We studied the effect of officinal forms and nanoparticles of lithium carbonate and lithium citrate on proliferative activity of hepatoma-29 cells. Lithium carbonate nanoparticles suppressed proliferation of hepatoma-29 cells in lower concentrations than officinal form of this salt. The antiproliferative effect of lithium salts i activation of apoptosis and arrest of hepatoma-29 cells in the G2/M phase of the cell cycle.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 160, No. 12, pp. 802-805, December, 2015
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Lykov, A.P., Poveshchenko, O.V., Bondarenko, N.A. et al. Antiproliferative Potential of Officinal Forms and Nanoparticles of Lithium Salts. Bull Exp Biol Med 160, 827–830 (2016). https://doi.org/10.1007/s10517-016-3320-7
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DOI: https://doi.org/10.1007/s10517-016-3320-7