Abstract
. Simultaneous application of multiple fibres could increase the volume of coagulation produced with interstitial laser photocoagulation (ILP) for solid tumours. To take full advantage of the presumed synergistic thermal effect between the fibres, the optimal combination of laser power and distance between the fibres was investigated. Four fibres with a cylindrical diffusing tip of 2 cm length were used, coupled to an optical beamsplitter for Nd:YAG light (four channels, maximal variation 9.5%, transmission >85%). The distance between the fibres was 1, 1.5, 2, 2.5 , 3 or 4 cm with a power output of either 4, 5, 6 or 7 W/fibre; energy per fibre was constant at 1800 J by adjusting exposure time. After laser application, dimensions of the coagulated lesions were measured.
The optimal mutual fibre distance was 2 cm ( p<0.01) at all power levels. This resulted in lesions with a mean (SD) volume of 44.5 (2.1) cm3 and a largest diameter of 5.1 (0.4) cm at 7 W/fibre. Smaller distances between the fibres resulted in smaller lesions with central carbonisation, whereas larger distances resulted in four separate zones of coagulation. It was concluded that simultaneous application of four interstitial fibres may result in a considerable increase of volume of coagulation. Fibre position and mutual fibre distance determines whether synergism of the coagulative effect occurs.
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Paper received 14 July 1998; accepted following revision 18 January 1999
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Heisterkamp, J., Van Hillegersberg, R., Sinofsky, E. et al. Interstitial Laser Photocoagulation with Four Cylindrical Diffusing Fibre Tips: Importance of Mutual Fibre Distance. Lasers Med Sci 14, 216–220 (1999). https://doi.org/10.1007/s101030050087
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DOI: https://doi.org/10.1007/s101030050087