Overview
- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Neuromethods (NM, volume 131)
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About this book
This volume presents methods for the analysis of genomic variability in vertebrate neurons and broadens our knowledge in the ways we understand the brain and its neurons. The chapters in this book are divided into 5 parts, and cover the following topics: principles and approaches for discovery of somatic mosaicism in the brain, aneuploidy and ploidy variation, DNA copy number variation, LINE-1 retrotransposition, and genetic and genomic mosaicism in aging and disease. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.
Cutting-edge and authoritative, Genomic Mosaicism in Neurons and Other Cell Types is a valuable resource for learning about the latest techniques for the analysis of genome and genetic mosaicism in vertebrate neurons.
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Keywords
Table of contents (17 protocols)
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Introduction
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Aneuploidy and Ploidy Variation
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DNA Copy Number Variation
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LINE-1 Retrotransposition
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Genetic and Genomic Mosaicism in Aging and Disease
Editors and Affiliations
Bibliographic Information
Book Title: Genomic Mosaicism in Neurons and Other Cell Types
Editors: José María Frade, Fred H. Gage
Series Title: Neuromethods
DOI: https://doi.org/10.1007/978-1-4939-7280-7
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media LLC 2017
Hardcover ISBN: 978-1-4939-7279-1Published: 09 September 2017
Softcover ISBN: 978-1-4939-8440-4Published: 18 August 2018
eBook ISBN: 978-1-4939-7280-7Published: 07 September 2017
Series ISSN: 0893-2336
Series E-ISSN: 1940-6045
Edition Number: 1
Number of Pages: XVI, 382
Number of Illustrations: 23 b/w illustrations, 67 illustrations in colour
Topics: Neurosciences