Abstract
Good syndrome (GS) is a rare adult-onset immunodeficiency disease characterised by hypogammaglobulinaemia and thymoma. Here we describe a 72-yearold male patient who was diagnosed with GS when he was 62, after a two-year history of recurrent respiratory infections. A chest CT scan showed a mediastinal mass which was surgically removed; its histology revealed a thymoma. The patient was hypogammaglobulinaemic and his clinical condition dramatically improved after starting an appropriate dosage of IVIG. Two years ago he developed a normochromic normocytic anaemia requiring several transfusions. A bone marrow biopsy revealed a myelodysplastic syndrome. The patient started cyclosporine and the anaemia gradually improved, achieving transfusion independence.
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Di Renzo, M., Pasqui, A.L., Voltolini, L. et al. Myelodysplasia and Good syndrome. A case report. Clin Exp Med 8, 171–173 (2008). https://doi.org/10.1007/s10238-008-0175-x
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DOI: https://doi.org/10.1007/s10238-008-0175-x