Overview
- Focuses on new findings regarding the context dependency of cell signaling
- Shows that endocytosis provides an opportunity for modulating signaling networks’ output
- Provides an overview of the latest scientific insights on the role of endocytic trafficking and subcellular location in modulation
Part of the book series: Progress in Molecular and Subcellular Biology (PMSB, volume 57)
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About this book
This book focuses on the context dependency of cell signaling by showing how the endosomal system helps to structure and regulate signaling pathways. The location and concentration of signaling nodes regulate their activation cycles and engagement with distinct effector pathways. Whilst many cell signaling pathways are initiated from the cell surface, endocytosis provides an opportunity for modulating signaling networks’ output.
In this book, first a series of reviews describe the endocytic and endosomal system and show how these subcellular platforms sort and regulate a wide range of signaling pathway components and phenotypic outputs. The book then reviews the latest scientific insights into how endocytic trafficking and subcellular location modulate a set of major pathways that are essential to normal cellular function and organisms’ development.
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Keywords
Table of contents (11 chapters)
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Front Matter
Editors and Affiliations
Bibliographic Information
Book Title: Endocytosis and Signaling
Editors: Christophe Lamaze, Ian Prior
Series Title: Progress in Molecular and Subcellular Biology
DOI: https://doi.org/10.1007/978-3-319-96704-2
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer International Publishing AG, part of Springer Nature 2018
Hardcover ISBN: 978-3-319-96703-5Published: 23 August 2018
Softcover ISBN: 978-3-030-07234-6Published: 19 January 2019
eBook ISBN: 978-3-319-96704-2Published: 10 August 2018
Series ISSN: 0079-6484
Series E-ISSN: 2197-8484
Edition Number: 1
Number of Pages: VIII, 329
Number of Illustrations: 1 b/w illustrations, 27 illustrations in colour
Topics: Membrane Biology, Cell Physiology, Cell Cycle Analysis, Protein Science