2021 Zuckerkandl Prize David A. LiberlesMichelle M. MeyerAshley I. Teufel ANNOUNCEMENT 17 December 2021 Pages: 1 - 1
Rapid Divergence of Key Spermatogenesis Genes in nasuta-Subgroup of Drosophila Rajanikanth ChowdanayakaRamachandra Nallur Basappa Original Article 22 November 2021 Pages: 2 - 16
Context-Dependent Mutation Dynamics, Not Selection, Explains the Codon Usage Bias of Most Angiosperm Chloroplast Genes Brian R. Morton Original Article Open access 21 December 2021 Pages: 17 - 29
Evolution of the N-Terminal Regulation of Cardiac Troponin I for Heart Function of Tetrapods: Lungfish Presents an Example of the Emergence of Novel Submolecular Structure to Lead the Capacity of Adaptation Monica RasmussenHan-Zhong FengJ.-P. Jin Original Article 29 December 2021 Pages: 30 - 43
Context-Dependent Substitution Dynamics in Plastid DNA Across a Wide Range of Taxonomic Groups Brian R. Morton Original Article 17 January 2022 Pages: 44 - 55
Evolution of DNA Methylation Across Ecdysozoa Jan EngelhardtOliver ScheerSonja J. Prohaska Original Article Open access 28 January 2022 Pages: 56 - 72
Amino Acid Specificity of Ancestral Aminoacyl-tRNA Synthetase Prior to the Last Universal Common Ancestor Commonote commonote Ryutaro FurukawaShin-ichi YokoboriAkihiko Yamagishi Original Article Open access 27 January 2022 Pages: 73 - 94
The Ancient Origins of Death Domains Support the ‘Original Sin’ Hypothesis for the Evolution of Programmed Cell Death So Ri LaAndrew NdhlovuPierre M. Durand Original Article 27 January 2022 Pages: 95 - 113
Stem Region of tRNA Genes Favors Transition Substitution Towards Keto Bases in Bacteria Piyali SenRuksana AzizSiddhartha Sankar Satapathy Original Article 27 January 2022 Pages: 114 - 123
Promiscuous Domains in Eukaryotes and HAT Proteins in FUNGI Have Followed Different Evolutionary Paths Jazmín Murcia-GarzónAlfonso Méndez-Tenorio Original Article 27 January 2022 Pages: 124 - 138
Cost-Efficiency Optimization Serves as a Conserved Mechanism that Promotes Osteosarcoma in Mammals Haibin WangGuoyong SunYankai Jiang Original Article 21 January 2022 Pages: 139 - 148