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Detection of α-Synuclein in Biological Samples Using Mass Spectrometry

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Alpha-Synuclein

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1948))

Abstract

Here we describe a method using mass spectrometry to characterize and quantify immuno-enriched α-synuclein forms from biochemically fractionated brain tissue.

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Acknowledgments

Work in the authors’ laboratories is supported by the Michael J. Fox Foundation (MJFF) for Parkinson’s Research, the Swedish Research Council, the European Research Council, the Knut and Alice Wallenberg Foundation, the Torsten Söderberg Foundation, the Eivind and Elsa K:Son Sylvans Foundation, the Märtha and Gustaf Ågrens Foundation, the Olav Thon Foundation, Swedish State Support for Clinical Research (ALFGBG), Alzheimerfonden, Stiftelsen för Gamla Tjänarinnor, and Frimurarestiftelsen.

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Correspondence to Henrik Zetterberg .

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Brinkmalm, A., Öhrfelt, A., Bhattacharjee, P., Zetterberg, H. (2019). Detection of α-Synuclein in Biological Samples Using Mass Spectrometry. In: Bartels, T. (eds) Alpha-Synuclein. Methods in Molecular Biology, vol 1948. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-9124-2_16

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  • DOI: https://doi.org/10.1007/978-1-4939-9124-2_16

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-9123-5

  • Online ISBN: 978-1-4939-9124-2

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