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Rickettsiales

Biology, Molecular Biology, Epidemiology, and Vaccine Development

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  • © 2016

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Overview

Editors:
  1. Sunil Thomas

    1. Lankenau Institute for Medical Research, Wynnewood, USA

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  • Covers the 7 main genera: Anaplasma, Ehrlichia, Midichloria, Neorickettsia, Orientia, Rickettsia, and Wolbachia
  • Discusses novel vaccination strategies and therapies
  • Contributions by experts on Rickettsiales diseases

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About this book

Insect-transmitted rickettsiales diseases are significant sources of morbidity and mortality all over the world. Their incidence has been increasing in recent years in large part due to climate change and the movement of animals carrying the insect vectors. Currently there are no effective vaccines against diseases caused by members of the order Rickettsiales. Rickettsiales diseases are often misdiagnosed; this book is intended to serve as a tool for their understanding and diagnosis.

Rickettsiales covers the seven main genera: Anaplasma, Ehrlichia, Midichloria, Neorickettsia, Orientia, Rickettsia and Wolbachia. Discussion of each genus includes immunology and molecular biology of host-pathogen interactions, epidemiology and diagnosis, and vaccination strategies and therapies. 

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Table of contents (21 chapters)

  1. Front Matter

    Pages i-xvi
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  2. Rickettsiales: Importance and Taxonomy

    1. Front Matter

      Pages 1-1
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    2. The Importance of Rickettsiales Infections

      • Sunil Thomas, Walker Alexander, John Gilligan, Yasuko Rikihisa
      Pages 3-21
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    3. Molecular Epidemiology of Rickettsial Diseases

      • Marina E. Eremeeva
      Pages 23-57
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    4. Biodiversity of “Non-model” Rickettsiales and Their Association with Aquatic Organisms

      • Michele Castelli, Davide Sassera, Giulio Petroni
      Pages 59-91
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  3. Rickettsiales: Diagnosis and Management of Diseases

    1. Front Matter

      Pages 93-93
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    2. Rickettsiales: Laboratory Diagnosis

      • Lucas S. Blanton
      Pages 95-107
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    3. Rickettsiales: Treatment and Management of Human Disease

      • Lucas S. Blanton
      Pages 109-124
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    4. DHR-ICMR Guidelines for Diagnosis and Management of Rickettsial Diseases in India

      • Manju Rahi, M. D. Gupte, Anurag Bhargava, George M. Varghese, Rashmi Arora
      Pages 125-133
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  4. Anaplasma

    1. Front Matter

      Pages 135-135
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    2. Anaplasma phagocytophilum in Sheep

      • Erik Georg Granquist
      Pages 137-154
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  5. Ehrlichia

    1. Front Matter

      Pages 155-155
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    2. Exit Strategies of Ehrlichia

      • Sunil Thomas
      Pages 157-176
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    3. Development of Vaccines for Ehrlichiosis

      • Sunil Thomas
      Pages 177-196
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    4. Identification of T-Cell Epitopes in the Murine Host Response to Ehrlichia chaffeensis

      • Stephen K. Chapes, M. Teresa Ortega, Chuanmin Cheng, Roman R. Ganta
      Pages 197-214
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    5. Mutagenesis in Ehrlichia and Anaplasma Species: Its Application for Studies Focused on Understanding the Pathogenesis and Vaccine Development

      • Roman R. Ganta
      Pages 215-224
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    6. Epidemiology, Molecular Biology, and Pathogenic Mechanisms of Ehrlichia Infections

      • Xue-jie Yu, David H. Walker
      Pages 225-240
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    7. Ehrlichia ruminantium: The Causal Agent of Heartwater

      • Isabel Marcelino, Philippe Holzmuller, Frédéric Stachurski, Valérie Rodrigues, Nathalie Vachiéry
      Pages 241-280
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  6. Midichloria

    1. Front Matter

      Pages 281-281
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    2. Transmission of Members of the “Candidatus Midichloriaceae” Family to Vertebrates and Possible Involvement in Disease Pathogenesis

      • Michele Castelli, Una McCarthy, Giulio Petroni, Chiara Bazzocchi
      Pages 283-292
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Editors and Affiliations

  • Lankenau Institute for Medical Research, Wynnewood, USA

    Sunil Thomas

About the editor

Sunil ThomasLankenau Institute for Medical Research
Wynnewood, PA

Bibliographic Information

  • Book Title: Rickettsiales

  • Book Subtitle: Biology, Molecular Biology, Epidemiology, and Vaccine Development

  • Editors: Sunil Thomas

  • DOI: https://doi.org/10.1007/978-3-319-46859-4

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing AG 2016

  • Hardcover ISBN: 978-3-319-46857-0Published: 27 December 2016

  • Softcover ISBN: 978-3-319-83603-4Published: 17 July 2018

  • eBook ISBN: 978-3-319-46859-4Published: 20 December 2016

  • Edition Number: 1

  • Number of Pages: XVI, 529

  • Number of Illustrations: 33 b/w illustrations, 81 illustrations in colour

  • Topics: Vaccine, Bacteriology, Infectious Diseases

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