Overview
- Provides up-to-date information on glycoscience, linking basic biology and clinical applications
- Presents new results, approaches, and research directions
- Ideal guide to the field for students and young researchers
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About this book
This book, now in an extensively revised second edition, provides a comprehensive summary of the latest knowledge regarding glycosignals and a thorough analysis of their involvement in not only cancers but also other refractory conditions such as chronic inflammatory disorders. Many relevant topics are covered, including the search for novel tumor epitopes related to carbohydrates, the assembly of glycoconjugates, the modulation of signaling pathways by glycosylation, and interactions between complex carbohydrates and their recognition molecules. The role of various research approaches, for example advanced mass spectrometry, high-resolution imaging, and bioinformatics, is closely examined, and the results of novel therapeutic trials targeting glycosignals are discussed. The book will be essential reading for students and young researchers with an interest in glycoscience. In presenting new results and approaches and identifying areas for future research, it will also be of benefitfor specialists in the field.
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Keywords
Table of contents (10 chapters)
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Search for Novel Tumor Epitopes Related to Carbohydrates
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Assembly of Glycoconjugates
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Signaling Pathways Modulated by Glycosylation
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Interaction Between Carbohydrate and Carbohydrate-Recognizing Molecules
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Clinical Trials Targeting Glycosignals
Editors and Affiliations
About the editors
College of Life and Health Sciences, Chubu University, Japan
Minoru Fukuda
Cancer Research Center, Standford-Burnham Medical Research Institute La Jolla, CA, USA
Bibliographic Information
Book Title: Glycosignals in Cancer
Book Subtitle: Molecular Assembly and Recognition
Editors: Koichi Furukawa, Minoru Fukuda
DOI: https://doi.org/10.1007/978-981-19-7732-9
Publisher: Springer Singapore
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Nature Singapore Pte Ltd. 2023
Hardcover ISBN: 978-981-19-7731-2Published: 21 March 2023
Softcover ISBN: 978-981-19-7734-3Published: 22 March 2024
eBook ISBN: 978-981-19-7732-9Published: 20 March 2023
Edition Number: 2
Number of Pages: VI, 238
Number of Illustrations: 1 b/w illustrations
Topics: Cancer Research, Human Genetics, Biochemistry, general, Cell Biology, Oncology