Abstract
Osteoporosis is a major health concern worldwide and within the United States. Approximately 9 % of U.S. adults over the age of 50 have osteoporosis, and up to 50 % have some degree of low bone density [1]. Osteoporosis causes more than two million fractures per year with $19 billion in associated costs in the United States alone [2]. The clinical costs of an osteoporotic fracture are equally great and include increased mortality, increased disability, and an increased need for long-term nursing care. The most common sites of fracture are the hip, vertebrae, and wrist. Hip fractures are particularly deadly, carrying a 26 % 1-year mortality rate for patients over the age of 69. Of those who survive, functional skills are significantly decreased with decreased fine motor and mobility scores [3]. Vertebral fractures lead to chronic back pain and deformity in up to 30 % of patients. These fractures may have a long-term impact on overall quality of life and the ability to carry out activities of daily living (ADL).
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References
Looker AC, Borrud LG, Dawson-Hughes B, Shepherd JA, Wright NC. Osteoporosis or low bone mass at the femur neck or lumbar spine in older adults: United States, 2005–2008. NCHS Data Brief. 2012; 93:1–8.
National Osteoporosis Foundation. What is osteoporosis? http://www.nof.org/osteoporosis/articles/7. Accessed 19 Feb 2014.
Bentler SE, Liu L, Obrizan M, Cook EA, Wright KB, Geweke JF, Chrischilles EA, Pavlik CE, Wallace RB, Ohsfeldt RL, Jones MP, Rosenthal GE, Wolinsky FD. The aftermath of hip fracture: discharge placement, functional status change, and mortality. Am J Epidemiol. 2009;170(10):1290.
Hiligsmann M, Bruyère O, Ethgen O, Gathon HJ, Reginster JY. Lifetime absolute risk of hip and other osteoporotic fracture in Belgian women. Bone. 2008;43(6):991–4.
Diab DL, Watts NB. Secondary osteoporosis: differential diagnosis and workup. Clin Obstet Gynecol. 2002;288(18):2300.
The NIH Osteoporosis and Related Bone Diseases~National Resource Center. Smoking and bone health. http://www.niams.nih.gov/Health_Info/Bone/Osteoporosis/Conditions_Behaviors/bone_smoking.asp. Accessed 19 Feb 2015.
Wang PS, Solomon DH, Mogun H, Avorn J. HMG-CoA reductase inhibitors and the risk of hip fractures in elderly patients. JAMA. 2000;283:3211.
Feskanich D, Willett W, Colditz G. Walking and leisure-time activity and risk of hip fracture in postmenopausal women. JAMA. 2002;288(18):2300.
Diab DL, Watts NB. Secondary osteoporosis: differential diagnosis and workup. Clin Obstet Gynecol. 2013;56(4):686–93.
The International Society for Densitometry. 2013 ISCD official positions – adult. Middletown: The International Society for Densitometry. http://www.iscd.org/official-positions/2013-iscd-official-positions-adult/. Accessed 3 Jan 2015.
Kanis JA, on behalf of the World Health Organization Scientific Group. Assessment of osteoporosis at the primary health-care level. Technical report. World Health Organization Collaborating Centre for Metabolic Bone Diseases, University of Sheffield. http://www.shef.ac.uk/FRAX/pdfs/WHO_Technical_Report.pdf. Accessed 22 Dec 2014.
WHO Fracture Risk Assessment Tool (FRAX). http://www.shef.ac.uk/FRAX. Accessed 23 Dec 2014.
New recommended daily amounts of Calcium and Vitamin D. NIH Medline Plus. Winter 2011; 5(4): 12. http://www.nlm.nih.gov/medlineplus/magazine/issues/winter11/articles/winter11pg12.html. Accessed 19 Feb 2015.
Jackson RD, LaCroix AZ, Gass M, Wallace RB, Robbins J, Lewis CE, et al. Calcium plus vitamin D supplementation and the risk of fractures. N Engl J Med. 2006;354(7):669.
National Osteoporosis Foundation. Calcium and Vitamin D: what you need to know. http://nof.org/articles/10#howmuchvitamind. Accessed 23 Dec 2014.
Howe TE, Shea B, Dawson LJ, Downie F, Murray A, Ross C, et al. Exercise for preventing and treating osteoporosis in postmenopausal women. Cochrane Database Syst Rev. 2011; 7(CD000333).
Rossouw JE, Anderson GL, Prentice RL, et al. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principle results from the Women’s Health Initiative randomized controlled trial. JAMA. 2002;288(3):321–33.
Eng-Wong J, Reynolds JC, Venzon D, Liewehr D, Gantz S, Danforth D, et al. Effect of raloxifene on bone mineral density in premenopausal women at increased risk of breast cancer. J Clin Endocrinol Metab. 2006;91(10):3941.
Knopp-Sihota JA, Newburn-Cook CV, Homik J, Cummings GG, Voaklander D. 1- Calcitonin for treating acute and chronic pain of recent and remote osteoporotic vertebral compression fractures: a systematic review and meta-analysis. Osteoporos Int. 2012;23(1):17.
Downs Jr RW, Bell NH, Ettinger MP, Walsh BW, Favus MJ, Mako B, Wang L, Smith ME, Gormley GJ, Melton ME. Comparison of alendronate and intranasal calcitonin for treatment of osteoporosis in postmenopausal women. J Clin Endocrinol Metab. 2000;85(5):1783.
Vahle JL, Sato M, Long GG, et al. Skeletal changes in rats given daily subcutaneous injections of recombinant human parathyroid hormone (1–34) for 2 years and relevance to human safety. Toxicol Pathol. 2002;30(3):312.
Cummings SR, San Martin J, McClung MR, et al. Denosumab for prevention of fractures in postmenopausal women with osteoporosis. N Engl J Med. 2009;361(8):756–65.
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Reeve, K., West, R. (2015). Osteopenia and Osteoporosis. In: Paulman, P., Taylor, R. (eds) Family Medicine. Springer, Cham. https://doi.org/10.1007/978-1-4939-0779-3_129-1
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DOI: https://doi.org/10.1007/978-1-4939-0779-3_129-1
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Osteopenia and Osteoporosis- Published:
- 12 December 2020
DOI: https://doi.org/10.1007/978-1-4939-0779-3_129-2
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Osteopenia and Osteoporosis- Published:
- 28 September 2015
DOI: https://doi.org/10.1007/978-1-4939-0779-3_129-1