Generalisation of Genomic Findings and Applications of Polygenic Risk Scores (MGNM) GGFAPRS

In this topical collection (9 articles)

1. Research

   Novel pathogenic variant in MED12 causing non-syndromic dilated cardiomyopathy

   Serwa Ghasemi, Mohammad Mahdavi, Majid Maleki, Iman Salahshourifar… Article:334

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2. Research

   Polygenic risk for triglyceride levels in the presence of a high impact rare variant

   Shengjie Ying, Tracy Heung, Bhooma Thiruvahindrapuram… Article:281

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3. Research

   The association between basal metabolic rate and osteoarthritis: a Mendelian randomization study

   Jingyu Zhou, Peng Wei, Feng Yi, Shilang Xiong, Min Liu, Hanrui Xi… Article:258

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4. Editorial

   Generalisation of genomic findings and applications of polygenic risk scores

   Manuel Corpas, Segun Fatumo Article:175

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5. Research

   Assessing the performance of European-derived cardiometabolic polygenic risk scores in South-Asians and their interplay with family history

   Emadeldin Hassanin, Carlo Maj, Hannah Klinkhammer, Peter Krawitz… Article:164

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6. Research

   Generalizability of polygenic prediction models: how is the R² defined on test data?

   Christian Staerk, Hannah Klinkhammer, Tobias Wistuba, Carlo Maj… Article:132

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7. Research

   Identification of diagnostic model in heart failure with myocardial fibrosis and conduction block by integrated gene co-expression network analysis

   Yonghua Yuan, Yiwei Niu, Jiajun Ye, Yuejuan Xu, Xuehua He, Sun Chen Article:52

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8. Research

   MPZL2—a common autosomal recessive deafness gene related to moderate sensorineural hearing loss in the Chinese population

   Lang Zhang, Jin-Yuan Yang, Qiu-Quan Wang, Xue Gao, Guo-Jian Wang… Article:32

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9. Comment

   A brief comparison of polygenic risk scores and Mendelian randomisation

   Victoria Garfield, Emma L. Anderson Article:10

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