Overview
- Provides detailed guidelines for molecular analysis of archive tissues
- An invaluable aid for researchers and pathologists involved in translational research and diagnostics
- Caters for the needs of the less experienced through the inclusion of clear notes and explanations
- Written by experts who have developed the described methods and validated them within the framework of a multi-institution European project
- Includes supplementary material: sn.pub/extras
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About this book
A huge amount of fixed and paraffin-embedded tissue is stored in every hospital. This is very precious material that can be used for translational research and for diagnostics. The molecular methods employed for analysis of these tissues are similar to the usual molecular biology and proteomics methods, but reliable results can be obtained only if specific steps are followed with great care. This book provides detailed and precise guidelines for molecular analysis of archive tissues and will serve as an invaluable aid for researchers and pathologists involved in translational research and diagnostics. Clear notes and explanations are included to simplify use of the protocols for the less experienced. The authors are a group of acknowledged experts who have developed the described methods and validated them within the European project "Archive Tissues: Improving Molecular Medicine Research and Clinical Practice - IMPACTS", which has involved 21 leading institutions in 11 countries.
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Keywords
Table of contents (52 chapters)
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Archive Tissues
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Dissection of Tissue Components
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Extraction, Purification, Quantification and Quality Assessment of Nucleic Acids
Reviews
From the reviews:
“This is a valuable resource that provides precise guidelines for molecular analysis of archive tissues essential for pathologists and researchers involved in translational research and diagnostics. … students, laboratory technicians, and physician-scientists interested in molecular analysis of archive tissues will find this book useful. … The clear explanations should enable even less experienced researchers to follow the protocols.” (Omer Iqbal, Doody’s Review Service, December, 2011)Editors and Affiliations
About the editor
Bibliographic Information
Book Title: Guidelines for Molecular Analysis in Archive Tissues
Editors: Giorgio Stanta
DOI: https://doi.org/10.1007/978-3-642-17890-0
Publisher: Springer Berlin, Heidelberg
eBook Packages: Medicine, Medicine (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 2011
Hardcover ISBN: 978-3-642-17889-4Due: 27 June 2011
Softcover ISBN: 978-3-662-51984-4Published: 23 August 2016
eBook ISBN: 978-3-642-17890-0Published: 06 June 2011
Edition Number: 1
Number of Pages: XVI, 323
Topics: Pathology, Molecular Medicine, Oncology