Abstract
Both medical and engineering sciences play a vital role in human health diagnose and treatment. In this scientific world, the technology of alternative bone scaffold is one of the remedial sources for bone loss treatment. This research paper focuses on the design and analysis of porous scaffold made of additive manufacturing process. Various types of biocompatible materials with different characteristics are used for this bone scaffold. In order to have high load bearing capacity, a material composition of biocompatible Polyamide (PA) combined with Hydroxyapatite (HA) is used in this research work. HA has the character of greater cell seeding growth of tissue cells and hence added in the composition. The porous scaffold models with different configuration of cubical pore, spherical pore, shifted cubical pore, shifted spherical pore are designed using Solidworks software with a pore size of 800 microns and the porosity ranging from 40 % to 70 %. All the CAD models are analyzed using ANSYS software. Based on the static structural analysis, the shifted cubical scaffold posses lesser stress concentration, and thus selected for fabrication using Selective Laser Sintering machine. The specimens are fabricated in three different build orientations and the load bearing strength is found out using experimentation. The different material composition of 100 %PA, 95 %PA: 5 %HA, 90 %PA: 10 %HA and 85 %PA: 15 %HA are considered for this study.
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T. Kumaresan is a Research Scholar of Department of Production Engineering, PSG College of Technology, Coimbatore, India. He received the Master’s Degree from Bharathiar University. He is an Associate member of Institution of Engineers (India) and has more than 10 years of teaching experience.
R. Gandhinathan received the Ph.D. degree in Mechanical Engineering, Bharathiar University, India. He is currently working as Professor in the Departmentof Production Engineering, PSG College of Technology, Coimbatore, India. He is a Fellow in the Institution of Engineers (India) (FIE) and Life Member in Indian Society of Technical Education (MISTE). He has successfully guided five scholars for award of Ph.D. degree. He has published more than 44 research articles in international Journals and national journals. He has published 160 papers in International and National conferences. He is also involved in research projects sponsored by DST, AICTE.
M. Ramu received the Ph.D. degree in Mechanical Engineering, Anna University Chennai, India. He is currently working as Associate Professor in the Department of Mechanical Engineering, PSG College of Technology, Coimbatore, India. He is a member of Institution of Engineers (India) and Life Member in Indian Society of Technical Education (MISTE). He has published more than 45 research articles in international Journals and national journals. He has published more than 15 papers in International and National conferences. He is also involved in research projects sponsored by DST, AICTE, BRNS and IGCAR.
M. Ananthasubramanian has obtained his Ph.D. in Applied Microbiology, from University of Madras, India He is currently the Head of Department of Biotechnology, PSG College of Technology, India. He has received several grants from Government of India, and developed a circular micro fluidic device and BioMEMS based cell sorting device. He has initiated to studying the role of surface characteristics of scaffolds in limiting/effecting the growth of bacterial and mammalian cells. His research also extends to the field of analyzing the Phage diversity and its molecular mechanism of drug resistance in nosocomial infection.
K. Banu Pradheepa is doing her Ph.D. at Department of Biotechnology, PSG College of Technology, India. She is currently working on the techniques to minimize Biomaterial Associated infections in orthopedic implants. Her previous works include ‘In silico prediction of microRNA targets in Plant Mitochondria’, ‘In vitro and in vivo biocompatibility testing of the bone scaffold fabricated using Selective Laser Sintering, in collaboration with the Department of Mechanical Engineering, PSG College of Technology and PSG Institute of Medical Sciences & Research.
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Kumaresan, T., Gandhinathan, R., Ramu, M. et al. Design, analysis and fabrication of polyamide/ hydroxyapatite porous structured scaffold using selective laser sintering method for bio-medical applications. J Mech Sci Technol 30, 5305–5312 (2016). https://doi.org/10.1007/s12206-016-1049-x
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DOI: https://doi.org/10.1007/s12206-016-1049-x