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Resistance to Immunotoxins in Cancer Therapy

  • Book
  • © 2015

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Overview

  • Identifies the mechanisms of resistance in immunotoxin-based therapies for cancer
  • Explores available measures to overcome and prevent resistance in immunotoxin drugs
  • Discusses an array of immune responses in cancer that impact therapeutic strategies

Part of the book series: Resistance to Targeted Anti-Cancer Therapeutics (RTACT, volume 6)

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About this book

This book will be a guide to understanding resistance against targeted therapeutic approaches for cancer using immunotoxins. It contains a detailed review of the history and development of targeted therapy. As well, it includes an in-depth description of the molecular and cellular mechanisms involved in cancer resistance and several novel methods to overcome resistance. Each chapter discusses different aspects of resistance and covers all the factors that may contribute to resistance in cancer cells. Finally, this volume highlights the recent findings and advances associated with tackling cancer resistance.

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Keywords

Table of contents (9 chapters)

Editors and Affiliations

  • Department of Biotechnology, Indian Institute of Technology Madras, Chennai, India

    Rama Shanker Verma

  • Department of Microbiology, Immunology,, University of California of Los Angeles, Los Angeles, USA

    Benjamin Bonavida

About the editors

Rama Shanker Verma, Ph.D., is Professor, Department of Biotechnology, the Indian Institute of Technology. Professor Verma specializes in the development of novel immunotoxins for cancer therapies. He has published 76 scientific articles, five book chapters, and several conference abstracts. He is an Elected Fellow, the Association of Microbiologists of India an Elected Fellow, the Society for Applied Biotechnology. He received the award for Excellence in Medical Biotechnology from the Society for Applied Biotechnology.

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