor. Otolaryngol Head Neck Surg 94:169–175
Som PM, Biller HF (1992) Kimura disease involving parotid gland and cervical nodes: CT and MR findings. J Comput Assist Tomogr 16:320–322
Soofer SB, Tabbara S (1999) Intraductal papilloma of the salivary gland. A report of two cases with diagnosis by fine needle aspiration biopsy. Acta Cytol 43:1142–1146
Spies JW (1930) Adenoid cystic carcinoma. Arch Surg 21:365–404
Spiro RH (1986) Salivary neoplasms: overview of a 35-year experience with 2,807 patients. Head Neck Surg 8:177–184
Spiro RH, Huvos AG, Strong EW (1977) Malignant mixed tumor of salivary origin: a clinicopathologic study of 146 cases. Cancer 39:388–396
Spiro RH, Huvos AG, Strong EW (1978) Acinic cell carcinoma of salivary origin. A clinicopathologic study of 67 cases. Cancer 41:924–935
Spiro RH, Huvos AG, Strong EW (1979) Adenoid cystic carcinoma: factors influencing survival. Am J Surg 138:579–583
Spiro RH, Huvos AG, Strong EW (1982) Adenocarcinoma of salivary origin. Clinicopathologic study of 204 patients. Am J Surg 144:423–431
Spiro RH, Koss LG, Hajdu SI, et al. (1973) Tumors of minor salivary origin. A clinicopathologic study of 492 cases. Cancer 31:117–129
Stanley RJ, Weiland LH, Olsen KD, et al. (1988) Dedifferentiated acinic cell (acinous) carcinoma of the parotid gland. Otolaryngol Head Neck Surg 98:155–161
Stell PM (1986) Adenoid cystic carcinoma. Clin Otolaryngol 11:267–291
Stephen J, Batsakis JG, Luna MA, et al. (1986) True malignant mixed tumors (carcinosarcoma) of salivary glands. Oral Surg Oral Med Oral Pathol 61:597–602
Stephen J, Luna MA, Batsakis J (1985) Malignant mixed (heterologous) tumors of salivary glands. Lab Invest 52:65A
Sterman BM, Kraus DH, Sebek BA, et al. (1990) Primary squamous cell carcinoma of the parotid gland. Laryngoscope 100:146–148
Stewart FW, Foote FW, Becker WF (1945) Mucoepidermoid tumors of salivary glands. Ann Surg 122:820–844
Stewart S, Levy R, Karpel J, et al. (1974) Lymphoepithelial (branchial) cyst of the parotid gland. J Oral Surg 32:100–106
Streubel B, Simonitsch-Klupp I, Mullauer L, et al. (2004) Variable frequencies of MALT lymphoma-associated genetic aberrations in MALT lymphomas of different sites. Leukemia 18:1722–1726
Suarez P, Hammond HL, Luna MA, et al. (1998) Palatal canalicular adenoma: report of 12 cases and review of the literature. Ann Diagn Pathol 2:224–228
Szanto PA, Luna MA, Tortoledo ME, et al. (1984) Histologic grading of adenoid cystic carcinoma of the salivary glands. Cancer 54:1062–1069
Tabak LA (1995) In defense of the oral cavity: structure, biosynthesis, and function of salivary mucins. Annu Rev Physiol 57:547–564
Tabak LA, Levine MJ, Mandel ID, et al. (1982) Role of salivary mucins in the protection of the oral cavity. J Oral Pathol 11:1–17
Takai Y, Dardick I, Mackay A, et al. (1995) Diagnostic criteria for neoplastic myoepithelial cells in pleomorphic adenomas and myoepitheliomas. Immunocytochemical detection of muscle-specific actin, cytokeratin 14, vimentin, and glial fibrillary acidic protein. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 79:330–341
Takai Y, Mori M, Dardick I, et al. (1994) Myofilament localization and immunoelectron microscopic detection of muscle-specific actin in neoplastic myoepithelial cells in pleomorphic adenomas and myoepitheliomas. Ultrastruct Pathol 18:575–591
Takeda Y, Shimono M (1999) Pleomorphic adenoma with nuclear palisading arrangement of modified myoepithelial cells: histopathologic and immunohistochemical study. Bull Tokyo Dent Coll 40:27–34
Tauxe WN, Mc DJ, Devine KD (1962) A century of cylindromas. Short review and report of 27 adenoid cystic carcinomas arising in the upper respiratory passages. Arch Otolaryngol 75:364–376
Tavassoli FA (1991) Myoepithelial lesions of the breast. Myoepitheliosis, adenomyoepithelioma, and myoepithelial carcinoma. Am J Surg Pathol 15:554–568
Tay HL, Reilly PG, Akosa AB (1992) Salivary terminal duct carcinoma. J Laryngol Otol 106:649–651
Terada T, Ikeuchi S, Inomoto C, et al. (2004) Mucoepidermoid carcinoma of the palate composed exclusively of clear cells (clear cell variant). Virchows Arch 445:541–543
Terry JH, Loree TR, Thomas MD, et al. (1991) Major salivary gland lymphoepithelial lesions and the acquired immunodeficiency syndrome. Am J Surg 162:324–329
Teymoortash A, Simolka N, Schrader C, et al. (2005) Lymphocyte subsets in irradiation-induced sialadenitis of the submandibular gland. Histopathology 47:493–500
Teymoortash A, Werner JA (2005) Tissue that has lost its track: Warthin’s tumour. Virchows Arch 446:585–588
Thackray A, Lucas R (1974) Tumors of the Major Salivary Glands. Atlas of Tumor Pathology, Series 2, Fascicle 10. Washington, DC, Armed Forces Institute of Pathology, pp 107–117
Thompson AS, Bryant HC Jr. (1950) Histogenesis of papillary cystadenoma lymphomatosum (Warthin’s tumor) of the parotid salivary gland. Am J Pathol 26:807–849
Tortoledo ME, Luna MA, Batsakis JG (1984) Carcinomas ex pleomorphic adenoma and malignant mixed tumors. Histomorphologic indexes. Arch Otolaryngol 110:172–176
Toynton S, Wilkins M, Cook H, et al. (1994) True malignant mixed tumor of a minor salivary gland. J Laryngol Otol 108:76–79
Tralongo V, Becchina G, Genovese F, et al. (2002) Polymorphous low-grade adenocarcinoma of the salivary glands: clinicopathological and immunohistochemical study of a case. Anticancer Res 22:1347–1352
Tralongo V, Daniele E (1998) Epithelial-myoepithelial carcinoma of the salivary glands: a review of literature. Anticancer Res 18:603–608
Tralongo V, Rodolico V, Nagar C, et al. (1997) Epithelialmyoepithelial carcinoma of the salivary glands: a clinicopathologic, immunohistochemical and DNA flow cytometric study of three cases. Anticancer Res 17:761–768
Tran PT, Cunningham CJ, Baughman RA (2004) Glandular odontogenic cyst. J Endod 30:182–184
Triglia JM, Nicollas R, Ducroz V, et al. (1998) First branchial cleft anomalies: a study of 39 cases and a review of the literature. Arch Otolaryngol Head Neck Surg 124:291–295
Trompouki E, Hatzivassiliou E, Tsichritzis T, et al. (2003) CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members. Nature 424:793–796
Tsang YW, Tung Y, Chan JK (1991) Polymorphous low grade adenocarcinoma of the palate in a child. J Laryngol Otol 105:309–311
Tschen JA, McGavran MH (1979) Sebaceous lymphadenoma: ultrastructural observations and lipid analysis. Cancer 44:1388–1392
Tucci FM, Bianchi PM, Bottero S, et al. (1993) Acinic cell carcinoma of the parotid gland in childhood. Int J Pediatr Otorhinolaryngol 27:187–191
Tuncel U, Ergul G, Ozlugedik S, et al. (2004) Myoepithelial carcinoma in the nasopharynx: an unusual localization. Yonsei Med J 45:161–165
Tytor M, Gemryd P, Grenko R, et al. (1995) Adenoid cystic carcinoma: significance of DNA ploidy. Head Neck 17:319–327
Ubaidat MA, Robinson RA, Belding PJ, et al. (2001) Sialadenoma papilliferum of the hard palate: report of 2 cases and immunohistochemical evaluation. Arch Pathol Lab Med 125:1595–1597
Uccini S, Riva E, Antonelli G, et al. (1999) The benign cystic lymphoepithelial lesion of the parotid gland is a viral reservoir in HIV type 1-infected patients. AIDS Res Hum Retroviruses 15:1339–1344
Urano M, Abe M, Horibe Y, et al. (2002) Sclerosing mucoepidermoid carcinoma with eosinophilia of the salivary glands. Pathol Res Pract 198:305–310
Urban SD, Hall JM, Bentkover SH, et al. (2002) Salivary duct carcinoma of minor salivary gland origin: report of a case involving the cavernous sinus. J Oral Maxillofac Surg 60:958–962
van der Schans EJ, Knegt P, de Jong PC, et al. (1985) Adenoid cystic carcinoma of the upper digestive and respiratory tracts. A retrospective study of 59 cases. Clin Otolaryngol 10:63–67
van der Wal JE, Davids JJ, van der Waal I (1993) Extraparotid Warthin’s tumours — report of 10 cases. Br J Oral Maxillofac Surg 31:43–44
van der Wal JE, Kraaijenhagen HA, van der Waal I (1995) Subacute necrotising sialadenitis: a new entity? Br J Oral Maxillofac Surg 33:302–303
van der Wal JE, Snow GB, van der Waal I (1990) Intraoral adenoid cystic carcinoma. The presence of perineural spread in relation to site, size, local extension, and metastatic spread in 22 cases. Cancer 66:2031–2033
van der Walt JD, Leake J (1987) Granulomatous sialadenitis of the major salivary glands. A clinicopathological study of 57 cases. Histopathology 11:131–144
Van Heerden WF, Raubenheimer EJ, Dreyer L (2005) The role of DNA ploidy and Ki-67 in the grading of mucoepidermoid carcinomas. Anticancer Res 25:2589–2592
Van Krieken JH (1993) Prostate marker immunoreactivity in salivary gland neoplasms. A rare pitfall in immunohistoch emistry.[see comment]. Am J Surg Pathol 17:410–414
Van Roggen G, Baatenburg-De J, Verschuur B, et al. (1998) Myoepithelial carcinoma (malignant myoepithelioma): First report of an occurrence in the maxillary sinus. Histopathology 32:239–241
Verghese S, Lalitha MK (1975) Sebaceous lymphadenoma of the parotid region report of a case. Indian J Pathol Bacteriol 18:46–48
Vicandi B, Jimenez-Heffernan JA, Lopez-Ferrer P, et al. (1999) HIV-1 (p24)-positive multinucleated giant cells in HIV-associated lymphoepithelial lesion of the parotid gland. A report of two cases. Acta Cytol 43:247–251
Vincent SD, Hammond HL, Finkelstein MW (1994) Clinical and therapeutic features of polymorphous low-grade adenocarcinoma. Oral Surg Oral Med Oral Pathol 77:41–47
Voz ML, Agten NS, Van de Ven WJ, et al. (2000) PLAG1, the main translocation target in pleomorphic adenoma of the salivary glands, is a positive regulator of IGF-II. Cancer Res 60:106–113
Voz ML, Astrom AK, Kas K, et al. (1998) The recurrent translocation t(5;8)(p13;q12) in pleomorphic adenomas results in upregulation of PLAG1 gene expression under control of the LIFR promoter. Oncogene 16:1409–1416
Vrielinck LJ, Ostyn F, van Damme B, et al. (1988) The significance of perineural spread in adenoid cystic carcinoma of the major and minor salivary glands. Int J Oral Maxillofac Surg 17:190–193
Waldron CA, el-Mofty SK, Gnepp DR (1988) Tumors of the intraoral minor salivary glands: a demographic and histologic study of 426 cases. Oral Surg Oral Med Oral Pathol 66:323–333
Waldron CA, Koh ML (1990) Central mucoepidermoid carcinoma of the jaws: report of four cases with analysis of the literature and discussion of the relationship to mucoepidermoid, sialodontogenic, and glandular odontogenic cysts. J Oral Maxillofac Surg 48:871–877
Wang C-P, Chang Y-L, Ko J-Y, et al. (2004) Lymphoepithelial carcinoma versus large cell undifferentiated carcinoma of the major salivary glands. Cancer 101:2020–2027
Warrick PD, Irish JC, Mancer K, et al. (2000) Basal cell adenocarcinoma: a rare malignancy of the salivary glands. J Otolaryngol 29:102–109
Warthin AS (1929) Papillary cystadenoma lymphomatosum. A rare teratoid of the parotid. J Cancer Res 13:116–125
Wasan SM (1971) Sebaceous lymphadenoma of the parotid gland. Cancer 28:1019–1022
Weber A, Langhanki L, Schutz A, et al. (2002) Expression profiles of p53, p63, and p73 in benign salivary gland tumors. Virchows Arch 441:428–436
Weed D, Gomez-Fernancez C, Pacheo J, et al. (2004) MUC4 and ERBB2 expression in major and minor salivary gland mucoepidermoid carcinoma. Head Neck 26:353–364
Weitzner S (1973) Lymphoepithelial (branchial) cyst of parotid gland. Oral Surg Oral Med Oral Pathol 35:85–88
Wenig BM, Harpaz N, DelBridge C (1989) Polymorphous low-grade adenocarcinoma of seromucous glands of the nasopharynx. A report of a case and a discussion of the morphologic and immunohistochemical features. Am J Clin Pathol 92:104–109
Wenig BM, Hitchcock CL, Ellis GL, et al. (1992) Metastasizing mixed tumor of salivary glands. A clinicopathologic and flow cytometric analysis. Am J Surg Pathol 16:845–858
Wermuth DJ, Mann CH, Odere F (1988) Metastasizing pleomorphic adenoma arising in the soft palate. Otolaryngol Head Neck Surg 99:505–508
Werning JT, Waterhouse JP, Mooney JW (1990) Subacute necrotizing sialadenitis. Oral Surg Oral Med Oral Pathol 70:756–759
Whitaker SB, Vigneswaran N, Singh BB (1997) Androgen receptor status of the oral sebaceous glands. Am J Dermatopathol 19:415–418
White DK, Miller AS, McDaniel RK, et al. (1982) Inverted ductal papilloma: a distinctive lesion of minor salivary gland. Cancer 49:519–524
Whittaker JS, Turner EP (1976) Papillary tumours of the minor salivary glands. J Clin Pathol 29:795–805
Williams SB, Ellis GL, Auclair PL (1993) Immunohistochemical analysis of basal cell adenocarcinoma. Oral Surg Oral Med Oral Pathol 75:64–69
Williamson JD, Simmons BH, el-Naggar A, et al. (2000) Mucoepidermoid carcinoma involving Warthin tumor. A report of five cases and review of the literature. Am J Clin Pathol 114:564–570
Wilson DF, Robinson BW (1984) Oral inverted ductal papilloma. Oral Surg Oral Med Oral Pathol 57:520–523
Winkle MR, Harrington PC, Maronian N (1999) Central mucoepidermoid carcinoma of the mandible. Am J Otolaryngol 20:169–171
Wu LY, Cheng J, Lu Y, et al. (2004) [Epstein-Barr virus infection in benign lymphoepithelial lesions with malignant transformation of salivary glands]. Zhonghua Kou Qiang Yi Xue Za Zhi 39:291–293
Wuketich S, Kittinger G (1966) [Sebaceous lymphadenoma of the parotid]. Arch Klin Exp Ohren Nasen Kehlkopfheilkd 187:836–844
Yu G, Ussmueller J, Donath K (2000) [A clinicopathologic study on membranous basal cell adenoma]. Zhonghua Kou Qiang Yi Xue Za Zhi 35:88–90
Yu G, Ussmueller J, Donath K (2000) [Histogenesis and development of membranous basal cell adenoma of the salivary gland]. Zhonghua Kou Qiang Yi Xue Za Zhi 35:31–33
Yu GY, Ma DQ, Zhang Y, et al. (2004) Multiple primary tumours of the parotid gland. Int J Oral Maxillofac Surg 33:531–534
Yu GY, Ubmuller J, Donath K (1998) Membranous basal cell adenoma of the salivary gland: a clinicopathologic study of 12 cases. Acta Otolaryngol 118:588–593
Zarbo RJ (2002) Salivary gland neoplasia: a review for the practicing pathologist. Mod Pathol 15:298–323
Zarbo RJ, Prasad AR, Regezi JA, et al. (2000) Salivary gland basal cell and canalicular adenomas: immunohistochemical demonstration of myoepithelial cell participation and morphogenetic considerations. Arch Pathol Lab Med 124:401–405
Zarbo RJ, Regezi JA, Lloyd RV, et al. (1987) HLA-DR antigens in normal, inflammatory, and neoplastic salivary glands. Oral Surg Oral Med Oral Pathol 64:577–584
Zhao M, Takata T, Ogawa I, et al. (1998) Immunohistochemical demonstration of bone morphogenetic protein-2 and type II collagen in pleomorphic adenoma of salivary glands. J Oral Pathol Med 27:293–296
Zschoch H (1992) [Mucus gland infarct with squamous epithelial metaplasia in the lung. A rare site of so-called necrotizing sialometaplasia]. Pathologe 13:45–48
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Peel, R.L., Seethala, R.R. (2007). Pathology of Salivary Gland Disease. In: Myers, E.N., Ferris, R.L. (eds) Salivary Gland Disorders. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-47072-4_3
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