Summary
A 22-year-old man presented with a rare case of atypical teratoid/rhabdoid tumour (AT/RT). Magnetic resonance imaging showed a left cerebellar mass with leptomeningeal dissemination. Partial resection was performed. Histological examination revealed AT/RT. Postoperatively, whole neuraxis and local irradiation were performed. Three-drug chemotherapy with ifosfamide, cisplatin, and etoposide, and adjuvant intrathecal administration of methotrexate were repeated. Near complete response was achieved, and no tumour recurrence/progression has been noticed during the follow up of 24 months. Intensive radiochemotherapy can successfully control AT/RT, even with leptomeningeal dissemination.
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Kawaguchi, T., Kumabe, T., Watanabe, M. et al. Atypical teratoid/rhabdoid tumour with leptomeningeal dissemination in an adult. Acta Neurochir 146, 1033–1038 (2004). https://doi.org/10.1007/s00701-004-0313-5
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DOI: https://doi.org/10.1007/s00701-004-0313-5