Abstract
Therapy-related acute myelogenous leukemia and myelodysplastic syndrome (t-AML/MDS) are increasing in prevalence with aging of the population and improved survival of patients treated with chemotherapy or radiotherapy for other malignancies. Research focused on the pathogenesis of t-AML/MDS will provide insight into the pathogenesis of de novo AML/MDS. Participation in clinical trials should be encouraged for this patient population because results with available treatment options are clearly suboptimal.
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Borthakur, G., Estey, E.E. Therapy-related acute myelogenous leukemia and myelodysplastic syndrome. Curr Oncol Rep 9, 373–377 (2007). https://doi.org/10.1007/s11912-007-0050-z
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DOI: https://doi.org/10.1007/s11912-007-0050-z