Abstract
Objective
To observe the effect of acupoint injection with Neostigmine Methylsulfate at Zusanli (ST 36) on gastrointestinal function of patients after laparoscopic cholecystectomy.
Methods
Totally 120 patients undergone laparoscopic cholecystectomy were randomized into an acupoint injection group, a muscular injection group, and a blank control group at 1:1:1 by random number table, 40 cases in each group. The blank control group was intervened by conventional post-operation treatment, the acupoint injection group was by acupoint injection with Neostigmine Methylsulfate 2 mL at bilateral Zusanli (ST 36) in addition to the treatment given to the blank control group, and the muscular injection group was by muscular injection with Neostigmine Methylsulfate 2 mL in addition to the treatment given to the blank control group. The two injection groups both received injection twice a day, totally for 3 d at most. The restored time of bowel sounds, initial flatulence time, defecation time and clinical efficacy were observed.
Results
After treatment, there were significant differences in comparing the restored time of bowel sounds among the three groups (F=17.30, P<0.05), the acupoint injection group and muscular injection group were significantly different from the blank control group (P<0.05), and there was a significant difference between the acupoint injection group and muscular injection group (P<0.05); there were significant differences in comparing the initial flatulence time among the three groups (F=19.12, P<0.05), and the acupoint injection group was significantly different from the muscular injection group and the blank control group (P<0.05); there were significant differences in comparing the initial defecation time among the three groups (χ 2=21.23, P<0.05), while the difference between the acupoint injection group and muscular injection group was statistically insignificant (P>0.05). The total effective rate was 87.5% in the acupoint injection group, versus 72.5% in the muscular injection group and 60.0% in the blank control group, and there were significant differences among the three groups (P<0.05).
Conclusion
Acupoint injection with Neostigmine Methylsulfate at Zusanli (ST 36) can shorten the restored time of bowel sounds and flatulence time in patients undergone laparoscopic cholecystectomy, and the efficacy is more significant compared to muscular injection with Neostigmine Methylsulfate.
摘要
目的
观察足三里穴位注射新斯的明对腹腔镜胆囊切术后患者胃肠功能的影响。
方法
将120 例腹腔 镜胆囊切除术患者根据随机数字按照1:1:1 比例分为穴位注射组、肌肉注射组及空白对照组, 每组40 例。空白对 照组给予术后常规治疗, 穴位注射组在常规治疗基础上加用双侧足三里穴位注射新斯的明注射液2 mL, 肌肉注 射组在常规治疗基础上加用肌肉注射新斯的明注射液2 mL。两组均每日治疗2 次, 最多治疗3 d。观察三组患者 术后肠鸣音恢复时间、肛门首次排气时间、排便时间及临床疗效。
结果
治疗后, 三组患者术后肠鸣音恢复时间 比较, 差异具有统计学意义(F=17.30, P<0.05), 穴位注射组、肌肉注射组与空白对照组差异均有统计学意义 (P<0.05), 穴位注射组与肌肉注射组差异有统计学意义(P<0.05); 三组患者术后肛门首次排气时间比较, 差异具 有统计学意义(F=19.12, P<0.05), 穴位注射组与肌肉注射组及空白对照组差异具有统计学意义(P<0.05); 三组 患者术后首次排便时间比较, 三组差异具有统计学意义(χ 2=21.23, P<0.05), 穴位注射组与肌肉注射组差异无统 计学意义(P>0.05)。穴位注射组总有效率为87.5%, 肌肉注射组为72.5%, 空白对照组有效率为60.0%, 三组总有 效率差异具有统计学意义(P<0.05)。
结论
足三里穴位注射新斯的明能够缩短腹腔镜胆囊切除术患者术后肠鸣音 恢复时间及肛门排气时间, 其效果优于肌肉注射新斯的明。
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Qiu, Wq., Jiang, Jy. Effect of acupoint injection of Neostigmine on gastrointestinal function after cholecystectomy. J. Acupunct. Tuina. Sci. 13, 368–372 (2015). https://doi.org/10.1007/s11726-015-0884-0
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DOI: https://doi.org/10.1007/s11726-015-0884-0
Keywords
- Acupoint Therapy
- Hydro-acupuncture
- Points, Zusanli (ST 36)
- Neostigmine
- Laparoscopes
- Cholecystectomy; Postoperative Complications