Computational Pharmacokinetics

In this topical collection (9 articles)

1. Commentary

   Drug-target and disease networks: polypharmacology in the post-genomic era

   Ali Masoudi-Nejad, Zaynab Mousavian, Joseph H Bozorgmehr Article:17

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2. Original research

   Quantitative In Silico analysis of transient metabolism of acetaminophen and associated causes of hepatotoxicity in humans

   Ali Navid, David M Ng, Benjamin J Stewart, Sergio E Wong… Article:14

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3. Original research

   In silico drug metabolism and pharmacokinetic profiles of natural products from medicinal plants in the Congo basin

   Fidele Ntie-Kang, Lydia L Lifongo, James A Mbah… Article:12

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4. Original research

   A framework incorporating the impact of exposure scenarios and application conditions on risk assessment of chemicals applied to skin

   Yuri Dancik, John A Troutman, Joanna Jaworska Article:10

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5. Original research

   The Simcyp Population Based Simulator: Architecture, Implementation, and Quality Assurance

   Masoud Jamei, Steve Marciniak, Duncan Edwards, Kris Wragg… Article:9

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6. Review

   Modeling bioavailability to organs protected by biological barriers

   Nadia Quignot Article:8

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7. Editorial

   Computational pharmacokinetics at a crossroads

   Frédéric Y Bois Article:5

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8. Original research

   Use of a physiologically-based pharmacokinetic model to simulate artemether dose adjustment for overcoming the drug-drug interaction with efavirenz

   Marco Siccardi, Adeniyi Olagunju, Kay Seden, Farid Ebrahimjee… Article:4

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9. Original research

   In silico evaluation of gadofosveset pharmacokinetics in different population groups using the Simcyp® simulator platform

   Marios Spanakis, Kostas Marias Article:2

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