Abstract
Superparamagnetic iron oxide (SPIO) nanoparticles can function as specific, long-term multimodal contrast agents for noninvasive imaging studies. Here we describe how to achieve high-resolution, long-term, serial images of single-label transplanted cells through two complementary imaging techniques: magnetic resonance imaging (MRI) and microcomputed tomography (μCT).
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Acknowledgements
We would like to acknowledge the following investigators who were all involved in the original development and assessment of this methodology: Peter E. Hammer, Allison A. MacKay, Rory P. Dowd, Kai-Roy Wang, Akihiro Masuzawa, Bjoern Sill, James D. McCully, and Douglas B. Cowan.
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Sriramvenugopal, M., Pacak, C.A. (2020). Noninvasive Tracking of Implanted Cells: Superparamagnetic Iron Oxide Nanoparticles as a Long-Term, Multimodal Imaging Label. In: Basel, M., Bossmann, S. (eds) Cell Tracking. Methods in Molecular Biology, vol 2126. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-0364-2_15
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DOI: https://doi.org/10.1007/978-1-0716-0364-2_15
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