Summary
Osteoarthritis (OA) can be used as a common name for a group of overlapping pathological conditions when the balance between the processes of degradation and synthesis, in individual parts of the cartilage, is disturbed and leads to gradual cartilage destruction. A preventive approach toward OA helps with a timely diagnosis and subsequent treatment of this disease. One of the significant risk factors affecting development of hip joint OA is the mechanism and magnitude of mechanical loading on the joint. The main motivation for this work was to verify the hypothesis involving a pathologic cycle (overloading – change of locomotion – overloading) as contributory to the development of OA and whether it can be stopped, or at least partly decelerated, by a suitable change of movement stereotypes. Providing that there is a natural balance of muscular action, from the beginning of OA, the development of OA can be significantly decelerated. The return to a natural force balance can be achieved using suitable exercise and strengthening of muscular structures. In order to verify the hypothesis, we undertook experimental measurements of gait kinematics and a computational analysis of the hip joint using the Finite Element Method.
Article PDF
Similar content being viewed by others
Avoid common mistakes on your manuscript.
References
Donzelli PS, Spilker RL, Ateshian GA, et al. Contact analysis of biphasic transversely isotropic cartilage layers and correlations with tissue failure. J Biomech, 32: 1037–1047, 1999
Federico S, Rosa GL, Herzog W, et al. Effect of fluid boundary conditions on joint contact mechanics and applications to the modeling of osteoarthritic joints. J Biomech Eng, 126: 220–225, 2004
Hewitt J, Guilak F, Glisson R, et al. Regional material properties of the human hip joint capsule ligaments. J Orthop Res, 19: 359–364, 2001
Kamekura S, Hoshi K, Shimoaka T, et al. Osteoarthritis development in novel experimental mouse models induced by knee joint instability. Osteoarthr Cartil, 13: 632–641, 2005
Lawrence RC, Helmick CG, Arnett FC, et al. Estimates of the prevalence of arthritis and selected musculoskeletal disorders in the United States. Arthritis Rheum, 41: 778–799, 1998
Li LP, Buschmann MD, Shirazi-Adl A. A fibril reinforced nonhomogeneous poroelastic model for articular cartilage: inhomogeneous response in unconfined compression. J Biomech, 33: 1533–1541, 2000
Moskowitz RW, Altman RD, Buckwalter JA, et al. Osteoarthritis diagnosis and medical/surgical management. Hardbound, 4th edn. Lippicott Williams & Wilkins: Philadelphia, 2007
Mow VC, Kuei SC, Lai WM, et al. Biphasic creep and stress relaxation of articular cartilage in compression: theory and experiments. J Biomech Eng, 102: 73–84, 1980
Radin EL, Paul IL, Lowy M. A comparison of the dynamic force transmitting properties of subchondral bone and articular cartilage. J Bone Joint Surg, 52: 444–456, 1970
Stewart KJ, Edmonds-Wilson RH, Brand RA, et al. Spatial distribution of hip capsule structural and material properties. J Biomech, 35: 1491–1498, 2002
Suh JK, Bai S. Finite element formulation of biphasic poroviscoelastic model for articular cartilage. J Biomech Eng, 120: 195–201, 1997
Lewit K. Manipulative Therapy in rehabilitation of the locomotor system, 3rd edn. Butterworth, Oxford, 1999
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Horak, Z., Kubovy, P., Stupka, M. et al. Biomechanical factors influencing the beginning and development of osteoarthritis in the hip joint. Wien Med Wochenschr 161, 486–492 (2011). https://doi.org/10.1007/s10354-011-0906-6
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10354-011-0906-6