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Laparoscopic One Anastomosis Gastric Bypass (OAGB)/Mini Gastric Bypass (MGB): Co-morbidity Outcomes

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Obesity, Bariatric and Metabolic Surgery

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Abstract

One Anastomosis/Mini Gastric Bypass (OAGB-MGB) is an established procedure recognized by the International Federation of Society of Surgeons (IFSO). It is associated with significant improvements in obesity-related comorbidities, including type 2 diabetes mellitus (T2DM), hypertension (HT), obstructive sleep apnea (OSA), and cardiovascular-related disease. In this chapter we will discuss metabolic syndrome, analyze obesity-related comorbidities in more detail, and summarize the reported literature in relation to the outcomes of these comorbidities after OAGB-MGB.

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References

  1. Saklayen MG. The global epidemic of the metabolic syndrome. Curr Hypertens Rep. 2018;20(2):12.

    Article  Google Scholar 

  2. Falcone V, Stopp T, Feichtinger M, Kiss H, Eppel W, Husslein PW, et al. Pregnancy after bariatric surgery: a narrative literature review and discussion of impact on pregnancy management and outcome. BMC Pregnancy Childbirth. 2018;18(1):507. https://doi.org/10.1186/s12884-018-2124-3.

    Article  CAS  Google Scholar 

  3. Purnell JQ, Selzer F, Smith MD, Berk PD, Courcoulas AP, Inabnet WB, et al. Metabolic syndrome prevalence and associations in a bariatric surgery cohort from the Longitudinal Assessment of Bariatric Surgery-2 study. Metab Syndr Relat Disord. 2014;12(2):86–94.

    Article  Google Scholar 

  4. Kramer H, Cao G, Dugas L, Luke A, Cooper R, Durazo-Arvizu R. Increasing BMI and waist circumference and prevalence of obesity among adults with type 2 diabetes: the National Health and Nutrition Examination Surveys. J Diabetes Complicat. 2010;24(6):368–74.

    Article  Google Scholar 

  5. Kashyap SR, Gatmaitan P, Brethauer S, Schauer P. Bariatric surgery for type 2 diabetes: weighing the impact for obese patients. Cleve Clin J Med. 2010;77(7):468–76.

    Article  Google Scholar 

  6. Parmar CD, Mahawar KK. One anastomosis (mini) gastric bypass is now an established bariatric procedure: a systematic review of 12,807 patients. Obes Surg. 2018;28(9):2956–67.

    Article  Google Scholar 

  7. Abu-Abeid A, Lessing Y, Pencovich N, Dayan D, Klausner JM, Abu-Abeid S. Diabetes resolution after one anastomosis gastric bypass. Surg Obes Relat Dis. 2018;14(2):181–5.

    Article  Google Scholar 

  8. Ding L, Fan Y, Li H, et al. Comparative effectiveness of bariatric surgeries in patients with obesity and type 2 diabetes mellitus: a network meta-analysis of randomized controlled trials. Obes Rev. 2020;21(8):e13030.

    Article  CAS  Google Scholar 

  9. Robert M, Espalieu P, Pelascini E, Caiazzo R, Sterkers A, Khamphommala L, et al. Efficacy and safety of one anastomosis gastric bypass versus Roux-en-Y gastric bypass for obesity (YOMEGA): a multicentre, randomised, open-label, non-inferiority trial. Lancet. 2019;393(10178):1299–309.

    Article  Google Scholar 

  10. Wang FG, Yan WM, Yan M, Song MM. Outcomes of Mini vs Roux-en-Y gastric bypass: a meta-analysis and systematic review. Int J Surg. 2018;56:7–14.

    Article  Google Scholar 

  11. Jimenez JM, Carbajo MA, Lopez M, et al. Changes in lipid profile, body weight variables and cardiovascular risk in obese patients undergoing one-anastomosis gastric bypass. Int J Environ Res Public Health. 2020;17(16):5858.

    Article  CAS  Google Scholar 

  12. Jamal W, Zagzoog MM, Sait SH, et al. Initial outcomes of one anastomosis gastric bypass at a single institution. Diabetes Metab Syndr Obes. 2018;12:35–41.

    Article  Google Scholar 

  13. Taha O, Abdelaal M, Abozeid M, et al. Outcomes of omega loopgastric bypass, 6-years’ experience of 1520 cases. Obes Surg. 2017;27:1952–60.

    Article  Google Scholar 

  14. Carbajo MA, Luque-de-León E, Jiménez JM, et al. Laparoscopic one-anastomosis gastric bypass: technique, results, and long-term follow-up in 1200 patients. Obes Surg. 2017;27(5):1153–67.

    Article  Google Scholar 

  15. Seetharamaiah S, Tantia OM, Goyal G, Chaudhuri T, Khanna S, et al. LSG vs OAGB-1 year follow-up data-a randomized control trial. Obes Surg. 2017;27(4):948–54.

    Article  Google Scholar 

  16. Kansou G, Lechaux D, Delarue J, et al. Laparoscopic sleeve gastrectomy versus laparoscopic mini gastric bypass: one year outcomes. Int J Surg. 2016;33:18–22.

    Article  Google Scholar 

  17. Jammu GS, Sharma R. A 7-year clinical audit of 1107 cases comparing sleeve gastrectomy, Roux-en-Y gastric bypass, and mini-gastric bypass, to determine an effective and safe bariatric and metabolic procedure. Obes Surg. 2016;26(5):926–32.

    Article  Google Scholar 

  18. Parmar CD, Mahawar KK, Boyle M, et al. Mini gastric bypass: first report of 125 consecutive cases from United Kingdom. Clin Obes. 2016;6(1):61–7.

    Article  CAS  Google Scholar 

  19. Peraglie C. Laparoscopic mini-gastric bypass in patients age 60 and older. Surg Endosc. 2016;30(1):38–43.

    Article  Google Scholar 

  20. Chevallier JM, Arman GA, Guenzi M, et al. One thousand single anastomosis (omega loop) gastric bypasses to treat morbid obesity in a 7-year period: outcomes show few complications and good efficacy. Obes Surg. 2015;25(6):951–8.

    Article  Google Scholar 

  21. Kular KS, Manchanda N, Rutledge R. A 6-year experience with 1,054 mini-gastric bypasses-first study from Indian subcontinent. Obes Surg. 2014;24(9):1430–5.

    Article  CAS  Google Scholar 

  22. Disse E, Pasquer A, Espalieu P, et al. Greater weight loss with the omega loop bypass compared to the Roux-en-Y gastric bypass: a comparative study. Obes Surg. 2014;24(6):841–6.

    Article  CAS  Google Scholar 

  23. Musella M, Susa A, Greco F, et al. The laparoscopic mini-gastric bypass: the Italian experience: outcomes from 974 consecutive cases in a multicenter review. Surg Endosc. 2014;28(1):156–63.

    Article  CAS  Google Scholar 

  24. Darabi S, Talebpour M, Zeinoddini A, et al. Laparoscopic gastric plication versus mini-gastric bypass surgery in the treatment of morbid obesity: a randomized clinical trial. Surg Obes Relat Dis. 2013;9(6):914–9.

    Article  Google Scholar 

  25. Noun R, Skaff J, Riachi E, et al. One thousand consecutive minigastric bypass: short- and long-term outcome. Obes Surg. 2012;22(5):697–703.

    Article  Google Scholar 

  26. Piazza L, Ferrara F, Leanza S, et al. Laparoscopic mini-gastric bypass: short-term single-institute experience. Updat Surg. 2011;63(4):239–42.

    Article  Google Scholar 

  27. Rutledge R, Walsh TR. Continued excellent results with the mini gastric bypass: six-year study in 2,410 patients. Obes Surg. 2005;15(9):1304–8.

    Article  Google Scholar 

  28. Wang W, Wei P-L, LeeY-C, et al. Short-term results of laparoscopic mini-gastric bypass. Obes Surg. 2005;15(5):648–54.

    Article  Google Scholar 

  29. Ghazaleh RA, Bruzzi M, Bertrand K, M’Harzi L, Zinzindohue F, Douard R, et al. Is mini-gastric bypass a rational approach for type-2 diabetes? Curr Atheroscler Rep. 2017;19(12):51.

    Article  Google Scholar 

  30. Milone M, Di Minno MND, Leongito M, Maietta P, Bianco P, Taffuri C. Bariatric surgery and diabetes remission: sleeve gastrectomy or mini-gastric bypass? World J Gastroenterol. 2013;19(39):6590–7.

    Article  Google Scholar 

  31. Wang FG, Yu ZP, Yan WM, Yan M, Song MM. Comparison of safety and effectiveness between laparoscopic mini-gastric bypass and laparoscopic sleeve gastrectomy: a meta-analysis and systematic review. Medicine (Baltimore). 2017;96(50):e8924.

    Article  Google Scholar 

  32. Dixon JB, Zimmet P, Alberti KG, et al. Bariatric surgery: an IDF statement for obese type 2 diabetes. Surg Obes Relat Dis. 2011;7(4):433–47.

    Article  CAS  Google Scholar 

  33. Climent E, Goday A, Pedro-Botet J, et al. Laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy for 5-year hypertension remission in obese patients: a systematic review and meta-analysis. J Hypertens. 2020;38(2):185–95.

    Article  CAS  Google Scholar 

  34. Owen JG, Yazdi F, Reisin E. Bariatric surgery and hypertension. Am J Hypertens. 2017;31(1):11–7.

    Article  Google Scholar 

  35. Zubaiga L, Abad R, Ruiz-Tovar J, et al. The effects of one-anastomosis gastric bypass on glucose metabolism in Goto-Kakizaki Rats. Obes Surg. 2016;26(11):2622–8.

    Article  Google Scholar 

  36. Wilhelm SM, Young J, Kale-Pradhan PB. Effect of bariatric surgery on hypertension: a meta-analysis. Ann Pharmacother. 2014;48(6):674–82.

    Article  Google Scholar 

  37. Sjostrom L, Lindroos AK, Peltonen M, et al. Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery. N Engl J Med. 2004;351(26):2683–93.

    Article  Google Scholar 

  38. Jirapinyo P, Thompson CC. Treatment of NASH with gastric bypass. Curr Gastroenterol Rep. 2018;20(10):49.

    Article  Google Scholar 

  39. Chalasani N, Younossi Z, Lavine JE, et al. The diagnosis and management of nonalcoholic fatty liver disease: practice guidance from the American Association for the Study of Liver Diseases. Hepatology. 2018;67(1):328–57.

    Article  Google Scholar 

  40. Argo CK, Caldwell SH. Epidemiology and natural history of non-alcoholic steatohepatitis. Clin Liver Dis. 2009;13(4):511–31.

    Article  Google Scholar 

  41. Mummadi RR, Kasturi KS, Chennareddygari S, Sood GK. Effect of bariatric surgery on nonalcoholic fatty liver disease: systematic review and meta-analysis. Clin Gastroenterol Hepatol. 2008;6(12):1396–402.

    Article  Google Scholar 

  42. Kruschitz R, Luger M, Kienbacher C, et al. The effect of Roux-en-Y vs. Omega-loop gastric bypass on liver, metabolic parameters, and weight loss. Obes Surg. 2016;26(9):2204–12.

    Article  Google Scholar 

  43. Peromaa-Haavisto P, Tuomilehto H, Kossi J, et al. Obstructive sleep apnea: the effect of bariatric surgery after 12 months. A prospective multicenter trial. Sleep Med. 2017;35:85–90.

    Article  CAS  Google Scholar 

  44. Pihlajamaki J, Gronlund S, Simonen M, et al. Cholesterol absorption decreases after Roux-en-Y gastric bypass but not after gastric banding. Metabolism. 2010;59(6):866–72.

    Article  Google Scholar 

  45. Dillon CF, Rasch EK, Gu Q, et al. Prevalence of knee osteoarthritis in the United States: arthritis data from the Third National Health and Nutrition Examination Survey 1991–94. J Rheumatol. 2006;33(11):2271–9.

    Google Scholar 

  46. Christensen R, Bartels EM, Astrup A. Effect of weight reduction in obese patients diagnosed with knee osteoarthritis: a systematic review and meta-analysis. Ann Rheum Dis. 2007;66(4):433–9.

    Article  Google Scholar 

  47. Zhao H, Jiao L. Comparative analysis for the effect of Roux-en-Y gastric bypass vs sleeve gastrectomy in patients with morbid obesity: evidence from 11 randomized clinical trials (meta-analysis). Int J Surg. 2019;72:216–23.

    Article  Google Scholar 

  48. Tolone S, Cristiano S, Savarino E. Effects of omega-loop bypass on esophagogastric junction function. Surg Obes Relat Dis. 2016;12(1):62–9.

    Article  Google Scholar 

  49. Tolone S, Savarino E, Bortoli N, et al. Esophageal high-resolution manometry can unravel the mechanisms by which different bariatric techniques produce different reflux exposures. J Gastrointest Surg. 2020;24(1):1–7.

    Article  Google Scholar 

  50. Keleidari B, Mahmoudieh M, Davarpanah J, et al. Comparison of the bile reflux frequency in one anastomosis gastric bypass and Roux-en-Y gastric bypass: a cohort study. Obes Surg. 2019;29:1721–5.

    Article  Google Scholar 

  51. Saarinen T, Rasanen J, Salo J. Bile reflux scintigraphy after mini-gastric bypass. Obes Surg. 2017;27(8):2083–9.

    Article  Google Scholar 

  52. Runkel M, Runkel N. Esophago-gastric cancer after one anastomosis gastric bypass (OAGB). Chirurgia (Bucur). 2019;114(6):686–92.

    Article  Google Scholar 

  53. Aggarwal S, Bhambri A, Singla V, et al. Adenocarcinoma of oesophagus involving gastro-oesophageal junction following mini-gastric bypass/one anastomosis gastric bypass. J Minim Access Surg. 2019;16(2):175–8.

    Article  Google Scholar 

  54. Musella M, Susa A, Manno E. Complications following the mini/one anastomosis gastric Bypass (MGB/OAGB): a multi-institutional survey on 2678 patients with a mid-term (5 years) follow-up. Obes Surg. 2017;27(11):2956–67.

    Article  Google Scholar 

  55. Bruzzi M, Chevallier JM, Czernichow S. One-anastomosis gastric bypass: why biliary reflux remains controversial? Obes Surg. 2017;27(2):545–7.

    Article  Google Scholar 

  56. Pizza F, D’Antonio D, Lucido FS, et al. Postoperative clinical-endoscopic follow-up for GERD and gastritis after one anastomosis gastric bypass for morbid obesity: how, when, and why. Obes Surg. 2020;30(11):4391–400.

    Article  Google Scholar 

  57. Salama TMS, Hassan MI. Incidence of biliary reflux esophagitis after laparoscopic omega loop gastric bypass in morbidly obese patients. J Laparoendosc Adv Surg Tech A. 2017;27(6):618–22.

    Article  Google Scholar 

  58. Parmar CD, Gan J, Stier C, et al. One anastomosis/mini gastric bypass (OAGB-MGB) as revisional bariatric surgery after failed primary adjustable gastric band (LAGB) and sleeve gastrectomy (SG): a systematic review of 1075 patients. Int J Surg. 2020a;81:32–8.

    Article  Google Scholar 

  59. Khrucharoen U, Juo YY, Chen Y, et al. Indications, operative techniques, and outcomes for revisional operation following mini-gastric bypass-one anastomosis gastric bypass: a systematic review. Obes Surg. 2020;30(4):1564–73.

    Article  Google Scholar 

  60. Rajan R, Sam-Aan M, Kosai NR. Early outcome of bariatric surgery for the treatment of type 2 diabetes mellitus in super-obese Malaysian population. J Minim Access Surg. 2020;16(1):47–53.

    Article  Google Scholar 

  61. Parmar CD, Bryant C, Luque-de-Leon E, Peraglie C, Prasad A, Rheinwalt K, et al. One anastomosis gastric bypass in morbidly obese patients with BMI ≥50 kg/m2: a systematic review comparing it with Roux-en-Y gastric bypass and sleeve gastrectomy. Obes Surg. 2019;29(9):3039–46.

    Article  Google Scholar 

  62. Singla V, Aggarwal S, Singh B. Outcomes in super obese patients undergoing one anastomosis gastric bypass or laparoscopic sleeve gastrectomy. Obes Surg. 2019;29(4):1242–7.

    Article  Google Scholar 

  63. Parmar C, Abdelhalim MA, Mahawar KK, Boyle M, Carr WRJ, Jennings N, et al. Management of super-super obese patients: comparison between one anastomosis (mini) gastric bypass and Roux-en-Y gastric bypass. Surg Endosc. 2017;31(9):3504–9.

    Article  Google Scholar 

  64. Parmar CD, Zakeri R, Mahawar K. A systematic review of one anastomosis/mini gastric bypass as a metabolic operation for patients with body mass index ≤35 kg/m2. Obes Surg. 2020b;30(2):725–35.

    Article  Google Scholar 

  65. Garcia- Caballero M, Martínez-Moreno JM, Toval JA, et al. Improvement of C peptide zero BMI 24-34 diabetic patients after tailored one anastomosis gastric bypass (BAGUA). Nutr Hosp. 2013;28(Suppl 2):35–46.

    CAS  Google Scholar 

  66. Kular KS, Manchanda N, Cheema GK. Seven years of mini-gastric bypass in type II diabetes patients with a body mass index <35 kg/m2. Obes Surg. 2016;26(7):1457–62.

    Article  Google Scholar 

  67. Abouzeid TA, Ain Shoka AA, Abd Elsamee Atia KS. From diabetes remedy to diabetes remission; could single-anastomosis gastric bypass be a safe bridge to reach target in non-obese patients? Asian J Surg. 2019;42(1):307–313. https://doi.org/10.1016/j.asjsur.2018.04.002 pii: S1015-9584(18)30049-6

  68. Miller KA, Radauer M, Buchwald JN. 5-year results of banded one-anastomosis gastric bypass: a pilot study in super-obese patients. Obes Surg. 2020;30(11):4307–14.

    Article  Google Scholar 

  69. Sheikh L, Pearless LA, Booth MWC. Laparoscopic silastic ring mini-gastric bypass (SR-MGBP): up to 11-year results from a single centre. Obes Surg. 2017;27(9):2229–34.

    Article  Google Scholar 

  70. Salvi P, Kosta S, Fobi M, et al. Banded sleeve gastrectomy and one anastomosis gastric bypass/mini-gastric bypass for treatment of obesity: a retrospective cohort comparative study with 6 years follow-up. Obes Surg. 2020;30(4):1303–9.

    Article  Google Scholar 

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Authors and Affiliations

  1. Department of General and Bariatric Surgery, Whittington Hospital NHS Trust, London, UK

    Chetan Parmar

  2. University College London, London, UK

    Chetan Parmar

  3. Department of Surgery, Whittington Hospital NHS Trust, London, UK

    Simon J. McCluney

Authors
  1. Chetan Parmar
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  2. Simon J. McCluney
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Correspondence to Chetan Parmar .

Editor information

Editors and Affiliations

  1. Homerton University Hospital, London, UK

    Sanjay Agrawal

Section Editor information

  1. Department of Surgery, Sunderland Royal Hospital, Sunderland, UK

    Kamal Mahawar MS, MSc, FRCSEd

  2. Department of General and Bariatric Surgery, Whittington Hospital, London, UK

    Chetan Parmar

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Parmar, C., McCluney, S.J. (2023). Laparoscopic One Anastomosis Gastric Bypass (OAGB)/Mini Gastric Bypass (MGB): Co-morbidity Outcomes. In: Agrawal, S. (eds) Obesity, Bariatric and Metabolic Surgery. Springer, Cham. https://doi.org/10.1007/978-3-030-60596-4_93

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  • DOI: https://doi.org/10.1007/978-3-030-60596-4_93

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-60595-7

  • Online ISBN: 978-3-030-60596-4

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