Abstract
Cholesterol has long been implicated in diverse aspects of human health and disease. As this lipid is both vital and lethal, ensuring that its levels are kept in check is important for maintaining health. However, studying cholesterol homeostasis can be challenging due to the extreme hydrophobic nature of cholesterol and the membranous world it inhabits. This volume of Methods in Molecular Biology brings together 21 techniques covering the gamut of cholesterol homeostasis.
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References
Brown MS, Goldstein JL (1985) A receptor-mediated pathway for cholesterol homeostasis. Nobel Lectures:284–324
Howe V, Sharpe LJ, Alexopoulos SJ, Kunze SV, Chua NK, Li D, Brown AJ (2016) Cholesterol homeostasis: how do cells sense sterol excess? Chem Phys Lipids 199:170–178
Du X, Brown AJ, Yang H (2015) Novel mechanisms of intracellular cholesterol transport: oxysterol-binding proteins and membrane contact sites. Curr Opin Lipidol 35:37–42
Chu BB, Liao YC, Qi W, Xie C, Du X, Wang J, Yang H, Miao HH, Li BL, Song BL (2015) Cholesterol transport through lysosome-peroxisome membrane contacts. Cell 161(2):291–306
Brown AJ, Sharpe LJ (2015) Cholesterol synthesis. In: Biochemistry of lipids, lipoproteins, and membranes, 6th edn. Elsevier, The Netherlands.
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Gelissen, I.C., Brown, A.J. (2017). An Overview of Cholesterol Homeostasis. In: Gelissen, I., Brown, A. (eds) Cholesterol Homeostasis. Methods in Molecular Biology, vol 1583. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-6875-6_1
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DOI: https://doi.org/10.1007/978-1-4939-6875-6_1
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