Abstract
A series of new (2E,2′E)-1,1′-(4,6-dihydroxy-1,3-phenylene)bis-3-(3-aryl-1-phenyl-1H-pyrazol-4-yl)prop-2-en-1-ones have been synthesized by Claisen-Schmidt condensation of 1-(5-acetyl-2,4-dihydroxyphenyl)-1-ethanone and 3-aryl-1-phenylpyrazole-4-carboxaldehydes under ultrasound and microwave irradiation. These green methods enjoy the advantages of short reaction times, high yields, operational simplicity and are environmentally benign. The synthesized compounds have been characterized by IR, 1H and 13C NMR spectroscopy, mass spectrometry and screened for their antimicrobial activity.
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Ashok, D., Shravani, D., Sarasija, M. et al. Green synthesis of (2E,2′E)-1,1′-(4,6-dihydroxy-1,3-phenylene)bis-3-(3-aryl-1-phenyl-1H-pyrazol-4-yl)-prop-2-en-1-ones. Russ J Gen Chem 85, 752–755 (2015). https://doi.org/10.1134/S1070363215030342
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DOI: https://doi.org/10.1134/S1070363215030342