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Fast Atom Bombardment and Secondary Ion Mass Spectrometry of Peptides and Proteins

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Methods of Protein Microcharacterization

Part of the book series: Biological Methods ((BM))

Abstract

Traditionally, mass spectrometric analysis was a gas-phase process that was limited to relatively low molecular weight compounds having enough volatility and thermal stability to permit vaporization. Application of the technique to peptides required extensive chemical degradation and derivatization. Despite these limitations, mass spectrometry has made a significant contribution, as can be seen from chapter 15 in this volume.

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  1. Beckman Research Institute of the City of Hope, Duarte, California

    Terry D. Lee

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  1. Beckman Research Institute of the City of Hope, Duarte, California

    John E. Shively

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Lee, T.D. (1986). Fast Atom Bombardment and Secondary Ion Mass Spectrometry of Peptides and Proteins. In: Shively, J.E. (eds) Methods of Protein Microcharacterization. Biological Methods. Humana Press. https://doi.org/10.1007/978-1-59259-436-8_16

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  • DOI: https://doi.org/10.1007/978-1-59259-436-8_16

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-090-9

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