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Supercritical Fluid Extraction in Natural Products Analyses

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Natural Products Isolation

Part of the book series: Methods in Molecular Biology ((MIMB,volume 864))

Abstract

Supercritical fluids (SCFs) are increasingly replacing the organic solvents, e.g., n-hexane, chloroform, dichloromethane, or methanol, that are conventionally used in industrial extraction, purification, and recrystallization operations because of regulatory and environmental pressures on hydrocarbon and ozone-depleting emissions. In natural products extraction and isolation, supercritical fluid extraction (SFE), especially employing supercritical CO2, has become a popular choice. Sophisticated modern technologies allow precise regulation of changes in temperature and pressure, and thus manipulation of solvating property of the SCF, which helps the extraction of natural products of a wide range of polarities. This chapter deals mainly with the application of the SFE technology in the natural products extraction and isolation, and outlines various methodologies with specific examples.

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Authors and Affiliations

  1. Leicester School of Pharmacy, De Montfort University, The Gateway, Leicester, UK

    Lutfun Nahar

  2. Department of Pharmacy, School of Applied Sciences, University of Wolverhampton, Wolverhampton, WV11LY, UK

    Satyajit D. Sarker

Authors
  1. Lutfun Nahar
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  2. Satyajit D. Sarker
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Correspondence to Lutfun Nahar .

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Editors and Affiliations

  1. School of Applied Sciences, Department of Pharmacy, University of Wolverhampton, Wulfruna Street, Wolverhampton, WV1 1LY, United Kingdom

    Satyajit D. Sarker

  2. , Leicester School of Pharmacy, De Montfort University, The Gateway, Leicester, LE1 9BH, United Kingdom

    Lutfun Nahar

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Nahar, L., Sarker, S.D. (2012). Supercritical Fluid Extraction in Natural Products Analyses. In: Sarker, S., Nahar, L. (eds) Natural Products Isolation. Methods in Molecular Biology, vol 864. Humana Press. https://doi.org/10.1007/978-1-61779-624-1_3

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  • DOI: https://doi.org/10.1007/978-1-61779-624-1_3

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  • Publisher Name: Humana Press

  • Print ISBN: 978-1-61779-623-4

  • Online ISBN: 978-1-61779-624-1

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