Overview
- First book to discuss the development and validation of LC-MS methods and their applications in analyzing a wide range of drugs
- Will facilitate pharmacologists, toxicologists, and physicians finding relevant analytical techniques in their clinical research
- No other title in the subject area deals with so many methodological chapters
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About this book
Clinical pharmacology plays an important role in today’s medicine. Due to the high sensitivity, selectivity, and affordability of a mass spectrometer (MS), the high performance liquid chromatography – mass spectrometry (LC-MS) analytical technique is widely used in the determination of drugs in human biological matrixes for clinical pharmacology. Specifically, LC-MS is used to analyze: anticancer drugs antidementia drugs antidepressant drugs antiepileptic drugs antifundal drug antimicrobial drugs antipsychotic drugs antiretroviral drugs anxiolytic/hypnotic drugs cardiac drugs drugs for addiction immunosuppressant drugs mood stabilizer drugs This book will primarily cover the various methods of validation for LC-MS techniques and applications used in modern clinical pharmacology.
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Keywords
- Bioanalysis
- LC-MS
- LC-MS/MS
- Liquid chromatography
- MS
- anticancer drugs
- antidementia drugs
- antidepressants
- antiepileptic drugs
- antifundal drugs
- antimicrobial drugs
- antipsychotic drugs
- antiretroviral Drugs
- anxiolytic/hypnotic drugs
- cardiac drugs
- drugs for addiction
- immunosuppressants
- mass spectrometry
- metabolites
- mood stabilizers
Table of contents (14 chapters)
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Front Matter
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Back Matter
Editors and Affiliations
Bibliographic Information
Book Title: LC-MS in Drug Bioanalysis
Editors: Q. Alan Xu, Timothy L. Madden
DOI: https://doi.org/10.1007/978-1-4614-3828-1
Publisher: Springer New York, NY
eBook Packages: Chemistry and Materials Science, Chemistry and Material Science (R0)
Copyright Information: Springer Science+Business Media, LLC 2012
Hardcover ISBN: 978-1-4614-3827-4Published: 16 July 2012
Softcover ISBN: 978-1-4899-9089-1Published: 08 August 2014
eBook ISBN: 978-1-4614-3828-1Published: 15 July 2012
Edition Number: 1
Number of Pages: XII, 472
Topics: Mass Spectrometry, Analytical Chemistry, Pharmacology/Toxicology, Chromatography