Abstract
Objectives
Inadequate vitamin D status (25-hydroxyvitamin D (25(OH)D) concentrations <50 nmol/L) is an increasingly important public health issue in Australia. The aim of this analysis is to describe 25(OH)D levels in community dwelling men aged ≥70 years in Sydney, Australia, and to determine associations between serum 25(OH)D levels and socioeconomic and lifestyle factors.
Design
A population-based, crosssectional analysis of the baseline phase of the Concord Health and Ageing in Men Project (CHAMP), a large epidemiological study conducted in Sydney between January 2005 and May 2007.
Participants
1659 noninstitutionalised men aged ≥70 years.
Methods
The cross-sectional analysis of the baseline phase of the Concord Health and Ageing in Men Project (CHAMP), a large epidemiological study conducted in Sydney between January 2005 and May 2007. Participants included 1659 community dwelling men who were interviewed and had clinical assessments. Main outcome measurements included serum 25(OH)D levels measured in blood samples using a radioimmunoassay kit (DiaSorin Inc., Stillwater, MN). Covariates included age, socioeconomic measures, season of blood sample, physical activity, sun exposure, vitamin D supplement use, cigarette smoking status, alcohol consumption, obesity and measures of health.
Results
Prevalence of vitamin D insufficiency was 43.0%; highest in winter (55.5%) and spring (53.9%), and was associated with season (winter and spring), low physical activity, avoidance of sun exposure, current smoking and obesity, even after adjustment for confounding factors.
Conclusion
Inadequate vitamin D status is highly prevalent among Australian older men and is associated with specific lifestyle factors. These findings emphasize the need to screen and monitor 25(OH)D levels in this population group, despite living in a sunny country such as Australia.
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References
Dawson-Hughes B, Heaney RP, Holick MF et al. Estimates of optimal vitamin D status. Osteoporos Int 2005;16:713–16.
Mithal A, Wahl DA, Bonjour JP, Burckhardt P, Dawson-Hughes B, Eisman JA, El-Hajj Fuleihan G, Josse RG, Lips P, Morales-Torres J. Committee IOF., IOF Committee of Scientific Advisors (CSA) Nutrition Working Group Global vitamin D status and determinants of hypovitaminosis D. Osteoporos Int 2009; 20(11): 1807–1820.
Working group of the Australian and New Zealand Bone and Mineral Society, Endocrine Society of Australia and Osteoporosis Australia. Vitamin D and adult bone health in Australia and New Zealand: a position statement. Med J Aust 2012;196(11)18: 686–687.
Holick MF. Vitamin D deficiency. N Engl J Med. 2007; 357: p 266–281.
Holick, M.F., Binkley, N.C., Bischoff-Ferrari, H.A., Gordon, C.M., Hanley, D.A., Heaney, R.P., Murad, M.H. & Weaver, C.M. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 2011; 96: 1911–1930.
Ross, AC, Manson JE, Abrams SA et al. The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know. J Clin Endocrinol Metab. 2011;96: 53–58.
Pearce SH and Cheetham TD. Diagnosis and management of vitamin D deficiency. BMJ 2010; 340:b5664.
Sambrook PN, Cameron ID, Cumming RG et al. Vitamin D deficiency is common in frail institutionalised older people in northern Sydney. Med J Aust 2002; 176:560–560.
Daly RM, Gagnon C, Lu ZX et al. Prevalence of vitamin D deficiency and its determinants in Australian adults aged 25 years and older: A national, populationbased study. Clin Endocrinol (Oxf). 2011. doi: 10.1111/j.1365-2265.2011.04320.x.
Cumming RG, Handelsman D, Seibel MJ, et al. Cohort profile: The Concord Health and Ageing in Men Project (CHAMP). Int J Epidemiol 2009 38:374–378.
NHMRC, Australian Alcohol Guidelines: Health Risks and Benefits. Canberra, NHMRC, N.H.a.M.R. Council, Editor. 2009, Commonwealth of Australia. http://www.nhmrc.gov.au/_files_nhmrc/publications/attachments/ds10-alcohol.pdf (accessed June 2012).
Washburn RA, Smith KW, Jette AM, Janney CA. The Physical Activity Scale for the Elderly (PASE): development and evaluation. J Clin Epidemiol 1993; 46:153–162.
Bruce DG, St John A, Nicklason F, Goldswain PR. Secondary hyperparathyroidism in patients from Western Australia with hip fracture: relationship to type of hip fracture, renal function, and vitamin D deficiency. J Am Geriatr Soc. 1999;47(3):354–9.
Lai JK, Lucas RM, Banks E, Ponsonby AL; Ausimmune Investigator Group. Variability in vitamin D assays impairs clinical assessment of vitamin D status. Intern Med J. 2012; 42(1):43–50.
Maclaughlin J, Holick MF. Aging decreases the capacity of human-skin to produce vitamin-D3. J Clin Invest. 1985; 76(4):1536–8.
Chen TC, Chimeh F, Lu Z et al. Factors that influence the cutaneous synthesis and dietary sources of vitamin D. Arch Biochem Biophys 2007;460:213–217.
Sambrook PN, Cameron ID, Chen JS et al. Does increased sunlight exposure work as a strategy to improve vitamin D status in the elderly: a cluster randomised controlled trial. Osteoporos Int. 2012;23(2):615–624.
Durvasula S, Kok C, Sambrook PN, Cumming RG, Lord SR, March LM, Mason RS, Seibel MJ, Simpson JM, Cameron ID. Sunlight and health: attitudes of older people living in intermediate care facilities in southern Australia. Arch Gerontol Geriatr. 2010;51(3):e94–99.
Baghurst KI, Record SJ. Re-analysis of the 1995 National Nutrition Survey. Adelaide: CSIRO, 2002.
Bischoff-Ferrari HA, Giovannucci E, Willett WC, Dietrich T, Dawson-Hughes B. Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health outcomes. Am J Clin Nut 2006; 84(1):18–28.
Australian Government Bureau of Meteorology, Internet Activity, Australia, Sep 2012. http://www.bom.gov.au/climate/ (accessed May 2012).
Webb AR, Pilbeam C, Hanafin N, Holick MF. An evaluation of the relative contributions of exposure to sunlight and of diet to the circulating concentrations of 25-hydroxyvitamin D in an elderly nursing home population in Boston. Am J Clin Nut 2009; 51; 1075–1081.
Hirani V, Primatesta P. Vitamin D concentrations among people aged 65 years and over living in private households and institutions in England: population survey. Age and Ageing 2005; 34: 485–491.
Flicker L, Mead K, MacInnis RJ et al. Serum Vitamin D and Falls in Older Women in Residential Care in Australia. J Am Geriatr Soc 2003; 51:1533–1538.
Brot C, Jorgensen NR, Sørensen OH. The influence of smoking on vitamin D status and calcium metabolism. Eur J Clin Nutr 1999; 53: 920–926.
Scragg, R, Camargo CA. Frequency of leisure-time physical activity and serum 25-hydroxyvitamin D levels in the US population: results from the Third National Health and Nutrition Examination Survey. Am J Epidemiol 2008;168: 577–586.
Snijder MB, van Dam RM, Visser M et al. Adiposity in relation to vitamin D status and parathyroid hormone levels: a population-based study in older men and women. J Clin Endocrinol Metab 2005; 90: 4119–4123.
Hirani V, Mosdøl A, Mishra G. Predictors of 25-hydroxyvitamin D status among adults in two British national surveys. Br J Nutr 2009; 101: 760–764.
Holden CA, McLachlan RI, Pitts M, et al. Men in Australia Telephone Survey (MATeS): a national survey of the reproductive health and concerns of middle-aged and older Australian men. Lancet 2005; 366: 218–224.
Maggio D, Cherubini A, Lauretani F et al. 25(OH)D serum levels decline with age earlier in women than in men and less efficiently prevent compensatory hyperparathyroidism in older adults. J Gerontol A Biol Sci Med Sci 2005; 60A:1414–1419.
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Hirani, V., Cumming, R.G., Blyth, F.M. et al. Vitamin D status among older community dwelling men living in a sunny country and associations with lifestyle factors: The concord health and ageing in men project, Sydney, Australia. J Nutr Health Aging 17, 587–593 (2013). https://doi.org/10.1007/s12603-013-0013-z
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DOI: https://doi.org/10.1007/s12603-013-0013-z