Biosimilarity Versus Manufacturing Change: Two Distinct Concepts Paul DeclerckMourad Farouk-RezkPauline M. Rudd Expert Review 17 September 2015 Pages: 261 - 268
Increased Plasma Concentrations of Unbound SN-38, the Active Metabolite of Irinotecan, in Cancer Patients with Severe Renal Failure Ken-ichi FujitaYusuke MasuoYukio Kato Research Paper 03 September 2015 Pages: 269 - 282
Applicability of Bipolar Charge Analyzer (BOLAR) in Characterizing the Bipolar Electrostatic Charge Profile of Commercial Metered Dose Inhalers (MDIs) Sharon Shui Yee LeungAdam Chong Ming ChiowHak-Kim Chan Research Paper 03 September 2015 Pages: 283 - 291
Physiologically-Based Pharmacokinetic and Pharmacodynamic Modeling for the Inhibition of Acetylcholinesterase by Acotiamide, A Novel Gastroprokinetic Agent for the Treatment of Functional Dyspepsia, in Rat Stomach Kazuyoshi YoshiiMinami IikuraYoshihiro Kawabata Research Paper Open access 09 September 2015 Pages: 292 - 300
Oxaprozin-Loaded Lipid Nanoparticles towards Overcoming NSAIDs Side-Effects José Lopes-de-AraújoAna Rute NevesSalette Reis Research Paper 09 September 2015 Pages: 301 - 314
Curcumin Nanoparticles Attenuate Production of Pro-inflammatory Markers in Lipopolysaccharide-Induced Macrophages Wing-Hin LeeChing-Yee LooDaniela Traini Research Paper 09 September 2015 Pages: 315 - 327
Pharmacokinetic Properties of a Novel d-Peptide Developed to be Therapeutically Active Against Toxic β-Amyloid Oligomers Leonie H. E. LeitholdNan JiangDieter Willbold Research Paper 17 September 2015 Pages: 328 - 336
Thermodynamic Changes Induced by Intermolecular Interaction Between Ibuprofen and Chitosan: Effect on Crystal Habit, Solubility and In Vitro Release Kinetics of Ibuprofen Amos Olusegun AbioyeRachel ArmitageAdeola Tawakalitu Kola-Mustapha Research Paper 24 September 2015 Pages: 337 - 357
Temperature/pH Responsive Hydrogels Based on Poly(ethylene glycol) and Functionalized Poly(e-caprolactone) Block Copolymers for Controlled Delivery of Macromolecules Nazila Safaei NikoueiNasim GhasemiAfsaneh Lavasanifar Research Paper 28 September 2015 Pages: 358 - 366
Sodium Acetate Coated Tenofovir-Loaded Chitosan Nanoparticles for Improved Physico-Chemical Properties Albert N. NgoMiezan J. M. EzoulinBi-Botti C. Youan Research Paper 09 November 2015 Pages: 367 - 383
Aerosolized Non-viral Nucleic Acid Delivery in the Vaginal Tract of Pigs Katrien RemautEvelien De ClercqDaisy Vanrompay Research Paper 30 October 2015 Pages: 384 - 394
Modulation of Cell-Mediated Immunity to Suppress High Fat Diet-Induced Obesity and Insulin Resistance Linna YanKexiu SongDexi Liu Research Paper 28 September 2015 Pages: 395 - 403
Liposome Formation Using a Coaxial Turbulent Jet in Co-Flow Antonio P. CostaXiaoming XuDiane J. Burgess Research Paper 01 October 2015 Pages: 404 - 416
Folate-Conjugated pH-Responsive Nanocarrier Designed for Active Tumor Targeting and Controlled Release of Gemcitabine Ali PourjavadiZahra Mazaheri TehraniAzardokht Abedin Moghanaki Research Paper 05 October 2015 Pages: 417 - 432
Predicting Mouse Liver Microsomal Stability with “Pruned” Machine Learning Models and Public Data Alexander L. PerrymanThomas P. StrattonJoel S. Freundlich Research Paper 28 September 2015 Pages: 433 - 449
Factors Governing the Precision of Subvisible Particle Measurement Methods – A Case Study with a Low-Concentration Therapeutic Protein Product in a Prefilled Syringe Anacelia Ríos QuirozJens LamerzAtanas V. Koulov Research Paper 16 October 2015 Pages: 450 - 461
2D 1HN, 15N Correlated NMR Methods at Natural Abundance for Obtaining Structural Maps and Statistical Comparability of Monoclonal Antibodies Luke W. ArbogastRobert G. BrinsonJohn P. Marino Research Paper 09 October 2015 Pages: 462 - 475
Preclinical Pharmacokinetics Evaluation of Anti-heparin-binding EGF-like Growth Factor (HB-EGF) Monoclonal Antibody Using Cynomolgus Monkeys via 89Zr-immuno-PET Study and the Determination of Drug Concentrations in Serum and Cerebrospinal Fluid Noriyuki KasaiMaiko AdachiKazuya Yamano Research Paper 13 October 2015 Pages: 476 - 486
Drug Permeation Characterization of Inhaled Dry Powder Formulations in Air-Liquid Interfaced Cell Layer Using an Improved, Simple Apparatus for Dispersion Ayumu AsaiTomoyuki OkudaHirokazu Okamoto Research Paper 21 October 2015 Pages: 487 - 497
Model-Based Optimisation of Deferoxamine Chelation Therapy Francesco BellantiGiovanni C. Del VecchioOscar Della Pasqua Research Paper Open access 10 November 2015 Pages: 498 - 509
A Comparison of the Pharmacokinetics and Pulmonary Lymphatic Exposure of a Generation 4 PEGylated Dendrimer Following Intravenous and Aerosol Administration to Rats and Sheep Gemma M. RyanRobert J. BischofLisa M. Kaminskas Research Paper 20 October 2015 Pages: 510 - 525
Comparative Effects of Metal-Catalyzed Oxidizing Systems on Carbonylation and Integrity of Therapeutic Proteins Dmitry KryndushkinV. Ashutosh Rao Research Paper 23 October 2015 Pages: 526 - 539