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Pharmacologic Management of Reproductive Psychopathology

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Tasman’s Psychiatry

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Abstract

The pharmacological management of psychopathology among women, specifically during their reproductive years, is highly complex and requires specialized knowledge regarding medication efficacy and safety. In this chapter, the reader is introduced to the complex guidelines for treating women in the peripartum period with psychotropic medicines, elaborating on common mental disorders including depression, bipolar illness, anxiety, posttraumatic stress and other trauma-related conditions, ADHD, and substance use disorders. It is highlighted that mental illness during the peripartum, that is, pregnancy and the first year after the infant’s birth, is highly prevalent. While the pharmacological management of mental health conditions during the peripartum is often comparable to treating such conditions at any other period in a woman’s life, decisions regarding medication selection require not only consideration of side effects for the mother but must also consider potential adverse effects on the pregnancy, the fetus, delivery, and long-term child development. Thus, critical to reproductive psychiatry is a personalized risk-benefit analysis accounting for a broad range of considerations. In this text the aim is to provide the reader with the foundational knowledge needed to support the patient and family in this complex decision-making process. Treatment algorithms for the pharmacologic management of premenstrual and perimenopausal mental health disorders are also presented. The overall goal of this chapter is to offer comprehensive, yet user-friendly, state-of-the-art information on medication management in reproductive psychiatry.

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Author information

Authors and Affiliations

  1. Departments of Psychiatry, Obstetrics & Gynecology, University of Michigan- Michigan Medicine, Ann Arbor, MI, USA

    Maria Muzik

  2. Zero To Thrive & Women and Infant Mental Health Program, Ann Arbor, MI, USA

    Maria Muzik

  3. Perinatal Psychiatry Service, Ann Arbor, MI, USA

    Maria Muzik

  4. MC3 Perinatal Psychiatry Assess Program Michigan, Ann Arbor, MI, USA

    Maria Muzik

  5. Department of Psychiatry, Rachel Upjohn Building, Ann Arbor, MI, USA

    Samantha Shaw

  6. Department of Psychiatry, University of Michigan- Michigan Medicine, Ann Arbor, MI, USA

    Samantha Shaw

  7. University of Toronto, Toronto, ON, Canada

    Sophie Grigoriadis

  8. Women’s Mood and Anxiety Clinic: Reproductive Transitions, Toronto, ON, Canada

    Sophie Grigoriadis

  9. Department of Psychiatry, Sunnybrook Health Sciences Centre, Toronto, ON, Canada

    Sophie Grigoriadis

  10. Sunnybrook Research Institute, Toronto, ON, Canada

    Sophie Grigoriadis

  11. Women’s College Research Institute, Toronto, ON, Canada

    Sophie Grigoriadis

  12. Psychiatry and Obstetrics & Gynecology, Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA

    Kristina M. Deligiannidis

  13. Feinstein Institutes for Medical Research, Manhasset, NY, USA

    Kristina M. Deligiannidis

  14. Katz Institute for Women’s Health, Queens, NY, USA

    Kristina M. Deligiannidis

  15. Psychiatry, University of Massachusetts Medical School, Worcester, MA, USA

    Kristina M. Deligiannidis

  16. Women’s Behavioral Health, Zucker Hillside Hospital, Northwell Health, Glen Oaks, NY, USA

    Kristina M. Deligiannidis

  17. Greater Manchester Mental Health NHS Foundation Trust & University of Manchester, Manchester, UK

    Angelika Wieck

  18. Laureate House, Manchester, UK

    Angelika Wieck

  19. Wythenshawe Hospital, Manchester, UK

    Angelika Wieck

  20. Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India

    Prabha S. Chandra

  21. International Association for Women’s Mental Health, Bangalore, India

    Prabha S. Chandra

  22. Women’s Mental Health, Bangalore, India

    Manisha Murugesan

  23. Department of Psychiatry, NIMHANS, Bangalore, India

    Manisha Murugesan

  24. Department of Obstetrics, Gynecology and Reproductive Biology, College of Human Medicine, Michigan State University, East Lansing, MI, USA

    Cara Anne Poland

  25. Nurse Midwife, Grand Rapids, MI, USA

    Nancy Renn-Bugai

  26. Corewell Health, Grand Rapids, MI, USA

    Nancy Renn-Bugai

Authors
  1. Maria Muzik
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  2. Samantha Shaw
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  3. Sophie Grigoriadis
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  4. Kristina M. Deligiannidis
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  5. Angelika Wieck
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  6. Prabha S. Chandra
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  7. Manisha Murugesan
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  8. Cara Anne Poland
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  9. Nancy Renn-Bugai
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Corresponding author

Correspondence to Maria Muzik .

Editor information

Editors and Affiliations

  1. Department of Psychiatry, University of Louisville, Louisville, KY, USA

    Allan Tasman

  2. Department of Psychiatry, University of Michigan Rogel Cancer Cent, Ann Arbor, MI, USA

    Michelle B. Riba

  3. Mayo Clinic College of Medicine, Oakland, CA, USA

    Renato D. Alarcón

  4. Columbia University Medical Center, New York, USA

    César A. Alfonso

  5. Kyushu University, Fukuoka, Japan

    Shigenobu Kanba

  6. Department of Psychiatry, University of Nairobi, Nairobi, Kenya

    David M. Ndetei

  7. Malaysian Research Inst on Ageing, Universiti Putra Malaysia, Selangor, Malaysia

    Chee H. Ng

  8. Department of Psychiatry, University of Munich, München, Bayern, Germany

    Thomas G. Schulze

  9. Serbian Academy of Sciences and Arts, Belgrade, Serbia

    Dusica Lecic-Tosevski

Section Editor information

  1. No affiliation provided

    Shigenobu Kanba

  2. No affiliation provided

    Rif S. El-Mallakh

  3. No affiliation provided

    Joseph Zohar

  4. No affiliation provided

    Andrew D. Krystal

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Muzik, M. et al. (2023). Pharmacologic Management of Reproductive Psychopathology. In: Tasman, A., et al. Tasman’s Psychiatry. Springer, Cham. https://doi.org/10.1007/978-3-030-42825-9_143-1

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