Abstract
3-Phenylbenzo[c]isoxazoles were synthesized by non-catalytic thermolysis of 2-azidobenzophenones in dry xylene with quantitative yields. The trace content of water in solvents reduces the yields of the reaction products. 2-Azidobenzoic acid esters are stable under the indicated conditions.
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Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 6, pp. 1298–1300, June, 2019.
This work was financially supported by the Ministry of Educa tion and Science of the Russian Federation within the framework of the basic part of the state assignment of the State University of Nizhni Novgorod (Project No. 4.5706.2017/BC).
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Odinokov, A.V., Plekhovich, S.D. & Budruev, A.V. Synthesis of 3-phenylbenzo[c]isoxazoles by thermocyclization of 2-azidobenzophenones. Russ Chem Bull 68, 1298–1300 (2019). https://doi.org/10.1007/s11172-019-2557-5
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DOI: https://doi.org/10.1007/s11172-019-2557-5