Abstract
A multiscale approach (periodic homogenization) is carried out to model osteon’s behaviour, and especially the coupled phenomena that govern its interstitial fluid movement. Actions of electro-osmotic and osmotic motions in addition to the classical Poiseuille flow are studied at the mesoscale of the canaliculus and within the micropores of the collagen-apatite matrix. Use of this fully coupled modelling leads to a comparison of these different effects. Limitation of a classical Darcian description of the fluid flow at the two scales is so studied. For each of these studies a special attention is given to the pore’s geometry influence and to their electrical and hydraulic properties
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Lemaire, T., Naïli, S. & Rémond, A. Multiscale analysis of the coupled effects governing the movement of interstitial fluid in cortical bone. Biomech Model Mechanobiol 5, 39–52 (2006). https://doi.org/10.1007/s10237-005-0009-7
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DOI: https://doi.org/10.1007/s10237-005-0009-7