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Cutaneous Atlas of Ex Vivo Confocal Microscopy

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  • © 2022

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Overview

  • Details the latest advances in the ex vivo confocal microscopy techniques
  • Features a practically applicable step-by-step guide to ex-vivo image acquisition
  • Provides a variety of image types for each condition covered to assist diagnostic skill acquisition

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About this book

This atlas provides a detailed overview of the novel technique of ex vivo confocal microscopy for rapid imaging of excised tissues in dermatological practice. It features an extensive collection of ex vivo images acquired from normal skin structures and from a variety of neoplastic lesions (benign and malignant) and inflammatory lesions. Each chapter contains several image types of a particular disorder, including gray-scale, digital purple-pink images (DHE) and hematoxylin and eosin (H&E) correlations to assist the acquisition of diagnostic skills. Guidance on how to use techniques for tissue preparation, staining, handling and image acquisition are also provided enabling the reader to develop confidence in integrating this technique into their day-to-day practices. Furthermore, this atlas also provides an update on the ongoing latest advances in the field.

 

Cutaneous Atlas of Ex Vivo Confocal Microscopy covers how to apply these techniques into dermatological practice, especially in Mohs surgery for the evaluation of keratinocytic neoplasm and in dermatopathology for rapid evaluation of varied skin lesions. It is therefore a valuable resource for trainee, residents, practicing dermatologists and dermatopathologists who are seeking a resource to assist in developing their knowledge and skills of utilizing these methodologies. 



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Keywords

Table of contents (17 chapters)

  1. Inflammatory Lesions

  2. Future of Ex Vivo Confocal Microscopy

Editors and Affiliations

  • Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center (MSKCC), New York, USA

    Manu Jain, Anthony Rossi, Kishwer Nehal

  • Dermatology Department, Hospital Universitario Virgen del Rocío, Sevilla, Spain

    Mercedes Sendín-Martín

About the editors

Dr. Manu Jain is an Assistant Attending and an optical imaging specialist in the Department of Dermatology at Memorial Sloan Kettering Cancer Center (MSKCC). She has over 10 years of experience working in the field of optical imaging (i.e., in vivo/ex vivo microscopy) that includes technologies such as reflectance confocal microscopy (RCM), fluorescence confocal microscopy (FCM), multiphoton microscopy (MPM), and optical coherence tomography (OCT). At MSKCC, Dr. Jain is leading the clinical, research, and teaching program for RCM in dermatology. She also collaborates with a team of engineers and computational analysts for computer-aided diagnosis of confocal images of skin. She is the Vice President of American Confocal Group and Past-Secretary of the International Tele-Dermatology Society (ITDS). She also created and directs the Annual CME accredited Confocal Course at MSK. Dr. Jain has published many peer-reviewed articles in reputed journals and co-authored several book chapters. She has been an invited speaker at multiple national and international meetings.

Dr. Anthony Rossi is a dermatologist who specializes in Mohs micrographic surgery specialist in the Department of Dermatology at MSKCC. He has significant experience in using reflectance confocal microscopy to help delineate borders of lentigo maligna melanoma and nonmelanoma skin cancers prior to surgery, and is working on research to expand the application of this technology to other aspects of skin cancer management. Dr. Rossi has published numerous journal articles and book chapters and has received presidential service awards from the American Academy of Dermatology, the American Society for Dermatologic Surgery, as well as the American Society for Lasers in Surgery and Medicine.

Dr. Kishwer Nehal the Director of Mohs and Dermatologic Surgery in the Department of Dermatology at MSKCC. She conducts clinical research on noninvasive imaging techniques, such as confocal microscopy and has published the first dedicated book on lentigo maligna melanoma. She works with the National Comprehensive Cancer Network to develop guidelines on managing skin cancers. Besides, she helped the American Joint Committee on Cancer to develop staging criteria for squamous cell carcinomas. She has shared her expertise at national and international meetings and written numerous journal articles and book chapters.

Dr. Mercedes Sendín Martín is a physician in the Department of Dermatology at Hospital Universitario Virgen del Rocío (Seville, Spain), where she works on research related to new optical imaging techniques during her residency program. She is specially focus on confocal imaging research, and published last year an alternative technique for obtaining colored ex vivo confocal images.


Bibliographic Information

  • Book Title: Cutaneous Atlas of Ex Vivo Confocal Microscopy

  • Editors: Manu Jain, Anthony Rossi, Kishwer Nehal, Mercedes Sendín-Martín

  • DOI: https://doi.org/10.1007/978-3-030-89316-3

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022

  • Hardcover ISBN: 978-3-030-89315-6Published: 04 May 2022

  • Softcover ISBN: 978-3-030-89318-7Published: 04 May 2023

  • eBook ISBN: 978-3-030-89316-3Published: 03 May 2022

  • Edition Number: 1

  • Number of Pages: XIV, 178

  • Number of Illustrations: 3 b/w illustrations, 132 illustrations in colour

  • Topics: Dermatology, Pathology, Spectroscopy and Microscopy

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