Genomics of cancer progression and heterogeneity

In this topical collection (41 articles)

Page is not a valid page number. Please enter a number between 1 and 3 of 3

1. Research

   Deep sequencing of multiple regions of glial tumors reveals spatial heterogeneity for mutations in clinically relevant genes

   Akash Kumar, Evan A Boyle, Mari Tokita, Andrei M Mikheev… Article:530

   Download PDF (1185KB) View Article

2. Research

   Characterizing heterogeneity in leukemic cells using single-cell gene expression analysis

   Assieh Saadatpour, Guoji Guo, Stuart H Orkin, Guo-Cheng Yuan Article:525

   Download PDF (4284KB) View Article

3. Method

   MSEA: detection and quantification of mutation hotspots through mutation set enrichment analysis

   Peilin Jia, Quan Wang, Qingxia Chen, Katherine E Hutchinson, William Pao… Article:489

   Download PDF (1425KB) View Article

4. Method

   A general framework for analyzing tumor subclonality using SNP array and DNA sequencing data

   Bo Li, Jun Z Li Article:473

   Download PDF (2423KB) View Article

5. Method

   Dynamic evolution of clonal epialleles revealed by methclone

   Sheng Li, Francine Garrett-Bakelman, Alexander E Perl, Selina M Luger… Article:472

   Download PDF (1382KB) View Article

6. Research

   Spatial and temporal evolution of distal 10q deletion, a prognostically unfavorable event in diffuse low-grade gliomas

   Hinke F van Thuijl, Ilari Scheinin, Daoud Sie, Agusti Alentorn… Article:471

   Download PDF (1572KB) View Article

7. Method

   Deciphering clonality in aneuploid breast tumors using SNP array and sequencing data

   Ingrid M Lönnstedt, Franco Caramia, Jason Li, Debora Fumagalli… Article:470

   Download PDF (5007KB) View Article

8. Editorial

   Cancer genomics just got personal

   Rafal T Marszalek Article:464

   Download PDF (204KB) View Article

9. Editorial

   Tumor heterogeneity: next-generation sequencing enhances the view from the pathologist's microscope

   Samuel Aparicio, Elaine Mardis Article:463

   Download PDF (196KB) View Article

10. Opinion

    Toward better benchmarking: challenge-based methods assessment in cancer genomics

    Paul C Boutros, Adam A Margolin, Joshua M Stuart, Andrea Califano… Article:462

    Download PDF (567KB) View Article

11. Review

    Individualizing kinase-targeted cancer therapy: the paradigm of chronic myeloid leukemia

    Anna M Eiring, Michael W Deininger Article:461

    Download PDF (1119KB) View Article

12. Research

    Comparative sequencing analysis reveals high genomic concordance between matched primary and metastatic colorectal cancer lesions

    A Rose Brannon, Efsevia Vakiani, Brooke E Sylvester, Sasinya N Scott… Article:454

    Download PDF (1154KB) View Article

13. Review

    Deciphering intratumor heterogeneity and temporal acquisition of driver events to refine precision medicine

    Crispin Hiley, Elza C de Bruin, Nicholas McGranahan, Charles Swanton Article:453

    Download PDF (516KB) View Article

14. Review

    Cancer genomics: one cell at a time

    Nicholas E Navin Article:452

    Download PDF (640KB) View Article

15. Review

    Genotyping cell-free tumor DNA in the blood to detect residual disease and drug resistance

    Giulia Siravegna, Alberto Bardelli Article:449

    Download PDF (514KB) View Article

16. Review

    The promise of circulating tumor cell analysis in cancer management

    Joaquin Mateo, Marco Gerlinger, Daniel Nava Rodrigues, Johann S de Bono Article:448

    Download PDF (822KB) View Article

17. Opinion

    The multitude of molecular analyses in cancer: the opening of Pandora’s box

    Hege G Russnes, Per E Lønning, Anne-Lise Børresen-Dale, Ole C Lingjærde Article:447

    Download PDF (483KB) View Article

18. Review

    MicroRNA regulation of tumorigenesis, cancer progression and interpatient heterogeneity: towards clinical use

    S Patrick Nana-Sinkam, Carlo M Croce Article:445

    Download PDF (394KB) View Article

19. Research highlight

    One patient, two lesions, two oncogenic drivers of gastric cancer

    Clara Alsinet, Marco Ranzani, David J Adams Article:444

    Download PDF (311KB) View Article

20. Method

    SubcloneSeeker: a computational framework for reconstructing tumor clone structure for cancer variant interpretation and prioritization

    Yi Qiao, Aaron R Quinlan, Amir A Jazaeri, Roeland GW Verhaak… Article:443

    Download PDF (1569KB) View Article

Page is not a valid page number. Please enter a number between 1 and 3 of 3