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Gold carbene chemistry from diazo compounds

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  • Chemistry
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Science Bulletin

Abstract

Diazo compounds are generally used as carbene precursors. Traditionally, dirhodium, copper and iron catalysts were used to decompose diazo compounds to form the key metal carbene intermediates. Recently, the gold catalysts have been developed as a unique type of metal catalyst to decompose diazo compounds. The derived gold carbene showed much different characters comparing with other transition metal carbenes. They could go through a series of cycloaddition, insertion and coupling reactions. Here, the recent progress of the gold carbene chemistry from diazo compounds was reviewed, including the scope of reactions, mechanism and synthetic applications.

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Acknowledgments

This work was supported by the National Natural Science Foundation of China (21372144), China Postdoctoral Science Foundation, the Fundamental Research Funds of Shandong University (2014JC008) and the Subject Construction Funds of Shandong University (104.205.2.5).

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Authors and Affiliations

  1. Key Laboratory for Colloid and Interface Chemistry of Education Ministry, School of Chemistry and Chemical Engineering, Shandong University, Jinan, 250100, China

    Fang Wei, Chuanling Song, Yudao Ma, Chen-Ho Tung & Zhenghu Xu

  2. State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, 200032, China

    Zhenghu Xu

  3. Department of Chemistry and Biochemistry, Miami University, Oxford, OH, 45056, USA

    Ling Zhou

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  1. Fang Wei
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  2. Chuanling Song
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  3. Yudao Ma
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  4. Ling Zhou
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Correspondence to Zhenghu Xu.

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Wei, F., Song, C., Ma, Y. et al. Gold carbene chemistry from diazo compounds. Sci. Bull. 60, 1479–1492 (2015). https://doi.org/10.1007/s11434-015-0874-0

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